Observational studyClinical research in cardiology : official journal of the German Cardiac Society2017
Prognostic impact of nutritional status assessed by the Controlling Nutritional Status score in patients with stable coronary artery disease undergoing percutaneous coronary intervention.
Observational study in Clinical research in cardiology : official journal of the German Cardiac Society, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers, 3 of them syntheses that pooled it.
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Who cites it
45 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Natriuretic peptides and C-reactive protein in in heart failure and malnutrition: a systematic review and meta-analysis.ESC heart failure · 2024Pooled it
- Prognostic Potential of the Controlling Nutritional Status (CONUT) Score in Predicting All-Cause Mortality and Major Adverse Cardiovascular Events in Patients With Coronary Artery Disease: A Meta-Analysis.Frontiers in nutrition · 2022Pooled it
- Ezetimibe in high-risk, previously treated statin patients: a systematic review and network meta-analysis of lipid efficacy.Clinical research in cardiology : official journal of the German Cardiac Society · 2019Pooled it
- Article
- Impact of nutritional status on outcome of patients of acute coronary syndrome.American heart journal plus : cardiology research and practice · 2026Article
- Prognostic nutritional index and geriatric nutritional risk index as predictors of in-hospital major adverse cardiovascular events after percutaneous coronary intervention in acute coronary syndrome patients: a multicenter retrospective cohort study.Frontiers in nutrition · 2026Article
- Prognostic impact of Naples prognostic score on long-term mortality in non-ST-elevation myocardial infarction.Biomarkers in medicine · 2025Article
- Article
- Role of Nutritional Status in Acute Coronary Syndrome Patients with Diabetes.Medicina (Kaunas, Lithuania) · 2025Article
- Predictive values of four nutritional indices for adverse outcomes in patients with hypertension.Clinical and experimental nephrology · 2025Article
- The Effect of Prognostic Nutritional Index in Predicting Clinical Outcomes in Valve Replacement Patients.Brazilian journal of cardiovascular surgery · 2025Article
- Association Between the Malnutrition Status and All-Cause Mortality in Patients With Moderate and Severe Aortic Stenosis: A Prospective Cohort Study.Journal of the American Heart Association · 2025Article
- The Prognostic Role of Naples Prognostic Score in Patients with Coronary Artery Disease.Journal of inflammation research · 2025Article
- Prognostic stratification in myocardial infarction using the modified CONUT score: a multidimensional biomarker from the MIMIC-IV cohort.Frontiers in cardiovascular medicine · 2025Article
- Impact of Nutritional Status and Cardiopulmonary Exercise Testing-Based Exercise Education on Long-Term Outcomes in Acute Coronary Syndrome - Insights From the Mie ACS Registry.Circulation reports · 2024Article
- The predictive ability of Controlling Nutritional Status score on in-hospital mortality in patients admitted to coronary care unit.Revista da Associacao Medica Brasileira (1992) · 2024Article
- Prevalence and Prognostic Significance of Malnutrition in Patients with Type B Aortic Dissection Undergoing Endovascular Repair.Reviews in cardiovascular medicine · 2024Article
- Malnutrition-Related Liver Steatosis, CONUT Score and Poor Clinical Outcomes in an Internal Medicine Department.Nutrients · 2024Article
- Comparative analysis of four nutritional scores predicting the incidence of MACE in older adults with acute coronary syndromes after PCI.Scientific reports · 2023Article
- Association between Malnutrition and Coronary Plaque Characteristics in Patients with Acute Coronary Syndrome: An Optical Coherence Tomography Study.Reviews in cardiovascular medicine · 2023Article
Corrections and comments
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Authors and funding
13 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundRecently, malnutrition has been shown to be related to worse clinical outcomes in patients with heart failure. However, the association between nutritional status and clinical outcomes in patients with coronary artery disease (CAD) remains unclear. We investigated the prognostic value of malnutrition assessed by the Controlling Nutritional Status (CONUT; range 0-12, higher = worse, consisting of serum albumin, cholesterol and lymphocytes) score in patients with CAD.
methodsThe CONUT score was measured on admission in a total of 1987 patients with stable CAD who underwent elective percutaneous coronary intervention (PCI) between 2000 and 2011. Patients were divided into two groups according to their CONUT score (0-1 vs. ≥2). The incidence of major adverse cardiac events (MACE), including all-cause death and non-fatal myocardial infarction, was evaluated.
resultsThe median CONUT score was 1 (interquartile range 0-2). During the median follow-up of 7.4 years, 342 MACE occurred (17.2%). Kaplan-Meier curves revealed that patients with high CONUT scores had higher rates of MACE (log-rank p < 0.0001). High CONUT scores showed a significant increase in the incidence of MACE compared with low CONUT scores, even after adjusting for confounding factors (hazard ratio: 1.64, 95% confidence interval 1.30-2.07, p < 0.0001). Adding CONUT scores to a baseline model with established risk factors improved the C-index (p = 0.02), net reclassification improvement (p = 0.004) and integrated discrimination improvement (p = 0.0003).
conclusionsNutritional status assessed by the CONUT score was significantly associated with long-term clinical outcomes in patients with CAD. Pre-PCI assessment of the CONUT score may provide useful prognostic information.
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