Evidence map›Paper›PMID 28634789›Full record

ArticleInternational journal of computer assisted radiology and surgery2017

Detection and grading of prostate cancer using temporal enhanced ultrasound: combining deep neural networks and tissue mimicking simulations.

Shekoofeh Azizi, Sharareh Bayat, Pingkun Yan, Amir Tahmasebi, Guy Nir, Jin Tae Kwak, Sheng Xu, Storey Wilson, Kenneth A Iczkowski, M Scott Lucia and 6 more

Open access · greenAbstract readEvaluation Study
In one paragraph

Article in International journal of computer assisted radiology and surgery, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
5.4field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 49 citations in OpenAlex.

  1. Research on ultrasound-based radiomics: a bibliometric analysis.Quantitative imaging in medicine and surgery · 2024
    Article
  2. Review
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Deep adaptive registration of multi-modal prostate images.Computerized medical imaging and graphics : the official journal of the Computerized Medical Imaging Society · 2020
    Article
  9. Improving detection of prostate cancer foci via information fusion of MRI and temporal enhanced ultrasound.International journal of computer assisted radiology and surgery · 2020
    Article
  10. Artificial intelligence (AI) and big data in cancer and precision oncology.Computational and structural biotechnology journal · 2020
    Review
  11. Article
  12. Deep neural maps for unsupervised visualization of high-grade cancer in prostate biopsies.International journal of computer assisted radiology and surgery · 2019
    Article
  13. Review
  14. Article
  15. Toward a real-time system for temporal enhanced ultrasound-guided prostate biopsy.International journal of computer assisted radiology and surgery · 2018
    Article
  16. Optimize Transfer Learning for Lung Diseases in Bronchoscopy Using a New Concept: Sequential Fine-Tuning.IEEE journal of translational engineering in health and medicine · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 6 institutions in 3 countries.

Shekoofeh AziziThe University of British Columbia, Vancouver, BC, Canada. shazizi@ece.ubc.ca.
Sharareh BayatThe University of British Columbia, Vancouver, BC, Canada.
Pingkun YanPhilips Research North America, Cambridge, MA, USA.
Amir TahmasebiPhilips Research North America, Cambridge, MA, USA.
Guy NirThe University of British Columbia, Vancouver, BC, Canada.
Jin Tae KwakSejong University, Gwangjin-Gu, Seoul, South Korea.
Sheng XuNational Institutes of Health, Bethesda, MD, USA.
Storey WilsonUniversity of Colorado, Denver, CO, USA.
Kenneth A IczkowskiUniversity of Colorado, Denver, CO, USA.
M Scott LuciaUniversity of Colorado, Denver, CO, USA.
Larry GoldenbergVancouver Prostate Centre, Vancouver, BC, Canada.
Septimiu E SalcudeanThe University of British Columbia, Vancouver, BC, Canada.
Peter A PintoNational Institutes of Health, Bethesda, MD, USA.
Bradford WoodNational Institutes of Health, Bethesda, MD, USA.
Purang AbolmaesumiThe University of British Columbia, Vancouver, BC, Canada. purang@ece.ubc.ca.
Parvin MousaviQueen's University, Kingston, ON, Canada. pmousavi@cs.queensu.ca.
University of British Columbia · CANational Institutes of Health · USUniversity of Colorado Denver · USPhilips (United States) · USQueen's University · CASejong University · KR

Funding

Center for Interventional OncologyZIDBC011242 · NCI · DIVISION OF BASIC SCIENCES - NCI · PI WOOD, BRADFORD J · 2009 to 2025
$18.7M
Prostate SectionZIABC011081 · NCI · DIVISION OF BASIC SCIENCES - NCI · PI PINTO, PETER · 2009 to 2025
$15.2M
Prostate SectionZ01BC011081 · NCI · DIVISION OF BASIC SCIENCES - NCI · PI PINTO, PETER · 2008 to 2008
$99k
Interventional OncologyZIACL040015 · CLC · CLINICAL CENTER · PI WOOD, BRADFORD · 2009 to 2025
$0k
Intramural NIH HHS Z01 BC011081
6 · The paper itself

Abstract

purposeTemporal Enhanced Ultrasound (TeUS) has been proposed as a new paradigm for tissue characterization based on a sequence of ultrasound radio frequency (RF) data. We previously used TeUS to successfully address the problem of prostate cancer detection in the fusion biopsies.

methodsIn this paper, we use TeUS to address the problem of grading prostate cancer in a clinical study of 197 biopsy cores from 132 patients. Our method involves capturing high-level latent features of TeUS with a deep learning approach followed by distribution learning to cluster aggressive cancer in a biopsy core. In this hypothesis-generating study, we utilize deep learning based feature visualization as a means to obtain insight into the physical phenomenon governing the interaction of temporal ultrasound with tissue.

resultsBased on the evidence derived from our feature visualization, and the structure of tissue from digital pathology, we build a simulation framework for studying the physical phenomenon underlying TeUS-based tissue characterization.

conclusionResults from simulation and feature visualization corroborated with the hypothesis that micro-vibrations of tissue microstructure, captured by low-frequency spectral features of TeUS, can be used for detection of prostate cancer.

Indexed as

HumansImage-Guided BiopsyImaging, Three-DimensionalMagnetic Resonance ImagingMaleNeoplasm StagingNeural Networks, ComputerProstatic NeoplasmsSensitivity and SpecificityUltrasonography, InterventionalCancer gradingDeep belief networkDeep learningProstate cancerTemporal enhanced ultrasound

Identifiers

PMID28634789
PMCPMC7900902
OpenAlexW2632480913

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.