Evidence map›Paper›PMID 28636816›Full record

ArticleEnvironmental science & technology2017

Impacts of the Mitochondrial Genome on the Relationship of Long-Term Ambient Fine Particle Exposure with Blood DNA Methylation Age.

Jamaji C Nwanaji-Enwerem, Elena Colicino, Lingzhen Dai, Akin Cayir, Marco Sanchez-Guerra, Hannah E Laue, Vy T Nguyen, Qian Di, Allan C Just, Lifang Hou and 5 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Environmental science & technology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Characteristics of cohort studies of long-term exposure to PMEnvironmental science and pollution research international · 2019
    Pooled it
  3. Breathing carcinogens: PMJournal of thoracic disease · 2026
    Review
  4. Article
  5. Review
  6. Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Relationships of Long-Term Smoking and Moist Snuff Consumption With a DNA Methylation Age Relevant Smoking Index: An Analysis in Buccal Cells.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2019
    Article
  15. Review
  16. Review
  17. Review
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Jamaji C Nwanaji-EnweremDepartment of Environmental Health, Harvard T.H. Chan School of Public Health , Boston, Massachusetts, 02115, United States.
Elena ColicinoDepartment of Environmental Health Sciences, Columbia Mailman School of Public Health , New York, New York, 10032, United States.
Lingzhen DaiDepartment of Environmental Health, Harvard T.H. Chan School of Public Health , Boston, Massachusetts, 02115, United States.
Akin CayirDepartment of Environmental Health, Harvard T.H. Chan School of Public Health , Boston, Massachusetts, 02115, United States.
Marco Sanchez-GuerraDepartment of Environmental Health, Harvard T.H. Chan School of Public Health , Boston, Massachusetts, 02115, United States.
Hannah E LaueDepartment of Environmental Health, Harvard T.H. Chan School of Public Health , Boston, Massachusetts, 02115, United States.
Vy T NguyenDepartment of Environmental Health, Harvard T.H. Chan School of Public Health , Boston, Massachusetts, 02115, United States.
Qian DiDepartment of Environmental Health, Harvard T.H. Chan School of Public Health , Boston, Massachusetts, 02115, United States.
Allan C JustDepartment of Environmental Medicine and Public Health, Icahn School of Medicine at Mount Sinai , New York, New York, 10029, United States.
Lifang HouCenter for Population Epigenetics, Department of Preventive Medicine, Robert H. Lurie Comprehensive Cancer Center, Northwestern University Feinberg School of Medicine , Chicago, Illinois, 60611, United States.
Pantel VokonasVA Normative Aging Study, Veterans Affairs Boston Healthcare System and the Department of Medicine, Boston University School of Medicine , Boston, Massachusetts, 02118, United States.
Brent A CoullDepartment of Biostatistics, Harvard T.H. Chan School of Public Health , Boston, Massachusetts 02115, United States.
Marc G WeisskopfDepartment of Environmental Health, Harvard T.H. Chan School of Public Health , Boston, Massachusetts, 02115, United States.
Andrea A BaccarelliDepartment of Environmental Health Sciences, Columbia Mailman School of Public Health , New York, New York, 10032, United States.
Joel D SchwartzDepartment of Environmental Health, Harvard T.H. Chan School of Public Health , Boston, Massachusetts, 02115, United States.

Funding

True Metal fac coreP30ES009089 · NIEHS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI Ami R Zota · 1998 to 2026
$44.7M
Translational Research Support CoreP30ES000002 · NIEHS · HARVARD UNIVERSITY (SCH OF PUBLIC HLTH) · PI SUSAN A KORRICK · 1985 to 2026
$44.6M
Training Program in Molecular and Integrative Physiological SciencesT32HL007118 · NHLBI · HARVARD UNIVERSITY (SCH OF PUBLIC HLTH) · PI LU, QUAN · 1985 to 2025
$14.3M
Epigenetic Effects of Particles and Metals on Cardiac Health of an Aging CohortR01ES015172 · NIEHS · HARVARD SCHOOL OF PUBLIC HEALTH · PI SCHWARTZ, JOEL D · 2006 to 2015
$4.8M
Circulating microRNAs in Extracellular Vesicles, Air Particulate Pollution, and Lung Function in an Aging CohortR01ES025225 · NIEHS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI BACCARELLI, ANDREA · 2016 to 2020
$2.9M
Molecular and Epigenetic Mitochondriomics of Air Particles, Lead and CognitionR01ES021733 · NIEHS · HARVARD SCHOOL OF PUBLIC HEALTH · PI BACCARELLI, ANDREA · 2012 to 2015
$2.4M
Cardiovascular Effects of Particles:The Role of Oxidative Stress and Metal PathwR01ES014663 · NIEHS · HARVARD SCHOOL OF PUBLIC HEALTH · PI SCHWARTZ, JOEL D · 2008 to 2011
$1.9M
Prenatal Exposure to Endocrine Disrupters, DNA Methylation, and Childhood ObesityR00ES023450 · NIEHS · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI JUST, ALLAN C. · 2016 to 2018
$747k
Micro-RNA Profiling and Cardiovascular Effects of Traffic Particle ExposureR21ES020010 · NIEHS · NORTHWESTERN UNIVERSITY AT CHICAGO · PI BACCARELLI, ANDREA, HOU, LIFANG · 2011 to 2012
$443k
NHLBI NIH HHS T32 HL007118NIEHS NIH HHS P30 ES000002NIEHS NIH HHS P30 ES009089NIEHS NIH HHS R00 ES023450NIEHS NIH HHS R01 ES014663NIEHS NIH HHS R01 ES015172NIEHS NIH HHS R01 ES021733NIEHS NIH HHS R01 ES025225NIEHS NIH HHS R21 ES020010
6 · The paper itself

Abstract

The mitochondrial genome has long been implicated in age-related disease, but no studies have examined its role in the relationship of long-term fine particle (PM

Indexed as

DNA MethylationGenome, MitochondrialAgedAge FactorsAgingAir PollutantsFemaleHumansMaleParticulate MatterAir PollutantsParticulate Matter

Identifiers

PMID28636816
PMCPMC5555236

What OpenQuestion holds

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Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.