Evidence map›Paper›PMID 28634183›Full record

ArticleBlood2017

Syk inhibitors interfere with erythrocyte membrane modification during

Antonella Pantaleo, Kristina R Kesely, Maria Carmina Pau, Ioannis Tsamesidis, Evelin Schwarzer, Oleksii A Skorokhod, Huynh D Chien, Marta Ponzi, Lucia Bertuccini, Philip S Low and 1 more

Open access · hybridAbstract read
In one paragraph

Article in Blood, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
3.0field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 40 citations in OpenAlex.

  1. Trial
  2. bioRxiv : the preprint server for biology · 2025
    Article
  3. Review
  4. Article
  5. Article
  6. Review
  7. Article
  8. Review
  9. Review
  10. Article
  11. Novel Therapeutics for Malaria.Pharmaceutics · 2023
    Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Review
  17. Article
  18. Pathogen induced subversion of NADCell death discovery · 2021
    Article
  19. Sickle Cell Trait Modulates the Proteome and Phosphoproteome ofFrontiers in cellular and infection microbiology · 2021
    Article
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors at 6 institutions in 3 countries.

Antonella PantaleoDepartment of Biomedical Sciences, University of Sassari, Sassari, Italy.ORCID 0000-0003-2954-7053
Kristina R KeselyPurdue Center for Drug Discovery and Department of Chemistry, Purdue University, West Lafayette, IN.
Maria Carmina PauDepartment of Biomedical Sciences, University of Sassari, Sassari, Italy.
Ioannis TsamesidisDepartment of Medicine, University of Verona, Verona, Italy.ORCID 0000-0002-1439-3920
Evelin SchwarzerDepartment of Oncology, University of Turin, Turin, Italy.
Oleksii A SkorokhodDepartment of Oncology, University of Turin, Turin, Italy.
Huynh D ChienBiomedical Institute, Medical School, University of Hue, Hue City, Vietnam; and.
Marta PonziDepartment of Infectious Diseases.
Lucia BertucciniCore Facilities, and.
Philip S LowPurdue Center for Drug Discovery and Department of Chemistry, Purdue University, West Lafayette, IN.
Francesco M TurriniDepartment of Oncology, University of Turin, Turin, Italy.
University of Turin · ITPurdue University West Lafayette · USUniversity of Sassari · ITHue University · VNOffice of Infectious Diseases · USUniversity of Verona · IT

Funding

Studies of Erythrocyte Membrane StructureR01GM024417 · NIGMS · PURDUE UNIVERSITY WEST LAFAYETTE · PI LOW, PHILIP STEWART · 1985 to 2020
$5.4M
NIGMS NIH HHS R01 GM024417
6 · The paper itself

Abstract

Band 3 (also known as the anion exchanger, SLCA1, AE1) constitutes the major attachment site of the spectrin-based cytoskeleton to the erythrocyte's lipid bilayer and thereby contributes critically to the stability of the red cell membrane. During the intraerythrocytic stage of

Indexed as

AdultAnimalsAnion Exchange Protein 1, ErythrocyteCell DifferentiationErythrocyte MembraneFemaleHumansInhibitory Concentration 50Malaria, FalciparumMaleParasitesPhosphorylationPlasmodium falciparumProtein Kinase InhibitorsSyk KinaseAnion Exchange Protein 1, ErythrocyteProtein Kinase InhibitorsSyk Kinase

Identifiers

PMID28634183
PMCPMC8939463
OpenAlexW2666315598

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.