Evidence map›Paper›PMID 28631612›Full record

ArticleeLife2017

Nicole L Nuckolls, María Angélica Bravo Núñez, Michael T Eickbush, Janet M Young, Jeffrey J Lange, Jonathan S Yu, Gerald R Smith, Sue L Jaspersen, Harmit S Malik, Sarah E Zanders

Open access · goldAbstract read
In one paragraph

Article in eLife, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 88 papers.

0numbers the graph read from it
0cells of the map it votes in
88citing papers in PubMed
6.8field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

88 citing papers in PubMed, 144 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. The long reach of the Red Queen.Nature reviews. Genetics · 2026
    Article
  5. Article
  6. Review
  7. Article
  8. The evolutionary genomics of meiotic drive.Molecular biology and evolution · 2026
    Article
  9. Oocyte Kinetochores at the Nexus of Meiotic Drive and Segregation Fidelity.Advances in experimental medicine and biology · 2026
    Review
  10. Evolutionary persistence and divergence of thebioRxiv : the preprint server for biology · 2025
    Article
  11. Article
  12. Article
  13. Review
  14. Article
  15. Article
  16. Article
  17. Review
  18. Article
  19. Functional constraints ofbioRxiv : the preprint server for biology · 2025
    Article
  20. Article

28 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Nicole L NuckollsStowers Institute for Medical Research, Kansas City, United States.
María Angélica Bravo NúñezStowers Institute for Medical Research, Kansas City, United States.
Michael T EickbushStowers Institute for Medical Research, Kansas City, United States.
Janet M YoungDivision of Basic Sciences, Fred Hutchinson Cancer Research Center, Seattle, United States.ORCID 0000-0001-8220-8427
Jeffrey J LangeStowers Institute for Medical Research, Kansas City, United States.
Jonathan S YuDivision of Basic Sciences, Fred Hutchinson Cancer Research Center, Seattle, United States.
Gerald R SmithDivision of Basic Sciences, Fred Hutchinson Cancer Research Center, Seattle, United States.
Sue L JaspersenStowers Institute for Medical Research, Kansas City, United States.
Harmit S MalikDivision of Basic Sciences, Fred Hutchinson Cancer Research Center, Seattle, United States.ORCID 0000-0001-6005-0016
Sarah E ZandersStowers Institute for Medical Research, Kansas City, United States.ORCID 0000-0003-1867-986X
Stowers Institute for Medical Research · USFred Hutch Cancer Center · USHoward Hughes Medical Institute · US

Funding

MOLECULAR ANALYSIS OF HOTSPOTS OF GENETIC RECOMBINATIONR01GM031693 · NIGMS · FRED HUTCHINSON CANCER RESEARCH CENTER · PI SMITH, GERALD R · 1985 to 2015
$9.7M
Molecular analysis of genetic recombination and DNA break repairR35GM118120 · NIGMS · FRED HUTCHINSON CANCER RESEARCH CENTER · PI SMITH, GERALD R · 2016 to 2025
$9.3M
Genetic Conflict Shapes Centromeres and HeterochromatinR01GM074108 · NIGMS · FRED HUTCHINSON CANCER RESEARCH CENTER · PI MALIK, HARMIT S. · 2005 to 2022
$6.1M
Models of Selfishness: Molecular and Evolutionary Analyses of the Wtf Meiotic DriversDP2GM132936 · NIGMS · STOWERS INSTITUTE FOR MEDICAL RESEARCH · PI ZANDERS, SARAH ELIZABETH · 2018 to 2018
$2.5M
Mechanisms of meiotic drive and the functional consequences of rapid genome evolutionR00GM114436 · NIGMS · STOWERS INSTITUTE FOR MEDICAL RESEARCH · PI ZANDERS, SARAH ELIZABETH · 2016 to 2018
$747k
Mechanisms of meiotic drive and the functional consequences of rapid genome evolution in SchizosaccharomycesK99GM114436 · NIGMS · FRED HUTCHINSON CANCER RESEARCH CENTER · PI ZANDERS, SARAH ELIZABETH · 2015 to 2016
$112k
Howard Hughes Medical InstituteNIGMS NIH HHS DP2 GM132936NIGMS NIH HHS K99 GM114436NIGMS NIH HHS R00 GM114436NIGMS NIH HHS R01 GM031693NIGMS NIH HHS R01 GM074108NIGMS NIH HHS R35 GM118120
6 · The paper itself

Abstract

Meiotic drivers are selfish genes that bias their transmission into gametes, defying Mendelian inheritance. Despite the significant impact of these genomic parasites on evolution and infertility, few meiotic drive loci have been identified or mechanistically characterized. Here, we demonstrate a complex landscape of meiotic drive genes on chromosome 3 of the fission yeasts

Indexed as

Genes, FungalMeiosisSelection, GeneticAntidotesBiological ProductsPoisonsSchizosaccharomycesAntidotesBiological ProductsPoisonschromosomesevolutionevolutionary biologygenesgenetic conflictgenomicsinfertilitymeiosisMeiotic driveselfish genesS. pombe

Identifiers

PMID28631612
PMCPMC5478261
OpenAlexW2648124781

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.