SynthesisWorld journal of surgery2017
Evaluation of Open and Minimally Invasive Adrenalectomy: A Systematic Review and Network Meta-analysis.
Synthesis in World journal of surgery, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 52 papers, 6 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
52 citing papers in PubMed, 6 syntheses or guidelines pooled it, 105 citations in OpenAlex.
- Does Robotic Adrenalectomy Outperform Laparoscopic Approaches in Obese Patients? A Systematic Review and Subgroup Meta-Analysis of 1,107 Patients.The international journal of medical robotics + computer assisted surgery : MRCAS · 2026Pooled it
- Comparing surgical outcomes of approaches to adrenalectomy - a systematic review and network meta-analysis of randomised clinical trials.Langenbeck's archives of surgery · 2023Pooled it
- Minimally invasive adrenalectomy: a comprehensive systematic review and network meta-analysis of phase II/III randomized clinical controlled trials.Langenbeck's archives of surgery · 2022Pooled it
- Multidisciplinary practice guidelines for the diagnosis, genetic counseling and treatment of pheochromocytomas and paragangliomas.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2021Guideline
- Posterior Retroperitoneoscopic Versus Laparoscopic Transperitoneal Adrenalectomy: A Systematic Review by an Updated Meta-Analysis.World journal of surgery · 2021Pooled it
- Comparing the efficacy and safety of laparoscopic and robotic adrenalectomy: a meta-analysis and trial sequential analysis.Langenbeck's archives of surgery · 2020Pooled it
- Laparoscopic transperitoneal adrenalectomy in the large adrenal tumor from single center experience.BMC surgery · 2021Trial
- A two-centre experience with hand-assisted laparoscopic, transperitoneal laparoscopic and retroperitoneoscopic adrenalectomy.Surgical endoscopy · 2026Article
- Minimally invasive adrenalectomy for Cushing's syndrome and mild autonomous cortisol secretion: a 20-year experience from a tertiary endocrine surgery center.BMC surgery · 2026Article
- Article
- An Irish experience of robotic adrenalectomy: Transitioning from open to robotic surgery.Irish journal of medical science · 2026Article
- Indocyanine green (ICG) fluorescence in laparoscopic adrenalectomy: categorization of adrenal tumors relative to normal adrenal gland.Updates in surgery · 2026Article
- The Role of Minimally Invasive Adrenalectomy for Large Adrenal Tumors (≥6 cm): Evidence from a 10-Year Retrospective Study.Journal of clinical medicine · 2025Article
- Benefits of transitioning from transperitoneal laparoscopic to retroperitoneoscopic adrenalectomy-a single center experience.Gland surgery · 2024Article
- Impact of robotic-assisted surgery on length of hospital stay in Paris public hospitals: a retrospective analysis.Journal of robotic surgery · 2024Article
- The effect of obesity on the outcomes of laparoscopic adrenal surgery in patients with Cushing syndrome.Annals of surgical treatment and research · 2024Article
- Outcomes and Follow-Up Trends in Adrenal Leiomyosarcoma: A Comprehensive Literature Review and Case Report.Journal of clinical medicine · 2024Review
- A novel study, textbook outcome in adrenalectomy: retrospective observational study in an endocrine surgical unit.Updates in surgery · 2024Observational
- Thirty day postoperative outcomes following laparoscopic adrenalectomy for functional adrenal tumors.Surgical endoscopy · 2023Article
- Retroperitoneoscopic adrenalectomy may be superior to laparoscopic transperitoneal adrenalectomy in terms of costs and profit: a retrospective pair-matched cohort analysis.Surgical endoscopy · 2023Observational
Corrections and comments
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Authors and funding
9 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAdrenalectomy can be performed via open and various minimally invasive approaches. The aim of this systematic review was to summarize the current evidence on surgical techniques of adrenalectomy.
methodsSystematic literature searches (MEDLINE, EMBASE, Web of Science, Cochrane Library) were conducted to identify randomized controlled trials (RCTs) and controlled clinical trials (CCTs) comparing at least two surgical procedures for adrenalectomy. Statistical analyses were performed, and meta-analyses were conducted. Furthermore, an indirect comparison of RCTs and a network meta-analysis of CCTs were carried out for each outcome.
resultsTwenty-six trials (1710 patients) were included. Postoperative complication rates did not show differences for open and minimally invasive techniques. Operation time was significantly shorter for open adrenalectomy than for the robotic approach (p < 0.001). No differences were found between laparoscopic and robotic approaches. Network meta-analysis showed open adrenalectomy to be the fastest technique. Blood loss was significantly reduced in the robotic arm compared with open and laparoscopic adrenalectomy (p = 0.01). Length of hospital stay (LOS) was significantly lower after conventional laparoscopy than open adrenalectomy in CCTs (p < 0.001). Furthermore, both retroperitoneoscopic (p < 0.001) and robotic access (p < 0.001) led to another significant reduction of LOS compared with conventional laparoscopy. This difference was not consistent in RCTs. Network meta-analysis revealed the lowest LOS after retroperitoneoscopic adrenalectomy.
conclusionMinimally invasive adrenalectomy is safe and should be preferred over open adrenalectomy due to shorter LOS, lower blood loss, and equivalent complication rates. The retroperitoneoscopic access features the shortest LOS and operating time. Further high-quality RCTs are warranted, especially to compare the posterior retroperitoneoscopic and the transperitoneal robotic approach.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.