Evidence map›Paper›PMID 28634217›Full record

ArticleCirculation2017

Incident Cardiovascular Disease Among Adults With Blood Pressure <140/90 mm Hg.

Gabriel S Tajeu, John N Booth, Lisandro D Colantonio, Rebecca F Gottesman, George Howard, Daniel T Lackland, Emily C O'Brien, Suzanne Oparil, Joseph Ravenell, Monika M Safford and 6 more

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Circulation, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed, 1 pooled it
6.1field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

39 citing papers in PubMed, 1 synthesis or guideline pooled it, 74 citations in OpenAlex.

  1. Pooled it
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

16 authors at 8 institutions in 1 country.

Gabriel S TajeuFrom Department of Health Services Administration and Policy, Temple University, Philadelphia, PA (G.S.T.); Department of Epidemiology (J.N.B., L.D.C., R.M.T., P.M.), Department of Biostatistics (G.H.), Department of Medicine, Division of Cardiovascular Disease, Vascular Biology and Hypertension Program (S.O.), Department of Medicine (M.M.S.), University of Alabama at Birmingham; Department of Neurology, The Johns Hopkins University School of Medicine, Baltimore, MD (R.F.G.); Department of Neurology, Medical University of South Carolina, Charleston (D.T.L.); Duke Clinical Research Institute, Duke University, Durham, NC (E.C.O.); Department of Population Health, New York University School of Medicine (J.R., T.S.); Department of Medicine, Weill Cornell Medical College, New York (M.M.S.); Department of Mathematics and Statistics, University of West Florida, Pensacola, FL (S.R.S.); Department of Medicine (D.S.), Departments of Medicine and Epidemiology (S.S.), Columbia University, New York. gabriel.tajeu@temple.edu.
John N BoothFrom Department of Health Services Administration and Policy, Temple University, Philadelphia, PA (G.S.T.); Department of Epidemiology (J.N.B., L.D.C., R.M.T., P.M.), Department of Biostatistics (G.H.), Department of Medicine, Division of Cardiovascular Disease, Vascular Biology and Hypertension Program (S.O.), Department of Medicine (M.M.S.), University of Alabama at Birmingham; Department of Neurology, The Johns Hopkins University School of Medicine, Baltimore, MD (R.F.G.); Department of Neurology, Medical University of South Carolina, Charleston (D.T.L.); Duke Clinical Research Institute, Duke University, Durham, NC (E.C.O.); Department of Population Health, New York University School of Medicine (J.R., T.S.); Department of Medicine, Weill Cornell Medical College, New York (M.M.S.); Department of Mathematics and Statistics, University of West Florida, Pensacola, FL (S.R.S.); Department of Medicine (D.S.), Departments of Medicine and Epidemiology (S.S.), Columbia University, New York.
Lisandro D ColantonioFrom Department of Health Services Administration and Policy, Temple University, Philadelphia, PA (G.S.T.); Department of Epidemiology (J.N.B., L.D.C., R.M.T., P.M.), Department of Biostatistics (G.H.), Department of Medicine, Division of Cardiovascular Disease, Vascular Biology and Hypertension Program (S.O.), Department of Medicine (M.M.S.), University of Alabama at Birmingham; Department of Neurology, The Johns Hopkins University School of Medicine, Baltimore, MD (R.F.G.); Department of Neurology, Medical University of South Carolina, Charleston (D.T.L.); Duke Clinical Research Institute, Duke University, Durham, NC (E.C.O.); Department of Population Health, New York University School of Medicine (J.R., T.S.); Department of Medicine, Weill Cornell Medical College, New York (M.M.S.); Department of Mathematics and Statistics, University of West Florida, Pensacola, FL (S.R.S.); Department of Medicine (D.S.), Departments of Medicine and Epidemiology (S.S.), Columbia University, New York.
