Evidence map›Paper›PMID 28637693›Full record

ArticleGenes & development2017

Neuroblast differentiation during development and in neuroblastoma requires KIF1Bβ-mediated transport of TRKA.

Stuart M Fell, Shuijie Li, Karin Wallis, Anna Kock, Olga Surova, Vilma Rraklli, Carolin S Höfig, Wenyu Li, Jens Mittag, Marie Arsenian Henriksson and 4 more

Open access · diamondAbstract read
In one paragraph

Article in Genes & development, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 26 citations in OpenAlex.

  1. Article
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  3. Update on the genetics of paragangliomas.Endocrine-related cancer · 2023
    Review
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  7. Review
  8. Ocular surface involvement in patients with neurofibromatosis type 1 syndrome.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2020
    Observational
  9. Article
  10. Article
  11. Article
  12. EglN3 hydroxylase stabilizes BIM-EL linking VHL type 2C mutations to pheochromocytoma pathogenesis and chemotherapy resistance.Proceedings of the National Academy of Sciences of the United States of America · 2019
    Article
  13. Article
  14. Combined epigenetic and differentiation-based treatment inhibits neuroblastoma tumor growth and links HIF2α to tumor suppression.Proceedings of the National Academy of Sciences of the United States of America · 2017
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 5 institutions in 3 countries.

Stuart M FellLudwig Institute for Cancer Research Ltd., SE-17177 Stockholm, Sweden.
Shuijie LiLudwig Institute for Cancer Research Ltd., SE-17177 Stockholm, Sweden.
Karin WallisLudwig Institute for Cancer Research Ltd., SE-17177 Stockholm, Sweden.
Anna KockDepartment of Women's and Children's Health, Karolinska Institutet, SE-17176 Stockholm, Sweden.
Olga SurovaLudwig Institute for Cancer Research Ltd., SE-17177 Stockholm, Sweden.
Vilma RraklliLudwig Institute for Cancer Research Ltd., SE-17177 Stockholm, Sweden.
Carolin S HöfigInstitute of Experimental Endocrinology, Charité-Universitätsmedizin Berlin, 13353 Berlin, Germany.
Wenyu LiDepartment of Microbiology and Tumor and Cell Biology, Karolinska Institutet, SE-17177 Stockholm, Sweden.
Jens MittagCenter of Brain, Behavior, and Metabolism, University of Lübeck, 23538 Lübeck, Germany.
Marie Arsenian HenrikssonDepartment of Microbiology and Tumor and Cell Biology, Karolinska Institutet, SE-17177 Stockholm, Sweden.
Rajappa S KenchappaMoffitt Cancer Center, Neuro-Oncology Program, Tampa, Florida 33612, USA.
Johan HolmbergLudwig Institute for Cancer Research Ltd., SE-17177 Stockholm, Sweden.
Per KognerDepartment of Women's and Children's Health, Karolinska Institutet, SE-17176 Stockholm, Sweden.
Susanne SchlisioLudwig Institute for Cancer Research Ltd., SE-17177 Stockholm, Sweden.ORCID 0000-0002-2605-3771
Karolinska Institutet · SELudwig Cancer Research · SEBerlin Institute of Health at Charité - Universitätsmedizin Berlin · DEUniversity of Lübeck · DEWinnMed · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We recently identified pathogenic

Indexed as

AnimalsApoptosisCell DifferentiationCell Line, TumorGene Expression Regulation, DevelopmentalGene SilencingKinesinsMutationNeuroblastomaNeurodegenerative DiseasesNeurofibromin 1NeuronsPC12 Cellsras ProteinsRatsReceptor, trkAKif1b protein, mouseKinesinsNeurofibromin 1ras ProteinsReceptor, trkAchromosome 1p36 lossKIF1Bβneuroblast differentiationneuroblastomaNGFTRKA

Identifiers

PMID28637693
PMCPMC5495120
OpenAlexW2643128081

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.