Evidence map›Paper›PMID 28636669›Full record

ArticlePloS one2017

Exploring factors associated with ART adherence and retention in care under Option B+ strategy in Malawi: A qualitative study.

Salem Gugsa, Katy Potter, Hannock Tweya, Sam Phiri, Odala Sande, Pascal Sikwese, Janet Chikonda, Gabrielle O'Malley

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed, 1 pooled it
3.6field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 1 synthesis or guideline pooled it, 54 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 3 countries.

Salem GugsaLighthouse Trust, Lilongwe, Malawi.ORCID http://orcid.org/0000-0003-3545-3117
Katy PotterInternational Training and Education Center for Health (I-TECH), University of Washington Department of Global Health, Seattle, Washington, United States of America.
Hannock TweyaLighthouse Trust, Lilongwe, Malawi.
Sam PhiriLighthouse Trust, Lilongwe, Malawi.
Odala SandeLighthouse Trust, Lilongwe, Malawi.
Pascal SikweseLighthouse Trust, Lilongwe, Malawi.
Janet ChikondaMinistry of Health, District Health Office, Lilongwe, Malawi.
Gabrielle O'MalleyInternational Training and Education Center for Health (I-TECH), University of Washington Department of Global Health, Seattle, Washington, United States of America.
Lighthouse Trust · MWUniversity of Washington · USMinistry of Health · MWUniversity of North Carolina at Chapel Hill · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Although several studies have documented challenges related to inadequate adherence to antiretroviral therapy (ART) and high loss to follow-up (LTFU) among Option B+ women, there is limited understanding of why these challenges occur and how to address them. This qualitative study examines women's experiences with ART adherence and retention in care. Between July and October 2015, in-depth interviews were conducted with 39 pregnant and lactating women who initiated ART at Bwaila Hospital in Lilongwe, Malawi. Study participants included 14 in care and 25 out of care women, according to facility records. Data were analyzed using an inductive, open-coding approach to thematic analysis. Ten of the respondents (7 out of care, 3 in-care) had stopped and re-started treatment before the interview date. One of the most important factors influencing adherence and retention was the strength of women's support systems. In contrast to women in-care, most out-of-care women lacked emotional and financial support from male partners, received minimal counseling from providers at initiation, lacked designated guardians to assist with medication refills or clinic appointments, and were highly mobile. Mobility led to difficulties in accessing treatment in new settings. The most common reasons women re-started treatment following interruptions were due to providers' counseling and encouragement and the mother's desire to be healthy. Improved counseling at initiation, active follow-up counseling, women's economic empowerment interventions, promotion of peer counseling schemes and meaningful engagement of male partners can help in addressing the identified barriers and promoting sustained retention of Option B+ women.

Indexed as

Medication AdherenceProgram DevelopmentAdultAnti-Retroviral AgentsBreast FeedingCounselingFemaleHIV InfectionsHumansInterviews as TopicMalawiQualitative ResearchYoung AdultAnti-Retroviral Agents

Identifiers

PMID28636669
PMCPMC5479573
OpenAlexW2658409203

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.