Rebecca F GottesmanFrom Department of Health Services Administration and Policy, Temple University, Philadelphia, PA (G.S.T.); Department of Epidemiology (J.N.B., L.D.C., R.M.T., P.M.), Department of Biostatistics (G.H.), Department of Medicine, Division of Cardiovascular Disease, Vascular Biology and Hypertension Program (S.O.), Department of Medicine (M.M.S.), University of Alabama at Birmingham; Department of Neurology, The Johns Hopkins University School of Medicine, Baltimore, MD (R.F.G.); Department of Neurology, Medical University of South Carolina, Charleston (D.T.L.); Duke Clinical Research Institute, Duke University, Durham, NC (E.C.O.); Department of Population Health, New York University School of Medicine (J.R., T.S.); Department of Medicine, Weill Cornell Medical College, New York (M.M.S.); Department of Mathematics and Statistics, University of West Florida, Pensacola, FL (S.R.S.); Department of Medicine (D.S.), Departments of Medicine and Epidemiology (S.S.), Columbia University, New York.
George HowardFrom Department of Health Services Administration and Policy, Temple University, Philadelphia, PA (G.S.T.); Department of Epidemiology (J.N.B., L.D.C., R.M.T., P.M.), Department of Biostatistics (G.H.), Department of Medicine, Division of Cardiovascular Disease, Vascular Biology and Hypertension Program (S.O.), Department of Medicine (M.M.S.), University of Alabama at Birmingham; Department of Neurology, The Johns Hopkins University School of Medicine, Baltimore, MD (R.F.G.); Department of Neurology, Medical University of South Carolina, Charleston (D.T.L.); Duke Clinical Research Institute, Duke University, Durham, NC (E.C.O.); Department of Population Health, New York University School of Medicine (J.R., T.S.); Department of Medicine, Weill Cornell Medical College, New York (M.M.S.); Department of Mathematics and Statistics, University of West Florida, Pensacola, FL (S.R.S.); Department of Medicine (D.S.), Departments of Medicine and Epidemiology (S.S.), Columbia University, New York.
Daniel T LacklandFrom Department of Health Services Administration and Policy, Temple University, Philadelphia, PA (G.S.T.); Department of Epidemiology (J.N.B., L.D.C., R.M.T., P.M.), Department of Biostatistics (G.H.), Department of Medicine, Division of Cardiovascular Disease, Vascular Biology and Hypertension Program (S.O.), Department of Medicine (M.M.S.), University of Alabama at Birmingham; Department of Neurology, The Johns Hopkins University School of Medicine, Baltimore, MD (R.F.G.); Department of Neurology, Medical University of South Carolina, Charleston (D.T.L.); Duke Clinical Research Institute, Duke University, Durham, NC (E.C.O.); Department of Population Health, New York University School of Medicine (J.R., T.S.); Department of Medicine, Weill Cornell Medical College, New York (M.M.S.); Department of Mathematics and Statistics, University of West Florida, Pensacola, FL (S.R.S.); Department of Medicine (D.S.), Departments of Medicine and Epidemiology (S.S.), Columbia University, New York.
Emily C O'BrienFrom Department of Health Services Administration and Policy, Temple University, Philadelphia, PA (G.S.T.); Department of Epidemiology (J.N.B., L.D.C., R.M.T., P.M.), Department of Biostatistics (G.H.), Department of Medicine, Division of Cardiovascular Disease, Vascular Biology and Hypertension Program (S.O.), Department of Medicine (M.M.S.), University of Alabama at Birmingham; Department of Neurology, The Johns Hopkins University School of Medicine, Baltimore, MD (R.F.G.); Department of Neurology, Medical University of South Carolina, Charleston (D.T.L.); Duke Clinical Research Institute, Duke University, Durham, NC (E.C.O.); Department of Population Health, New York University School of Medicine (J.R., T.S.); Department of Medicine, Weill Cornell Medical College, New York (M.M.S.); Department of Mathematics and Statistics, University of West Florida, Pensacola, FL (S.R.S.); Department of Medicine (D.S.), Departments of Medicine and Epidemiology (S.S.), Columbia University, New York.
Suzanne OparilFrom Department of Health Services Administration and Policy, Temple University, Philadelphia, PA (G.S.T.); Department of Epidemiology (J.N.B., L.D.C., R.M.T., P.M.), Department of Biostatistics (G.H.), Department of Medicine, Division of Cardiovascular Disease, Vascular Biology and Hypertension Program (S.O.), Department of Medicine (M.M.S.), University of Alabama at Birmingham; Department of Neurology, The Johns Hopkins University School of Medicine, Baltimore, MD (R.F.G.); Department of Neurology, Medical University of South Carolina, Charleston (D.T.L.); Duke Clinical Research Institute, Duke University, Durham, NC (E.C.O.); Department of Population Health, New York University School of Medicine (J.R., T.S.); Department of Medicine, Weill Cornell Medical College, New York (M.M.S.); Department of Mathematics and Statistics, University of West Florida, Pensacola, FL (S.R.S.); Department of Medicine (D.S.), Departments of Medicine and Epidemiology (S.S.), Columbia University, New York.
