Evidence map›Paper›PMID 28635669›Full record

ReviewViruses2017

Modulation of Human β-Defensin-1 Production by Viruses.

Lisa Kathleen Ryan, Gill Diamond

Open access · goldAbstract readReview
In one paragraph

Review in Viruses, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
1.8field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 29 citations in OpenAlex.

  1. The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians · 2019
    Trial
  2. Article
  3. Review
  4. Article
  5. Article
  6. PeerJ · 2024
    Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Journal of fungi (Basel, Switzerland) · 2021
    Article
  12. Article
  13. Antiviral Activities of Human Host Defense Peptides.Current medicinal chemistry · 2020
    Review
  14. Review
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Lisa Kathleen RyanUniversity of Florida College of Medicine, Division of Infectious Disease, Department of Medicine and Global Medicine, 1600 SW Archer Road, Box 100277, Gainesville, FL 32610, USA. Lisa.Ryan@medicine.ufl.edu.
Gill DiamondUniversity of Florida College of Dentistry, Department of Oral Biology, 1600 SW Archer Road, Box 100424, Gainesville, FL 32610, USA. gdiamond@dental.ufl.edu.
University of Florida · US

Funding

Human Beta-Defensin-1 in HSV-1 Innate ImmunityR21AI072245 · NIAID · UNIV OF MED/DENT OF NJ-NJ MEDICAL SCHOOL · PI RYAN, LISA KATHLEEN · 2007 to 2010
$434k
NIAID NIH HHS R21 AI072245
6 · The paper itself

Abstract

While initially identified as a broad-spectrum antimicrobial peptide, constitutively expressed in epithelia, human β-defensin (hBD)-1 is now recognized to have a more complex pattern of expression of its gene,

Indexed as

Host-Pathogen InteractionsImmunity, InnateAnimalsAnti-Infective Agentsbeta-DefensinsHumansMiceVirusesAnti-Infective Agentsbeta-DefensinsDEFB1 protein, humanDefb1 protein, mouseantimicrobial peptideDEFB1defensinepithelial cellsgene regulationhBD-1innate immunitymonocytesplasmacytoid dendritic cellsvirus

Identifiers

PMID28635669
PMCPMC5490828
OpenAlexW2723735803

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.