Evidence map›Paper›PMID 28637749›Full record

ArticleThe Journal of cell biology2017

Cell cycle-dependent spatial segregation of telomerase from sites of DNA damage.

Faissal Ouenzar, Maxime Lalonde, Hadrien Laprade, Geneviève Morin, Franck Gallardo, Samuel Tremblay-Belzile, Pascal Chartrand

Open access · bronzeAbstract read
In one paragraph

Article in The Journal of cell biology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
0.9field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 18 citations in OpenAlex.

  1. Article
  2. Article
  3. A comprehensive map of hotspots of de novo telomere addition inbioRxiv : the preprint server for biology · 2023
    Article
  4. Role and Regulation of Pif1 Family Helicases at the Replication Fork.International journal of molecular sciences · 2022
    Review
  5. Article
  6. Review
  7. Review
  8. Article
  9. Review
  10. Article
  11. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Faissal OuenzarDepartment of Biochemistry and Molecular Medicine, Université de Montréal, Montréal, Quebec, Canada.ORCID 0000-0002-9148-5650
Maxime LalondeDepartment of Biochemistry and Molecular Medicine, Université de Montréal, Montréal, Quebec, Canada.
Hadrien LapradeDepartment of Biochemistry and Molecular Medicine, Université de Montréal, Montréal, Quebec, Canada.
Geneviève MorinDepartment of Biochemistry and Molecular Medicine, Université de Montréal, Montréal, Quebec, Canada.
Franck GallardoDepartment of Biochemistry and Molecular Medicine, Université de Montréal, Montréal, Quebec, Canada.
Samuel Tremblay-BelzileDepartment of Biochemistry and Molecular Medicine, Université de Montréal, Montréal, Quebec, Canada.
Pascal ChartrandDepartment of Biochemistry and Molecular Medicine, Université de Montréal, Montréal, Quebec, Canada p.chartrand@umontreal.ca.ORCID 0000-0002-3006-7279
Université de Montréal · CA

Funding

CIHR MOP-89768
6 · The paper itself

Abstract

Telomerase can generate a novel telomere at DNA double-strand breaks (DSBs), an event called de novo telomere addition. How this activity is suppressed remains unclear. Combining single-molecule imaging and deep sequencing, we show that the budding yeast telomerase RNA (

Indexed as

Cell CycleDNA Breaks, Double-StrandedDNA RepairActive Transport, Cell NucleusBleomycinCell NucleolusDNA, FungalDNA HelicasesHigh-Throughput Nucleotide SequencingRad52 DNA Repair and Recombination ProteinRNARNA, FungalSaccharomyces cerevisiaeSaccharomyces cerevisiae ProteinsSingle Molecule ImagingSumoylationBleomycinCdc13 protein, S cerevisiaeDNA, FungalDNA HelicasesPIF1 protein, S cerevisiaeRad52 DNA Repair and Recombination ProteinRAD52 protein, S cerevisiaeRNARNA, FungalSaccharomyces cerevisiae ProteinsSiz1 protein, S cerevisiaeTelomerasetelomerase RNATelomere-Binding ProteinsUbiquitin-Protein Ligases

Identifiers

PMID28637749
PMCPMC5551704
OpenAlexW2649583764

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.