ArticleCancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology2017
Quantifying the Genetic Correlation between Multiple Cancer Types.
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Article in Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 3 of them syntheses that pooled it.
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31citing papers in PubMed, 3 pooled it
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What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
31 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Pan-cancer and cross-population genome-wide association studies dissect shared genetic backgrounds underlying carcinogenesis.Nature communications · 2023Pooled it
- The Shared Genetic Architectures Between Lung Cancer and Multiple Polygenic Phenotypes in Genome-Wide Association Studies.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2021Pooled it
- Cross-cancer evaluation of polygenic risk scores for 16 cancer types in two large cohorts.Nature communications · 2021Pooled it
- Genomic structural equation modelling of 12 cancers identifies a latent pan-cancer susceptibility factor and shared determinants of carcinogenesis.EBioMedicine · 2026Article
- The Importance of Regulatory Network Structure for Complex Trait Heritability and Evolution.Molecular biology and evolution · 2025Article
- Investigating the Relationships Between Neurodegenerative Diseases and Cancer Types: A Computational Approach.Current Alzheimer research · 2025Article
- A scalable approach to characterize pleiotropy across thousands of human diseases and complex traits using GWAS summary statistics.American journal of human genetics · 2023Article
- Spatial Difference Boundary Detection for Multiple Outcomes Using Bayesian Disease Mapping.Biostatistics (Oxford, England) · 2023Article
- Genome-wide analyses characterize shared heritability among cancers and identify novel cancer susceptibility regions.Journal of the National Cancer Institute · 2023Article
- A scalable variational approach to characterize pleiotropic components across thousands of human diseases and complex traits using GWAS summary statistics.medRxiv : the preprint server for health sciences · 2023Article
- Canonical and Noncanonical ER Stress-Mediated Autophagy Is a Bite the Bullet in View of Cancer Therapy.Cells · 2022Review
- Assessment of genetic susceptibility to multiple primary cancers through whole-exome sequencing in two large multi-ancestry studies.BMC medicine · 2022Article
- Hierarchical multivariate directed acyclic graph autoregressive models for spatial diseases mapping.Statistics in medicine · 2022Article
- Considering hormone-sensitive cancers as a single disease in the UK biobank reveals shared aetiology.Communications biology · 2022Article
- Immunogenetic clustering of 30 cancers.Scientific reports · 2022Article
- Associations of genetic susceptibility to 16 cancers with risk of breast cancer overall and by intrinsic subtypes.HGG advances · 2022Article
- Large-scale cross-cancer fine-mapping of the 5p15.33 region reveals multiple independent signals.HGG advances · 2021Article
- Genetic correlation and causal relationships between cardio-metabolic traits and lung function impairment.Genome medicine · 2021Article
- A powerful method for pleiotropic analysis under composite null hypothesis identifies novel shared loci between Type 2 Diabetes and Prostate Cancer.PLoS genetics · 2020Article
- Association between inflammatory bowel disease and prostate cancer: A large-scale, prospective, population-based study.International journal of cancer · 2020Article
Corrections and comments
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Authors and funding
32 authors.
Sara LindströmDepartment of Epidemiology, University of Washington, Seattle, Washington. saralind@uw.edu.
Hilary FinucaneProgram in Genetic Epidemiology and Statistical Genetics, Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, Massachusetts.
Brendan Bulik-SullivanThe Analytic and Translational Genetics Unit, Massachusetts General Hospital, Boston, Massachusetts.
Fredrick R SchumacherDepartment of Epidemiology and Biostatistics, Case Western Reserve University, Cleveland, Ohio.
Christopher I AmosDepartment of Community and Family Medicine, Geisel School of Medicine at Dartmouth, Hanover, New Hampshire.
Rayjean J HungLunenfeld-Tanenbaum Research Institute, Sinai Health System, Toronto, Ontario, Canada.
Kristin RandDepartment of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California.
Stephen B GruberDepartment of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California.
