Evidence map›Paper›PMID 28635588›Full record

ArticleThe Journal of general virology2017

Genome sequence variation in the constricta strain dramatically alters the protein interaction and localization map of Potato yellow dwarf virus.

Chanyong Jang, Renyuan Wang, Joseph Wells, Fabian Leon, Mark Farman, John Hammond, Michael M Goodin

Abstract read
In one paragraph

Article in The Journal of general virology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Chanyong JangDepartment of Plant Pathology, University of Kentucky, Lexington, KY, USA.
Renyuan WangDepartment of Plant Pathology, University of Kentucky, Lexington, KY, USA.
Joseph WellsDepartment of Plant Pathology, University of Kentucky, Lexington, KY, USA.
Fabian LeonDepartment of Plant Pathology, University of Kentucky, Lexington, KY, USA.
Mark FarmanDepartment of Plant Pathology, University of Kentucky, Lexington, KY, USA.
John HammondUSDA-ARS, United States National Arboretum, Beltsville, MD, USA.
Michael M GoodinDepartment of Plant Pathology, University of Kentucky, Lexington, KY, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The genome sequence of the constricta strain of Potato yellow dwarf virus (CYDV) was determined to be 12 792 nt long and organized into seven ORFs with the gene order 3'-N-X-P-Y-M-G-L-5', which encodes the nucleocapsid, phospho, movement, matrix, glyco, and RNA-dependent RNA polymerase proteins, respectively, except for X, which is of unknown function. Cloned ORFs for each gene, except L, were used to construct a protein interaction and localization map (PILM) for this virus, which shares greater than 80 % amino acid similarity in all ORFs except X and P with the sanguinolenta strain of this species (SYDV). Protein localization patterns and interactions unique to each viral strain were identified, resulting in strain-specific PILMs. Localization of CYDV and SYDV proteins in virus-infected cells mapped subcellular loci likely to be sites of replication, morphogenesis and movement.

Indexed as

Genetic VariationHost-Pathogen InteractionsCapsicumGene OrderGenome, ViralMicroscopy, ConfocalNicotianaOpen Reading FramesRhabdoviridaeSequence Analysis, DNASolanum lycopersicumSolanum tuberosumViral ProteinsViral Proteins

Identifiers

PMID28635588
PMCPMC5656794

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.