Joseph RavenellFrom Department of Health Services Administration and Policy, Temple University, Philadelphia, PA (G.S.T.); Department of Epidemiology (J.N.B., L.D.C., R.M.T., P.M.), Department of Biostatistics (G.H.), Department of Medicine, Division of Cardiovascular Disease, Vascular Biology and Hypertension Program (S.O.), Department of Medicine (M.M.S.), University of Alabama at Birmingham; Department of Neurology, The Johns Hopkins University School of Medicine, Baltimore, MD (R.F.G.); Department of Neurology, Medical University of South Carolina, Charleston (D.T.L.); Duke Clinical Research Institute, Duke University, Durham, NC (E.C.O.); Department of Population Health, New York University School of Medicine (J.R., T.S.); Department of Medicine, Weill Cornell Medical College, New York (M.M.S.); Department of Mathematics and Statistics, University of West Florida, Pensacola, FL (S.R.S.); Department of Medicine (D.S.), Departments of Medicine and Epidemiology (S.S.), Columbia University, New York.
Monika M SaffordFrom Department of Health Services Administration and Policy, Temple University, Philadelphia, PA (G.S.T.); Department of Epidemiology (J.N.B., L.D.C., R.M.T., P.M.), Department of Biostatistics (G.H.), Department of Medicine, Division of Cardiovascular Disease, Vascular Biology and Hypertension Program (S.O.), Department of Medicine (M.M.S.), University of Alabama at Birmingham; Department of Neurology, The Johns Hopkins University School of Medicine, Baltimore, MD (R.F.G.); Department of Neurology, Medical University of South Carolina, Charleston (D.T.L.); Duke Clinical Research Institute, Duke University, Durham, NC (E.C.O.); Department of Population Health, New York University School of Medicine (J.R., T.S.); Department of Medicine, Weill Cornell Medical College, New York (M.M.S.); Department of Mathematics and Statistics, University of West Florida, Pensacola, FL (S.R.S.); Department of Medicine (D.S.), Departments of Medicine and Epidemiology (S.S.), Columbia University, New York.
Samantha R SealsFrom Department of Health Services Administration and Policy, Temple University, Philadelphia, PA (G.S.T.); Department of Epidemiology (J.N.B., L.D.C., R.M.T., P.M.), Department of Biostatistics (G.H.), Department of Medicine, Division of Cardiovascular Disease, Vascular Biology and Hypertension Program (S.O.), Department of Medicine (M.M.S.), University of Alabama at Birmingham; Department of Neurology, The Johns Hopkins University School of Medicine, Baltimore, MD (R.F.G.); Department of Neurology, Medical University of South Carolina, Charleston (D.T.L.); Duke Clinical Research Institute, Duke University, Durham, NC (E.C.O.); Department of Population Health, New York University School of Medicine (J.R., T.S.); Department of Medicine, Weill Cornell Medical College, New York (M.M.S.); Department of Mathematics and Statistics, University of West Florida, Pensacola, FL (S.R.S.); Department of Medicine (D.S.), Departments of Medicine and Epidemiology (S.S.), Columbia University, New York.
Daichi ShimboFrom Department of Health Services Administration and Policy, Temple University, Philadelphia, PA (G.S.T.); Department of Epidemiology (J.N.B., L.D.C., R.M.T., P.M.), Department of Biostatistics (G.H.), Department of Medicine, Division of Cardiovascular Disease, Vascular Biology and Hypertension Program (S.O.), Department of Medicine (M.M.S.), University of Alabama at Birmingham; Department of Neurology, The Johns Hopkins University School of Medicine, Baltimore, MD (R.F.G.); Department of Neurology, Medical University of South Carolina, Charleston (D.T.L.); Duke Clinical Research Institute, Duke University, Durham, NC (E.C.O.); Department of Population Health, New York University School of Medicine (J.R., T.S.); Department of Medicine, Weill Cornell Medical College, New York (M.M.S.); Department of Mathematics and Statistics, University of West Florida, Pensacola, FL (S.R.S.); Department of Medicine (D.S.), Departments of Medicine and Epidemiology (S.S.), Columbia University, New York.
