Evidence map›Paper›PMID 28634159›Full record

ArticleGenetics2017

A Role for the Nonsense-Mediated mRNA Decay Pathway in Maintaining Genome Stability in

Víctor González-Huici, Bin Wang, Anton Gartner

Open access · bronzeAbstract read
In one paragraph

Article in Genetics, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.3field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 13 citations in OpenAlex.

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  8. G3 (Bethesda, Md.) · 2017
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Víctor González-HuiciSchool of Life Sciences, Centre for Gene Regulation and Expression, University of Dundee, DD1 5EH, UK.
Bin WangSchool of Life Sciences, Centre for Gene Regulation and Expression, University of Dundee, DD1 5EH, UK.
Anton GartnerSchool of Life Sciences, Centre for Gene Regulation and Expression, University of Dundee, DD1 5EH, UK a.gartner@dundee.ac.uk.
University of Dundee · GB

Funding

Enhancing and expanding the CGC Strain CollectionP40OD010440 · OD · UNIVERSITY OF MINNESOTA · PI Ann E. Rougvie · 2012 to 2026
$7.5M
Cancer Research UK 14695Medical Research Council MR/K015869/1NIH HHS P40 OD010440Wellcome TrustWellcome Trust 0909444/Z/09/ZWellcome Trust 097045/B/11/ZWellcome Trust 097945/B/11/Z
6 · The paper itself

Abstract

Ionizing radiation (IR) is commonly used in cancer therapy and is a main source of DNA double-strand breaks (DSBs), one of the most toxic forms of DNA damage. We have used

Indexed as

Genomic InstabilityNonsense Mediated mRNA DecayAnimalsCaenorhabditis elegansCaenorhabditis elegans ProteinsDNA Breaks, Double-StrandedDNA DamageDNA RepairEpistasis, GeneticHomologous RecombinationMitosisProtein Serine-Threonine KinasesRadiation, IonizingCaenorhabditis elegans ProteinsProtein Serine-Threonine KinasesSMG-1 protein, C elegansdouble-strand-break repairionizing radiationmitosisnonsense-mediated mRNA decaytranscription-replication interface

Identifiers

PMID28634159
PMCPMC5560793
OpenAlexW2711672469

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.