Evidence map›Paper›PMID 28631578›Full record

ReviewDevelopment and psychopathology2018

The journey to autism: Insights from neuroimaging studies of infants and toddlers.

Jason J Wolff, Suma Jacob, Jed T Elison

Abstract readReview
In one paragraph

Review in Development and psychopathology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 53 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
53citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

53 citing papers in PubMed, 4 syntheses or guidelines pooled it.

  1. Pooled it
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  5. Efficacy and Safety of AltibrainCurrent pharmaceutical design · 2025
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  7. Social communication development in a contingent world: insights from autism.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Jason J WolffUniversity of Minnesota.ORCID https://orcid.org/0000-0003-4300-8195
Suma JacobUniversity of Minnesota.
Jed T ElisonUniversity of Minnesota.

Funding

Infant Brain and Behavioral Signatures of Later Emerging Risk for PsychopathologyR01MH104324 · NIMH · UNIVERSITY OF MINNESOTA · PI ELISON, JED THOMAS · 2014 to 2018
$2.6M
Brain Imaging Markers of Response to Intervention in Toddlers with AutismK01MH101653 · NIMH · UNIV OF NORTH CAROLINA CHAPEL HILL · PI WOLFF, JASON J · 2013 to 2017
$651k
NIMH NIH HHS K01 MH101653NIMH NIH HHS R01 MH104324
6 · The paper itself

Abstract

By definition, autism spectrum disorder (ASD) is a neurodevelopmental disorder that emerges during early childhood. It is during this time that infants and toddlers transition from appearing typical across multiple domains to exhibiting the behavioral phenotype of ASD. Neuroimaging studies focused on this period of development have provided crucial knowledge pertaining to this process, including possible mechanisms underlying pathogenesis of the disorder and offering the possibility of prodromal or presymptomatic prediction of risk. In this paper, we review findings from structural and functional brain imaging studies of ASD focused on the first years of life and discuss implications for next steps in research and clinical applications.

Indexed as

Autism Spectrum DisorderBrainNeuroimagingHumansInfant

Identifiers

PMID28631578
PMCPMC5834406

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.