Steven SheaFrom Department of Health Services Administration and Policy, Temple University, Philadelphia, PA (G.S.T.); Department of Epidemiology (J.N.B., L.D.C., R.M.T., P.M.), Department of Biostatistics (G.H.), Department of Medicine, Division of Cardiovascular Disease, Vascular Biology and Hypertension Program (S.O.), Department of Medicine (M.M.S.), University of Alabama at Birmingham; Department of Neurology, The Johns Hopkins University School of Medicine, Baltimore, MD (R.F.G.); Department of Neurology, Medical University of South Carolina, Charleston (D.T.L.); Duke Clinical Research Institute, Duke University, Durham, NC (E.C.O.); Department of Population Health, New York University School of Medicine (J.R., T.S.); Department of Medicine, Weill Cornell Medical College, New York (M.M.S.); Department of Mathematics and Statistics, University of West Florida, Pensacola, FL (S.R.S.); Department of Medicine (D.S.), Departments of Medicine and Epidemiology (S.S.), Columbia University, New York.
Tanya M SpruillFrom Department of Health Services Administration and Policy, Temple University, Philadelphia, PA (G.S.T.); Department of Epidemiology (J.N.B., L.D.C., R.M.T., P.M.), Department of Biostatistics (G.H.), Department of Medicine, Division of Cardiovascular Disease, Vascular Biology and Hypertension Program (S.O.), Department of Medicine (M.M.S.), University of Alabama at Birmingham; Department of Neurology, The Johns Hopkins University School of Medicine, Baltimore, MD (R.F.G.); Department of Neurology, Medical University of South Carolina, Charleston (D.T.L.); Duke Clinical Research Institute, Duke University, Durham, NC (E.C.O.); Department of Population Health, New York University School of Medicine (J.R., T.S.); Department of Medicine, Weill Cornell Medical College, New York (M.M.S.); Department of Mathematics and Statistics, University of West Florida, Pensacola, FL (S.R.S.); Department of Medicine (D.S.), Departments of Medicine and Epidemiology (S.S.), Columbia University, New York.
Rikki M TannerFrom Department of Health Services Administration and Policy, Temple University, Philadelphia, PA (G.S.T.); Department of Epidemiology (J.N.B., L.D.C., R.M.T., P.M.), Department of Biostatistics (G.H.), Department of Medicine, Division of Cardiovascular Disease, Vascular Biology and Hypertension Program (S.O.), Department of Medicine (M.M.S.), University of Alabama at Birmingham; Department of Neurology, The Johns Hopkins University School of Medicine, Baltimore, MD (R.F.G.); Department of Neurology, Medical University of South Carolina, Charleston (D.T.L.); Duke Clinical Research Institute, Duke University, Durham, NC (E.C.O.); Department of Population Health, New York University School of Medicine (J.R., T.S.); Department of Medicine, Weill Cornell Medical College, New York (M.M.S.); Department of Mathematics and Statistics, University of West Florida, Pensacola, FL (S.R.S.); Department of Medicine (D.S.), Departments of Medicine and Epidemiology (S.S.), Columbia University, New York.
Paul MuntnerFrom Department of Health Services Administration and Policy, Temple University, Philadelphia, PA (G.S.T.); Department of Epidemiology (J.N.B., L.D.C., R.M.T., P.M.), Department of Biostatistics (G.H.), Department of Medicine, Division of Cardiovascular Disease, Vascular Biology and Hypertension Program (S.O.), Department of Medicine (M.M.S.), University of Alabama at Birmingham; Department of Neurology, The Johns Hopkins University School of Medicine, Baltimore, MD (R.F.G.); Department of Neurology, Medical University of South Carolina, Charleston (D.T.L.); Duke Clinical Research Institute, Duke University, Durham, NC (E.C.O.); Department of Population Health, New York University School of Medicine (J.R., T.S.); Department of Medicine, Weill Cornell Medical College, New York (M.M.S.); Department of Mathematics and Statistics, University of West Florida, Pensacola, FL (S.R.S.); Department of Medicine (D.S.), Departments of Medicine and Epidemiology (S.S.), Columbia University, New York.
Johns Hopkins Medicine · USJohns Hopkins University · USNew York University · USDuke University · USClinical Research Institute · USCornell University · USMedical University of South Carolina · USUniversity of West Florida · US

