Trial reportPhysiological reports2017
Hypohydration impairs endurance performance: a blinded study.
Trial report in Physiological reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04742530 (Effects of Extended Fasting Prior to Evening Exercise on Appetite, Energy Intake and Performance.), which is not on this map. Cited by 30 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Effects of Extended Fasting Prior to Evening Exercise on Appetite, Energy Intake and Performance.
Who cites it
30 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- The Effect of Heat Stress and Dehydration on Carbohydrate Use During Endurance Exercise: A Systematic Review and Meta-Analysis.Sports medicine (Auckland, N.Z.) · 2025Pooled it
- The Hydrating Effects of Hypertonic, Isotonic and Hypotonic Sports Drinks and Waters on Central Hydration During Continuous Exercise: A Systematic Meta-Analysis and Perspective.Sports medicine (Auckland, N.Z.) · 2022Pooled it
- Efficacy of Heat Mitigation Strategies on Core Temperature and Endurance Exercise: A Meta-Analysis.Frontiers in physiology · 2019Pooled it
- Trial
- Bolus Ingestion of Whey Protein Immediately Post-Exercise Does Not Influence Rehydration Compared to Energy-Matched Carbohydrate Ingestion.Nutrients · 2018Trial
- Hypohydration impairs endurance performance: a blinded study.Physiological reports · 2017Trial
- Inadequate fluid replacement during prolonged cycling in the heat impairs time trial performance independent of serum sodium concentrations.European journal of applied physiology · 2026Article
- At least 10 minutes of seated rest is required for stabilisation of blood-based hydration biomarkers.European journal of applied physiology · 2026Article
- Recommendations for Optimizing Research Regarding the Effects of Dehydration on Athletic Performance.Sports medicine (Auckland, N.Z.) · 2026Review
- Perspectives on enhancing human performance in the heat: Is the solution to simply "just add water"?Sports medicine and health science · 2025Review
- Nourishing Physical Productivity and Performance On a Warming Planet - Challenges and Nutritional Strategies to Mitigate Exertional Heat Stress.Current nutrition reports · 2024Review
- Hypohydration induced by prolonged cycling in the heat increases biomarkers of renal injury in males.European journal of applied physiology · 2024Article
- Article
- Fluid Balance, Sodium Losses and Hydration Practices of Elite Squash Players during Training.Nutrients · 2023Article
- Effects of Different Hydration Strategies in Young Men during Prolonged Exercise at Elevated Ambient Temperatures on Pro-Oxidative and Antioxidant Status Markers, Muscle Damage, and Inflammatory Status.Antioxidants (Basel, Switzerland) · 2023Article
- Assessment of Changes in Physiological Markers in Different Body Fluids at Rest and after Exercise.Nutrients · 2022Review
- Corticospinal and peripheral responses to heat-induced hypo-hydration: potential physiological mechanisms and implications for neuromuscular function.European journal of applied physiology · 2022Review
- Impact of dehydration on perceived exertion during endurance exercise: A systematic review with meta-analysis.Journal of exercise science and fitness · 2022Review
- Awareness of Fluid Losses Does Not Impact Thirst during Exercise in the Heat: A Double-Blind, Cross-Over Study.Nutrients · 2021Article
- Nutritional approaches to counter performance constraints in high-level sports competition.Experimental physiology · 2021Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The general scientific consensus is that starting exercise with hypohydration >2% body mass impairs endurance performance/capacity, but most previous studies might be confounded by a lack of subject blinding. This study examined the effect of hypohydration in a single blind manner using combined oral and intragastric rehydration to manipulate hydration status. After familiarization, seven active males (mean ± SD: age 25 ± 2 years, height 1.79 ± 0.07, body mass 78.6 ± 6.2,
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.