David ContiDepartment of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California.
Jennifer B PermuthDepartment of Cancer Epidemiology, Moffitt Cancer Center and Research Institute, Tampa, Florida.
Hui-Yi LinDepartment of Biostatistics and Bioinformatics, Moffitt Cancer Center, Tampa, Florida.
Ellen L GoodeDepartment of Health Sciences Research, Mayo Clinic College of Medicine, Rochester, Minnesota.
Thomas A SellersDepartment of Cancer Epidemiology, Moffitt Cancer Center and Research Institute, Tampa, Florida.
Laufey T AmundadottirDivision of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, U.S. Department of Health and Human Services, Bethesda, Maryland.
Rachael Stolzenberg-SolomonDivision of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, U.S. Department of Health and Human Services, Bethesda, Maryland.
Alison KleinDepartment of Oncology, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins School of Medicine, Baltimore, Maryland.
Gloria PetersenDepartment of Health Sciences Research, Mayo Clinic College of Medicine, Rochester, Minnesota.
Harvey RischDepartment of Chronic Disease Epidemiology, Yale School of Public Health, New Haven, Connecticut.
Brian WolpinDepartment of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts.
Li HsuDivision of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington.
Jeroen R HuygheDivision of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington.
Jenny Chang-ClaudeDivision of Cancer Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Germany.
Andrew ChanDivision of Gastroenterology, Massachusetts General Hospital, Boston, Massachusetts.
Sonja BerndtDivision of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, U.S. Department of Health and Human Services, Bethesda, Maryland.
Rosalind EelesDivision of Genetics and Epidemiology, The Institute of Cancer Research, and Royal Marsden NHS Foundation Trust, London, United Kingdom.
Douglas EastonCentre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge, United Kingdom.
Christopher A HaimanDepartment of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California.
David J HunterProgram in Genetic Epidemiology and Statistical Genetics, Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, Massachusetts.
Benjamin NealeThe Analytic and Translational Genetics Unit, Massachusetts General Hospital, Boston, Massachusetts.
Alkes L PriceProgram in Genetic Epidemiology and Statistical Genetics, Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, Massachusetts.
Peter KraftProgram in Genetic Epidemiology and Statistical Genetics, Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, Massachusetts.
PanScan, GECCO and the GAME-ON Network: CORECT, DRIVE, ELLIPSE, FOCI, and TRICL-ILCCO
Funding
TRANSLATIONAL RESEARCHP30CA076292 · NCI · UNIVERSITY OF SOUTH FLORIDA · PI Christine O'Connell · 1998 to 2026
$93.5MTranslational Engineering in Cancer (TEC)P30CA023108 · NCI · DARTMOUTH COLLEGE · PI Fred W Kolling IV · 1985 to 2026
$91.3MStatistical MethodsP01CA087969 · NCI · BRIGHAM AND WOMEN'S HOSPITAL · PI ROSNER, BERNARD A · 2000 to 2019