Funding

VCID and Stroke in a Bi-racial National CohortU01NS041588 · NINDS · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI CUSHMAN, MARY, HOWARD, GEORGE · 2002 to 2022
$96.0M
Institute for Clinical and Translational ResearchUL1TR001079 · NCATS · JOHNS HOPKINS UNIVERSITY · PI FORD, DANIEL ERNEST · 2013 to 2017
$60.1M
Clinical and Translational Science AwardUL1TR000040 · NCATS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI GINSBERG, HENRY N · 2012 to 2015
$26.2M
REGARDS - MI StudyR01HL080477 · NHLBI · WEILL MEDICAL COLL OF CORNELL UNIV · PI LEVITAN, EMILY B, SAFFORD, MONIKA M · 2006 to 2020
$11.6M
Understanding Cohort Effects on Stroke, VCID, and Cognition After Major Epidemiologic TransitionsR01NS041588 · NINDS · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI MARY CUSHMAN, VIRGINIA J. HOWARD · 2001 to 2026
$8.8M
MECHANISMS OF HYPERTENSION AND CARDIOVASCULAR DISEASEST32HL007457 · NHLBI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI Martin E Young · 1985 to 2026
$8.6M
Incorporation of a Hypertension Working Group into the Jackson Heart StudyR01HL117323 · NHLBI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI LEWIS, CORA E, OGEDEGBE, OLUGBENGA G. · 2013 to 2024
$7.2M
Adjunctive Use of Apyrase to Fibrinolytic TherapyR44HL095169 · NHLBI · APT THERAPEUTICS, INC. · PI CHEN, RIDONG · 2012 to 2013
$1.3M
SUBCLINICAL CARDIOVASCULAR DISEASE STUDYN01HC095166 · HC · UNIVERSITY OF VERMONT &ST AGRIC COLLEGE · PI TRACY, RUSSELL P · 1999 to 2001
$758k
SUBCLINICAL CARDIOVASCULAR DISEASE STUDY-FIELD CENTERN01HC095162 · HC · JOHNS HOPKINS UNIVERSITY · PI SZKLO, MOYSES A · 1999 to 2000
$694k
SUBCLINICAL CARDIOVASCULAR DISEASE STUDY--FIELD CENTERN01HC095161 · HC · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI SHEA, STEVEN · 1999 to 2001
$642k
SUBCLINICAL CARDIOVASCULAR DISEASE STUDY--FIELD CENTERN01HC095165 · HC · WAKE FOREST UNIVERSITY · PI BURKE, GREGORY L · 1999 to 2001
$616k
NCATS NIH HHS UL1 TR000040NCATS NIH HHS UL1 TR001079NHLBI NIH HHS HHSN268201300046CNHLBI NIH HHS HHSN268201300047CNHLBI NIH HHS HHSN268201300048CNHLBI NIH HHS HHSN268201300049CNHLBI NIH HHS HHSN268201300050CNHLBI NIH HHS HHSN268201500003CNHLBI NIH HHS HHSN268201500003INHLBI NIH HHS K24 HL125704NHLBI NIH HHS N01 HC095159NHLBI NIH HHS N01 HC095160NHLBI NIH HHS N01 HC095161NHLBI NIH HHS N01 HC095162NHLBI NIH HHS N01 HC095163NHLBI NIH HHS N01 HC095164NHLBI NIH HHS N01 HC095165NHLBI NIH HHS N01 HC095166NHLBI NIH HHS N01 HC095167NHLBI NIH HHS N01 HC095168NHLBI NIH HHS N01 HC095169NHLBI NIH HHS R01 HL080477NHLBI NIH HHS R01 HL117323NHLBI NIH HHS T32 HL007457NINDS NIH HHS R01 NS041588NINDS NIH HHS U01 NS041588
6 · The paper itself

