Evidence map›Paper›PMID 28637786›Full record

ArticleAmerican journal of physiology. Renal physiology2017

The role of capsaicin-sensitive C-fiber afferent pathways in the control of micturition in spinal-intact and spinal cord-injured mice.

Katsumi Kadekawa, Tsuyoshi Majima, Takahiro Shimizu, Naoki Wada, William C de Groat, Anthony J Kanai, Momokazu Goto, Mitsuharu Yoshiyama, Kimio Sugaya, Naoki Yoshimura

Open access · bronzeAbstract read
In one paragraph

Article in American journal of physiology. Renal physiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed, 1 pooled it
3.8field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 1 synthesis or guideline pooled it, 40 citations in OpenAlex.

  1. Pooled it
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  11. Nerve growth factor-mediated NaLife sciences · 2022
    Article
  12. Spinal interneurons of the lower urinary tract circuits.Autonomic neuroscience : basic & clinical · 2021
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 2 countries.

Katsumi KadekawaDepartment of Urology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania.
Tsuyoshi MajimaDepartment of Urology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania.
Takahiro ShimizuDepartment of Urology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania.
Naoki WadaDepartment of Urology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania.
William C de GroatDepartment of Pharmacology and Cell Biology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania.
Anthony J KanaiDepartment of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania.
Momokazu GotoDepartment of Urology, Nagoya University Graduate School of Medicine, Nagoya, Japan; and.
Mitsuharu YoshiyamaDepartment of Pharmacology and Cell Biology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania.
Kimio SugayaSouthern Knights' Laboratory, Okinawa, Japan.
Naoki YoshimuraDepartment of Urology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania; nyos@pitt.edu.
University of Pittsburgh · USNagoya University · JPUniversity of Yamanashi · JP

Funding

Urothelium in Detrusor OveractivityP01DK093424 · NIDDK · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI DEGROAT, WILLIAM C · 2013 to 2017
$7.9M
PDE5 Inhibition of Afferents and Interstitial Cells in Overactive Mouse BladdersR01DK098361 · NIDDK · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI BIRDER, LORI A, KANAI, ANTHONY JOHN · 2014 to 2024
$5.7M
NIDDK NIH HHS P01 DK093424NIDDK NIH HHS R01 DK098361
6 · The paper itself

Abstract

We examined bladder and urethral sphincter activity in mice with or without spinal cord injury (SCI) after C-fiber afferent desensitization induced by capsaicin pretreatment and changes in electrophysiological properties of mouse bladder afferent neurons 4 wk after SCI. Female C57BL/6N mice were divided into four groups:

Indexed as

Action PotentialsAnimalsCapsaicinDisease Models, AnimalElectromyographyFemaleGanglionic BlockersMice, Inbred C57BLNerve Fibers, UnmyelinatedNeurons, AfferentPatch-Clamp TechniquesPressureSensory System AgentsSpinal Cord InjuriesTime FactorsUrethraCapsaicinGanglionic BlockersSensory System AgentsC-fiber, capsaicinmicemicturitionspinal cord injury

Identifiers

PMID28637786
PMCPMC5625111
OpenAlexW2708466117

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.