Evidence map›Paper›PMID 28632967›Full record

ArticleMuscle & nerve2018

Prevalence and orthopedic management of foot and ankle deformities in Charcot-Marie-Tooth disease.

Matilde Laurá, Dishan Singh, Gita Ramdharry, Jasper Morrow, Mariola Skorupinska, Davide Pareyson, Joshua Burns, Richard A Lewis, Steven S Scherer, David N Herrmann and 13 more

Open access · hybridAbstract read
In one paragraph

Article in Muscle & nerve, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed, 1 pooled it
1.7field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 1 synthesis or guideline pooled it, 73 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Charcot-Marie-Tooth disease and related neuropathies.Nature reviews. Disease primers · 2026
    Review
  4. Article
  5. Inherited Peripheral Neuropathies.Neurologic clinics · 2025
    Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Review
  15. Incidence and risk factors for patellofemoral dislocation in adults with Charcot-Marie-Tooth disease: An observational study.Physiotherapy research international : the journal for researchers and clinicians in physical therapy · 2023
    Article
  16. Article
  17. Review
  18. Article
  19. Charcot-Marie-Tooth neuropathy score and ambulation index are both predictors of orthotic need for patients with CMT.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2022
    Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

23 authors at 15 institutions in 4 countries.

Matilde LauráMedical Research Council Centre for Neuromuscular Diseases, University College London Institute of Neurology, Queen Square, London, WC1N 3BG, UK.
Dishan SinghFoot and ankle unit, Royal National Orthopedic Hospital, Stanmore, UK.
Gita RamdharrySchool of Rehabilitation Sciences, St George's University of London/Kingston University, London, UK.
Jasper MorrowMedical Research Council Centre for Neuromuscular Diseases, University College London Institute of Neurology, Queen Square, London, WC1N 3BG, UK.
Mariola SkorupinskaMedical Research Council Centre for Neuromuscular Diseases, University College London Institute of Neurology, Queen Square, London, WC1N 3BG, UK.
Davide PareysonDepartment of Neurology, IRCCS Foundation, Carlo Besta Neurological Institute, Milan, Italy.
Joshua BurnsFaculty of Health Sciences, University of Sydney & Children's Hospital at Westmead, Sydney, New South Wales, Australia.
Richard A LewisDepartment of Neurology, Cedars Sinai Medical Center, West Hollywood, California, USA.
Steven S SchererDepartment of Neurology, Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania, USA.
David N HerrmannDepartment of Neurology, University of Rochester, Rochester, New York.
Nicholas CullenFoot and ankle unit, Royal National Orthopedic Hospital, Stanmore, UK.
Christopher BradishOrthopaedic and Spinal Surgery Unit, Great Ormond Street Hospital, London, UK.
Luca GaianiDepartment of Orthopaedics, ASL, Imola, Italy.
Nicolò MartinelliDepartment of Ankle and Foot Surgery, IRCCS Galeazzi, Milan, Italy.
Paul GibbonsFaculty of Health Sciences, University of Sydney & Children's Hospital at Westmead, Sydney, New South Wales, Australia.
Glenn PfefferDepartment of Neurology, Cedars Sinai Medical Center, West Hollywood, California, USA.
Phinit PhisitkulDepartment of Orthopaedic and Rehabilitation, University of Iowa Health Care, Iowa City, Iowa, USA.
Keith WapnerDepartment of Orthopaedics, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
James SandersDepartment of Orthopaedics, University of Rochester, Rochester, New York, USA.
Sam FlemisterDepartment of Orthopaedics, University of Rochester, Rochester, New York, USA.
Michael E ShyDepartment of Neurology, University of Iowa health Care, Iowa City, Iowa, USA.
Mary M ReillyMedical Research Council Centre for Neuromuscular Diseases, University College London Institute of Neurology, Queen Square, London, WC1N 3BG, UK.
Inherited Neuropathies Consortium
University of Rochester · USCedars-Sinai Medical Center · USMedical Research Council · GBRoyal National Orthopaedic Hospital · GBUniversity College London · GBUniversity of Iowa Health Care · USChildren's Hospital at Westmead · AUFondazione IRCCS Istituto Neurologico Carlo Besta · ITHospital of the University of Pennsylvania · USIstituto Ortopedico Galeazzi · ITKingston University · GBNational Hospital for Neurology and Neurosurgery · GBSacmi (Italy) · ITUniversity of Pennsylvania · USUniversity of Sydney · AU

Funding

trainingU54NS065712 · NINDS · WAYNE STATE UNIVERSITY · PI SHY, MICHAEL E. · 2009 to 2023
$19.6M
Department of Health CAT CL09-21Medical Research Council G0601943NINDS NIH HHS U54 NS065712
6 · The paper itself

Abstract

introductionFoot deformities are frequent complications in Charcot-Marie-Tooth disease (CMT) patients, often requiring orthopedic surgery. However, there are no prospective, randomized studies on surgical management, and there is variation in the approaches among centers both within and between countries.

methodsIn this study we assessed the frequency of foot deformities and surgery among patients recruited into the Inherited Neuropathies Consortium (INC). We also designed a survey addressed to orthopedic surgeons at INC centers to determine whether surgical approaches to orthopedic complications in CMT are variable.

resultsFoot deformities were reported in 71% of CMT patients; 30% of the patients had surgery. Survey questions were answered by 16 surgeons working in different specialized centers. Most of the respondents were foot and ankle surgeons. There was marked variation in surgical management. DISCUSSION: Our findings confirm that the approaches to orthopedic management of CMT are varied. We identify areas that require further research. Muscle Nerve 57: 255-259, 2018.

Indexed as

AdolescentAdultAgedAged, 80 and overAnkleAttitude of Health PersonnelCharcot-Marie-Tooth DiseaseChildChild, PreschoolFemaleFoot Deformities, CongenitalHumansInfantMaleMiddle AgedOrthopedic ProceduresCharcot-Marie-Tooth diseasefoot deformitiesfoot surgeryorthopedic complicationspes cavussurvey

Identifiers

PMID28632967
PMCPMC5811923
OpenAlexW2690187400

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.