ArticleJournal of neuroscience research2017
Mild metabolic perturbations alter succinylation of mitochondrial proteins.
Article in Journal of neuroscience research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
What it found
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The trial behind it
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Who cites it
24 citing papers in PubMed.
- SIRT7-Mediated H2BK120 Succinylation Drives Aberrant Mitophagy in Sepsis-Associated Cognitive Dysfunction.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Succinylation regulates boar sperm linear motility via reprogramming glucose metabolism.Communications biology · 2025Article
- Emerging roles of mitochondrial sirtuin SIRT5 in succinylation modification and cancer development.Frontiers in immunology · 2025Review
- The metabolic-epigenetic interface: lysine succinylation orchestrates bidirectional crosstalk in neurodegenerative disorders.Frontiers in neurology · 2025Review
- De-succinylation-induced accumulation of TRMT10C in the nucleus plays a detrimental role in coronary microembolization via its m1A modification function.International journal of biological sciences · 2025Article
- Succinylation modification: a potential therapeutic target in stroke.Neural regeneration research · 2024Review
- Comprehensive analysis of the gut microbiome and post-translational modifications elucidates the route involved in microbiota-host interactions.Zoological research · 2024Article
- Protein succinylation: regulating metabolism and beyond.Frontiers in nutrition · 2024Review
- Defective function of α-ketoglutarate dehydrogenase exacerbates mitochondrial ATP deficits during complex I deficiency.Redox biology · 2023Article
- Ischemic accumulation of succinate induces Cdc42 succinylation and inhibits neural stem cell proliferation after cerebral ischemia/reperfusion.Neural regeneration research · 2023Article
- Post-translational modifications and their implications in cancer.Frontiers in oncology · 2023Review
- The α-Ketoglutarate Dehydrogenase Complex as a Hub of Plasticity in Neurodegeneration and Regeneration.International journal of molecular sciences · 2022Review
- Protein Succinylation and Malonylation as Potential Biomarkers in Schizophrenia.Journal of personalized medicine · 2022Article
- Altered succinylation of mitochondrial proteins, APP and tau in Alzheimer's disease.Nature communications · 2022Article
- Preparation of Site-Specific Succinylated Histone Mimics to Investigate Its Impact on Nucleosome Dynamics.Methods in molecular biology (Clifton, N.J.) · 2022Article
- Insights into the post-translational modification and its emerging role in shaping the tumor microenvironment.Signal transduction and targeted therapy · 2021Review
- The Mystery of Extramitochondrial Proteins Lysine Succinylation.International journal of molecular sciences · 2021Review
- Selective linkage of mitochondrial enzymes to intracellular calcium stores differs between human-induced pluripotent stem cells, neural stem cells, and neurons.Journal of neurochemistry · 2021Article
- Role of succinylation modification in thyroid cancer and breast cancer.American journal of cancer research · 2021Review
- Semisynthesis of site-specifically succinylated histone reveals that succinylation regulates nucleosome unwrapping rate and DNA accessibility.Nucleic acids research · 2020Article
Corrections and comments
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Authors and funding
8 authors.
Funding
Abstract
Succinylation of proteins is widespread, modifies both the charge and size of the molecules, and can alter their function. For example, liver mitochondrial proteins have 1,190 unique succinylation sites representing multiple metabolic pathways. Succinylation is sensitive to both increases and decreases of the NAD
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Registered trials
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