Evidence map›Paper›PMID 28631995›Full record

ArticleFly2017

Monitoring the effect of pathogenic nematodes on locomotion of Drosophila larvae.

Martin Kunc, Badrul Arefin, Pavel Hyrsl, Ulrich Theopold

Abstract read
In one paragraph

Article in Fly, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Effect of entomopathogenic nematode ofJournal of parasitic diseases : official organ of the Indian Society for Parasitology · 2018
    Article
  4. The Immune Phenotype of ThreeG3 (Bethesda, Md.) · 2017
    Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Martin Kunca Department of Molecular Biosciences, The Wenner-Gren Institute (MBW) , Stockholm University , Stockholm , Sweden.
Badrul Arefina Department of Molecular Biosciences, The Wenner-Gren Institute (MBW) , Stockholm University , Stockholm , Sweden.ORCID 0000-0003-1117-9125
Pavel Hyrslb Department of Animal Physiology and Immunology, Institute of Experimental Biology, Faculty of Science , Masaryk University , Brno , Czech Republic.
Ulrich Theopolda Department of Molecular Biosciences, The Wenner-Gren Institute (MBW) , Stockholm University , Stockholm , Sweden.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

One of the key factors that determine the interaction between hosts and their parasites is the frequency of their interactions, which depends on the locomotory behavior of both parts. To address host behavior we used natural infections involving insect pathogenic nematodes and Drosophila melanogaster larvae as hosts. Using a modified version of a recently described method (FIMTrack) to assess several parameters in larger sets of animals, we initially detected specific differences in larval food searching when comparing Drosophila strains. These differences were further influenced by the presence of nematodes. Given a choice, Drosophila larvae clearly avoided nematodes irrespective of their genetic background. Our newly developed methods will be useful to test candidate genes and pathways involved in host/pathogen interactions in general and to assess specific parameters of their interaction.

Indexed as

AnimalsDrosophila melanogasterFeeding BehaviorGene Expression Regulation, DevelopmentalHost-Parasite InteractionsLarvaLocomotionRhabditidabehaviorDrosophila melanogasterentomopathogenic nematodesFIMTracklocomtionnematode

Identifiers

PMID28631995
PMCPMC5552269

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.