$77.8MTumor Antigens for Individual Signatures and TherapyP50CA062924 · NCI · JOHNS HOPKINS UNIVERSITY · PI JAFFEE, ELIZABETH M. · 1993 to 2022
$54.6MValidity of Diet and Activity Measures in WomenP01CA055075 · NCI · HARVARD UNIVERSITY (SCH OF PUBLIC HLTH) · PI RIMM, ERIC B · 1991 to 2009
$41.8MTissue and Pathology ResourcesP50CA127003 · NCI · DANA-FARBER CANCER INST · PI BASS, ADAM JOEL · 2007 to 2023
$33.2MRisk Factors for Breast Cancer in Younger NursesR01CA050385 · NCI · HARVARD UNIVERSITY (SCH OF PUBLIC HLTH) · PI ELIASSEN, A. HEATHER, WILLETT, WALTER C. · 1989 to 2019
$32.3MPLCO Trial Etiologic and Early Marker StudyZIACP010152 · NCI · DIVISION OF CANCER EPIDEMIOLOGY AND GENETICS · PI MOORE, STEVEN · 2009 to 2025
$29.9MJH/CIDR Genotyping for Genome-Wide Association StudiesU01HG004438 · NHGRI · JOHNS HOPKINS UNIVERSITY · PI VALLE, DAVID · 2007 to 2011
$24.2MGENETIC SUSCEPTIBILITY TO CANCER IN MULTIETHNIC COHORTSR01CA063464 · NCI · UNIVERSITY OF SOUTHERN CALIFORNIA · PI HENDERSON, BRIAN E · 2001 to 2005
$23.2MMultiethnic Cohort Study of Diet and CancerR37CA054281 · NCI · UNIVERSITY OF HAWAII AT MANOA · PI KOLONEL, LAURENCE N. · 2003 to 2012
$23.2MLong Term Multidisciplinary Study of Cancer in Women: The Nurses Health StudyUM1CA186107 · NCI · BRIGHAM AND WOMEN'S HOSPITAL · PI ELIASSEN, A. HEATHER, STAMPFER, MEIR · 2014 to 2023
$22.3MCancer Research UK A12014Intramural NIH HHS Z01 CP010200NCI NIH HHS K05 CA154337NCI NIH HHS K07 CA190673NCI NIH HHS P01 CA033619NCI NIH HHS P01 CA055075NCI NIH HHS P01 CA087969NCI NIH HHS P30 CA023108NCI NIH HHS P30 CA076292NCI NIH HHS P50 CA062924NCI NIH HHS P50 CA127003NCI NIH HHS R01 CA042182NCI NIH HHS R01 CA048998NCI NIH HHS R01 CA049449NCI NIH HHS R01 CA050385NCI NIH HHS R01 CA054281NCI NIH HHS R01 CA060987NCI NIH HHS R01 CA063464NCI NIH HHS R01 CA067262NCI NIH HHS R01 CA076366NCI NIH HHS R01 CA137178NCI NIH HHS R01 CA143237NCI NIH HHS R01 CA151993NCI NIH HHS R01 CA154823NCI NIH HHS R01 CA189532NCI NIH HHS R01 CA194393NCI NIH HHS R01 CA195789NCI NIH HHS R03 CA173785NCI NIH HHS R35 CA197449NCI NIH HHS R35 CA197735NCI NIH HHS R37 CA054281NCI NIH HHS U01 CA074783NCI NIH HHS U01 CA074794NCI NIH HHS U01 CA122839NCI NIH HHS U01 CA137088NCI NIH HHS U01 CA164930NCI NIH HHS U01 CA167552NCI NIH HHS U01 CA194393NCI NIH HHS U19 CA148065NCI NIH HHS U19 CA148107NCI NIH HHS U19 CA148112NCI NIH HHS U19 CA148127NCI NIH HHS U19 CA148537NCI NIH HHS U24 CA074783NCI NIH HHS U24 CA074794NCI NIH HHS UM1 CA167551NCI NIH HHS UM1 CA167552NCI NIH HHS UM1 CA176726NCI NIH HHS UM1 CA186107NHGRI NIH HHS U01 HG004438NHGRI NIH HHS U01 HG004446NHLBI NIH HHS HHSN268201100001INHLBI NIH HHS HHSN268201100002INHLBI NIH HHS HHSN268201100003INHLBI NIH HHS HHSN268201100004INHLBI NIH HHS HHSN268201100046CNHLBI NIH HHS HHSN268201200008CNHLBI NIH HHS HHSN268201200008INIA NIH HHS HHSN271201100004CWHI NIH HHS HHSN268201100001CWHI NIH HHS HHSN268201100002CWHI NIH HHS HHSN268201100003CWHI NIH HHS HHSN268201100004C
Abstract
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FemaleGenetic Predisposition to DiseaseGenetic VariationGenome-Wide Association StudyHumansMaleNeoplasmsRisk Factors
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