Abstract

backgroundData from before the 2000s indicate that the majority of incident cardiovascular disease (CVD) events occur among US adults with systolic and diastolic blood pressure (SBP/DBP) ≥140/90 mm Hg. Over the past several decades, BP has declined and hypertension control has improved.

methodsWe estimated the percentage of incident CVD events that occur at SBP/DBP <140/90 mm Hg in a pooled analysis of 3 contemporary US cohorts: the REGARDS study (Reasons for Geographic and Racial Differences in Stroke), the MESA (Multi-Ethnic Study of Atherosclerosis), and the JHS (Jackson Heart Study) (n=31 856; REGARDS=21 208; MESA=6779; JHS=3869). Baseline study visits were conducted in 2003 to 2007 for REGARDS, 2000 to 2002 for MESA, and 2000 to 2004 for JHS. BP was measured by trained staff using standardized methods. Antihypertensive medication use was self-reported. The primary outcome was incident CVD, defined by the first occurrence of fatal or nonfatal stroke, nonfatal myocardial infarction, fatal coronary heart disease, or heart failure. Events were adjudicated in each study.

resultsOver a mean follow-up of 7.7 years, 2584 participants had incident CVD events. Overall, 63.0% (95% confidence interval [CI], 54.9-71.1) of events occurred in participants with SBP/DBP <140/90 mm Hg; 58.4% (95% CI, 47.7-69.2) and 68.1% (95% CI, 60.1-76.0) among those taking and not taking antihypertensive medication, respectively. The majority of events occurred in participants with SBP/DBP <140/90 mm Hg among those <65 years of age (66.7%; 95% CI, 60.5-73.0) and ≥65 years of age (60.3%; 95% CI, 51.0-69.5), women (61.4%; 95% CI, 49.9-72.9) and men (63.8%; 95% CI, 58.4-69.1), and for whites (68.7%; 95% CI, 66.1-71.3), blacks (59.0%; 95% CI, 49.5-68.6), Hispanics (52.7%; 95% CI, 45.1-60.4), and Chinese-Americans (58.5%; 95% CI, 45.2-71.8). Among participants taking antihypertensive medication with SBP/DBP <140/90 mm Hg, 76.6% (95% CI, 75.8-77.5) were eligible for statin treatment, but only 33.2% (95% CI, 32.1-34.3) were taking one, and 19.5% (95% CI, 18.5-20.5) met the SPRINT (Systolic Blood Pressure Intervention Trial) eligibility criteria and may benefit from a SBP target goal of 120 mm Hg.

conclusionsAlthough higher BP levels are associated with increased CVD risk, in the modern era, the majority of incident CVD events occur in US adults with SBP/DBP <140/90 mm Hg. While absolute risk and cost-effectiveness should be considered, additional CVD risk-reduction measures for adults with SBP/DBP <140/90 mm Hg at high risk for CVD may be warranted.

Indexed as

AgedAge FactorsAntihypertensive AgentsBlood PressureCardiovascular DiseasesCoronary Artery DiseaseFemaleFollow-Up StudiesHeart FailureHumansHydroxymethylglutaryl-CoA Reductase InhibitorsHypertensionIncidenceMaleMiddle AgedMyocardial InfarctionAntihypertensive AgentsHydroxymethylglutaryl-CoA Reductase Inhibitorscardiovascular diseasecardiovascular disease riskcerebrovascular diseaseepidemiologyheart failurehigh blood pressurehypertensionmyocardial infarctionstroke

Identifiers

PMID28634217
PMCPMC5580500
OpenAlexW2701174192

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