ArticleTherapeutic advances in endocrinology and metabolism2017
Etiological factors of short stature in children and adolescents: experience at a tertiary care hospital in Egypt.
Article in Therapeutic advances in endocrinology and metabolism, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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9 citing papers in PubMed, 37 citations in OpenAlex.
- Testosterone therapy in children and adolescents: to whom, how, when?International journal of impotence research · 2022Review
- A glimpse into the black box of celiac disease complications: a case report with a rare presentation.Przeglad gastroenterologiczny · 2021Review
- Prevalence of short stature and malnutrition among Egyptian primary school children and their coexistence with Anemia.Italian journal of pediatrics · 2020Article
- Characteristics and etiologies of short stature in children: Experience of an endocrine clinic in a Tunisian tertiary care hospital.International journal of pediatrics & adolescent medicine · 2020Article
- Quantitative ultrasound screening of bone mineral density on children with short stature.Saudi medical journal · 2020Article
- Growth disorders in children and adolescents affected by syndromes or diseases associated with neurodysfunction.Scientific reports · 2019Article
- Diagnosis of Idiopathic GHD in Children Based on Response to rhGH Treatment: The Importance of GH Provocative Tests and IGF-1.Frontiers in endocrinology · 2019Article
- Inflammatory myofibroblastic tumor of gingiva in a patient with constitutional growth delay: A rare case report.Journal of Indian Society of PeriodontologyArticle
- Etiological Profile of Short Stature in Children and Adolescents.Indian journal of endocrinology and metabolismArticle
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Authors and funding
7 authors at 2 institutions in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
backgroundAccurate anthropometric measurements and critical analysis of growth data allow the clinician to promptly recognize children with short stature. The aim of this study was to determine the frequency of etiological factors causing short stature among children referred to the pediatric endocrinology clinic of Assiut University Children's Hospital, the main tertiary care center in Upper Egypt.
methodsWe conducted this descriptive observational study from May 2012 to December 2015, to analyze 637 children (boys 354, girls 283) with short stature. Evaluation included: detailed medical history, physical examination, laboratory tests, bone age and chromosomal analysis.
resultsEndocrinological causes accounted for 26% of short stature [of them, 11.8% had growth hormone deficiency (GHD)], 63.6% had normal variants of growth [of them, 42% had familial short stature (FSS), 15.8% had constitutional growth delay (CGD) and 5.5% a combination of both]. Interestingly, celiac disease (CD) constituted 6.6% of children with short stature in our cohort.
conclusionsAlthough potentially treatable causes such as GHD, hypothyroidism and CD accounted for a considerable percentage of short stature in our study, the majority of short stature in children had normal variations of growth. Growth hormone treatment in children, however, should be promptly initiated with specific clinical indications. CD is a not uncommon cause of short stature.
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