ArticleProceedings of the National Academy of Sciences of the United States of America2017
Geospatial analysis of nonmedical vaccine exemptions and pertussis outbreaks in the United States.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 1 synthesis or guideline pooled it.
- The association between vaccine hesitancy and pertussis: a systematic review and meta-analysis.Italian journal of pediatrics · 2023Pooled it
- Ethical and policy implications of vaccinomics in the United States: community members' perspectives.Human vaccines & immunotherapeutics · 2021Trial
- Estimating the risk and spatial spread of measles in populations with high MMR uptake: Using school-household networks to understand the 2013 to 2014 outbreak in the Netherlands.PLoS medicine · 2024Article
- The importance of increasing primary vaccinations against COVID-19 in Europe.Infectious Disease Modelling · 2024Article
- Can delay discounting predict vaccine hesitancy 4-years later? A study among US young adults.Preventive medicine reports · 2023Article
- Internal and external factors affecting vaccination coverage: Modeling the interactions between vaccine hesitancy, accessibility, and mandates.PLOS global public health · 2023Article
- Hesitancy towards Childhood Vaccinations among Parents of Children with Underlying Chronic Medical Conditions in Italy.Vaccines · 2022Article
- Estimates of Presumed Population Immunity to SARS-CoV-2 by State in the United States, August 2021.Open forum infectious diseases · 2022Article
- Geographic disparities and predictors of vaccination exemptions in Florida: a retrospective study.PeerJ · 2022Article
- State-Level Variations and Factors Associated with Adult Vaccination Coverage: A Multilevel Modeling Approach.PharmacoEconomics - open · 2021Article
- Article
- The landscape of childhood vaccine exemptions in the United States.Scientific data · 2020Article
- Individual and Neighborhood Factors Associated With Failure to Vaccinate Against Influenza During Pregnancy.American journal of epidemiology · 2020Article
- Measles outbreaks and public attitudes towards vaccine exemptions: some cautions and strategies for addressing vaccine hesitancy.Human vaccines & immunotherapeutics · 2020Article
- Getting Personal: How Childhood Vaccination Policies Shape the Landscape of Vaccine Exemptions.Open forum infectious diseases · 2020Article
- Commensal Microbes Affect Host Humoral Immunity toInfection and immunity · 2019Article
- The MMR Vaccine and Autism.Annual review of virology · 2019Review
- Vaccination uptake among Australian early childhood education staff: assessing perceptions, behaviours and workplace practices.BMC infectious diseases · 2019Article
- Current landscape of nonmedical vaccination exemptions in the United States: impact of policy changes.Expert review of vaccines · 2019Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
Because of increased numbers of recorded pertussis cases in the United States, this study sought to understand the role of nonmedical vaccine exemptions and waning immunity may have had on the resurgence of pertussis in the United States at the community level. We used geospatial scan statistics, SaTScan, version 9.4, to analyze nonmedical vaccine exemptions of children entering kindergarten in 2011 and 2012 and reported pertussis cases in 2012 for children in age groups 5 years and younger and 10 to 14 years. Eight statistically significant clusters of nonmedical vaccine exemptions in kindergarteners and 11 statistically significant clusters of pertussis cases in children and adolescents were identified and geospatially linked. Forty-five percent of the counties in the study had high rates of nonmedical vaccine exemptions. The proportion of kindergarteners with nonmedical vaccine exemptions was 2.8 times larger in the identified exemption clusters. In addition, 31 counties had geographic clusters of high rates of pertussis in children ages 10 to 14 years old, consistent with waning immunity. Our findings are consistent with the view that geographic clusters of nonmedical vaccine exemptions and waning immunity may have been factors contributing to community-level pertussis outbreaks.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.