Evidence map›Paper›PMID 28636164›Full record

ArticleSmall (Weinheim an der Bergstrasse, Germany)2017

A Nanostructured Microfluidic Immunoassay Platform for Highly Sensitive Infectious Pathogen Detection.

Xu Yu, Yiqiu Xia, Yi Tang, Wen-Long Zhang, Yin-Ting Yeh, Huaguang Lu, Si-Yang Zheng

Open access · bronzeAbstract read
In one paragraph

Article in Small (Weinheim an der Bergstrasse, Germany), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 1 pooled it
4.1field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 1 synthesis or guideline pooled it, 91 citations in OpenAlex.

  1. Pooled it
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  7. Review
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  15. Microfluidic devices for detection of RNA viruses.Reviews in medical virology · 2021
    Review
  16. Review
  17. Herpesviruses in Reptiles.Frontiers in veterinary science · 2021
    Review
  18. Article
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Xu YuMicro and Nano Integrated Biosystem (MINIBio) Laboratory, Department of Biomedical Engineering, The Pennsylvania State University, N-238 Millennium Science Complex, University Park, PA, 16802, USA.
Yiqiu XiaMicro and Nano Integrated Biosystem (MINIBio) Laboratory, Department of Biomedical Engineering, The Pennsylvania State University, N-238 Millennium Science Complex, University Park, PA, 16802, USA.
Yi TangWiley Lab/Avian Virology, Department of Veterinary and Biomedical Sciences, The Pennsylvania State University, University Park, PA, 16802, USA.
Wen-Long ZhangMicro and Nano Integrated Biosystem (MINIBio) Laboratory, Department of Biomedical Engineering, The Pennsylvania State University, N-238 Millennium Science Complex, University Park, PA, 16802, USA.
Yin-Ting YehMicro and Nano Integrated Biosystem (MINIBio) Laboratory, Department of Biomedical Engineering, The Pennsylvania State University, N-238 Millennium Science Complex, University Park, PA, 16802, USA.
Huaguang LuWiley Lab/Avian Virology, Department of Veterinary and Biomedical Sciences, The Pennsylvania State University, University Park, PA, 16802, USA.
Si-Yang ZhengMicro and Nano Integrated Biosystem (MINIBio) Laboratory, Department of Biomedical Engineering, The Pennsylvania State University, N-238 Millennium Science Complex, University Park, PA, 16802, USA.
Pennsylvania State University · USMillennium Engineering and Integration (United States) · US

Funding

Integration of Flexible Micro Spring Array and High Throughput Microfluidics forDP2CA174508 · NCI · PENNSYLVANIA STATE UNIVERSITY, THE · PI ZHENG, SIYANG · 2012 to 2012
$2.2M
NCI NIH HHS DP2 CA174508
6 · The paper itself

Abstract

Rapid and simultaneous detection of multiple potential pathogens by portable devices can facilitate early diagnosis of infectious diseases, and allow for rapid and effective implementation of disease prevention and treatment measures. The development of a ZnO nanorod integrated microdevice as a multiplex immunofluorescence platform for highly sensitive and selective detection of avian influenza virus (AIV) is described. The 3D morphology and unique optical property of the ZnO nanorods boost the detection limit of the H5N2 AIV to as low as 3.6 × 10

Indexed as

AnimalsBirdsImmunoassayInfluenza A Virus, H5N1 SubtypeInfluenza A Virus, H5N2 SubtypeInfluenza in BirdsMicrofluidicsNanostructuresavian influenza virusfluorescence detectioninfectious pathogenmicrofluidic chipmultiplexed detectionZnO nanorods

Identifiers

PMID28636164
PMCPMC7169616
OpenAlexW2686586352

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.