Evidence map›Paper›PMID 28637791›Full record

ArticleAmerican journal of physiology. Renal physiology2017

Store-operated calcium entry suppressed the TGF-β1/Smad3 signaling pathway in glomerular mesangial cells.

Sarika Chaudhari, Weizu Li, Yanxia Wang, Hui Jiang, Yuhong Ma, Mark E Davis, Jonathan E Zuckerman, Rong Ma

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in American journal of physiology. Renal physiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
0.9field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 22 citations in OpenAlex.

  1. Article
  2. I-mfa, Mesangial Cell TRPC1 Channel, and Regulation of GFR.Journal of the American Society of Nephrology : JASN · 2025
    Article
  3. Review
  4. Article
  5. Non-voltage-gated CaAmerican journal of physiology. Renal physiology · 2024
    Review
  6. Store-operated CaExperimental biology and medicine (Maywood, N.J.) · 2023
    Review
  7. Review
  8. Review
  9. Enhanced Orai1-mediated store-operated CaThe Journal of biological chemistry · 2022
    Article
  10. Review
  11. Store-operated calcium entry: Pivotal roles in renal physiology and pathophysiology.Experimental biology and medicine (Maywood, N.J.) · 2021
    Review
  12. Article
  13. Article
  14. Calcium Sets the Clock in Ameloblasts.Frontiers in physiology · 2020
    Article
  15. Article
  16. Article
  17. Store-Operated CaContact (Thousand Oaks (Ventura County, Calif.))
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 2 countries.

Sarika ChaudhariInstitute for Cardiovascular and Metabolic Diseases, University of North Texas Health Science Center, Fort Worth, Texas.
Weizu LiInstitute for Cardiovascular and Metabolic Diseases, University of North Texas Health Science Center, Fort Worth, Texas.
Yanxia WangInstitute for Cardiovascular and Metabolic Diseases, University of North Texas Health Science Center, Fort Worth, Texas.
Hui JiangInstitute for Cardiovascular and Metabolic Diseases, University of North Texas Health Science Center, Fort Worth, Texas.
Yuhong MaInstitute for Cardiovascular and Metabolic Diseases, University of North Texas Health Science Center, Fort Worth, Texas.
Mark E DavisDepartment of Chemical Engineering, California Institute of Technology, Pasadena, California.
Jonathan E ZuckermanDepartment of Chemical Engineering, California Institute of Technology, Pasadena, California.
Rong MaInstitute for Cardiovascular and Metabolic Diseases, University of North Texas Health Science Center, Fort Worth, Texas; rong.ma@unthsc.edu.
University of North Texas Health Science Center · USCalifornia Institute of Technology · USUniversity of North Texas · USAnhui Medical University · CN

Funding

NADPH oxidases-derived ROS downregulate TRPC6 in mesangial cells in diabetesR01DK079968 · NIDDK · UNIVERSITY OF NORTH TEXAS HLTH SCI CTR · PI MA, RONG · 2009 to 2013
$1.5M
Store-operated Ca2+ signaling in kidney glomerular mesangial cellsR01DK115424 · NIDDK · UNIVERSITY OF NORTH TEXAS HLTH SCI CTR · PI MA, RONG · 2018 to 2021
$1.3M
NIDDK NIH HHS R01 DK079968NIDDK NIH HHS R01 DK115424
6 · The paper itself

Abstract

Our previous study demonstrated that the abundance of extracellular matrix proteins was suppressed by store-operated Ca

Indexed as

Calcium SignalingActive Transport, Cell NucleusAnimalsCalcium Channel BlockersCells, CulturedCollagen Type IVEnzyme InhibitorsFibronectinsHumansMaleMesangial CellsMice, Inbred C57BLORAI1 ProteinPhosphorylationRNA InterferenceSarcoplasmic Reticulum Calcium-Transporting ATPasesCalcium Channel BlockersCollagen Type IVEnzyme InhibitorsFibronectinsORAI1 ProteinORAI1 protein, humanOrai1 protein, mouseSarcoplasmic Reticulum Calcium-Transporting ATPasesSmad3 ProteinSMAD3 protein, humanSmad3 protein, mouseTGFB1 protein, humanTransforming Growth Factor beta1mesangial cellsOrai1Smad3store-operated Ca2+ entrytransforming growth factor-β1

Identifiers

PMID28637791
PMCPMC5625109
OpenAlexW2644171986

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.