ArticlePharmaceutical biology2017
Variation of alkaloid contents and antimicrobial activities of Papaver rhoeas L. growing in Turkey and northern Cyprus.
Article in Pharmaceutical biology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed, 43 citations in OpenAlex.
- Modeling of Sensory Properties of Poppy Sherbet by Turkish Consumers and Changes in Quality Properties during Storage Process.Foods (Basel, Switzerland) · 2023Article
- Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society · 2023Article
- Total Phenolic Content and Antioxidant and Antimicrobial Activities ofMolecules (Basel, Switzerland) · 2022Article
- Review
- Ethyl Acetate Fractions ofAntioxidants (Basel, Switzerland) · 2021Article
- Alkaloid profiling and antimicrobial activities of Papaver glaucum and P. decaisnei.BMC research notes · 2021Article
- Phytomedicine from Middle Eastern Countries: An Alternative Remedy to Modern Medicine againstEvidence-based complementary and alternative medicine : eCAM · 2021Review
- Mineral Composition and Antioxidant Potential in the Common Poppy (Papaver rhoeas L.) Petal Infusions.Biological trace element research · 2021Article
- Tackling Antibiotic Resistance with Compounds of Natural Origin: A Comprehensive Review.Biomedicines · 2020Review
- Antiproliferative Properties ofMolecules (Basel, Switzerland) · 2020Article
- Antimicrobial Activity of Polyphenols and Alkaloids in Middle Eastern Plants.Frontiers in microbiology · 2019Review
- Transcriptome Profiling of Two Ornamental and MedicinalInternational journal of molecular sciences · 2018Article
- Identification and metabolite profiling of alkaloids in aerial parts of Papaver rhoeas by liquid chromatography coupled with quadrupole time-of-flight tandem mass spectrometry.Journal of separation science · 2018Article
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Authors and funding
5 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
contextPapaver rhoeas L. (Papaveraceae) corn poppy, widely distributed in Turkey, is used to make a cough syrup for children, as a tea for disturbed sleep, for pain relief and as a sedative in folk medicine.
objectiveSamples of P. rhoeas collected from eight different locations in Turkey and three from northern Cyprus were investigated for their alkaloid content and screened for their antimicrobial activities. MATERIALS AND
methodsFrom the aerial parts of P. rhoeas samples, alkaloids were isolated by column and preparative thin-layer chromatography. The alkaloids were identified by comparing their spectral data (UV, IR and
resultsTwelve different alkaloids belonging to proaporphine (mecambrine), aporphine (roemerine), promorphinan (salutaridine), protopine (coulteropine and protopine) and rhoeadine (epiglaucamine, glaucamine, glaudine, isorhoeadine, isorhoeagenine, rhoeadine and rhoeagenine) groups were isolated. The most significant activity was observed with the alkaloid extract of P8 against Staphylococcus aureus with a MIC value of 1.22 μg/mL and against Candida albicans with a MIC value of 2.4 μg/mL. DISCUSSION: The results indicate that P. rhoeas samples (P8 and P9), which contain roemerine as their major alkaloid, were the most active extracts.
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