Trial reportProbiotics and antimicrobial proteins2018
Lactobacillus salivarius NK02: a Potent Probiotic for Clinical Application in Mouthwash.
Trial report in Probiotics and antimicrobial proteins, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed, 1 synthesis or guideline pooled it, 67 citations in OpenAlex.
- Pooled it
- Trial
- Probiotic strains of Lactobacillus brevis and Lactobacillus plantarum as adjunct to non-surgical periodontal therapy: 3-month results of a randomized controlled clinical trial.Clinical oral investigations · 2021Trial
- Effect of bovine milk fermented with Lactobacillus rhamnosus L8020 on periodontal disease in individuals with intellectual disability: a randomized clinical trial.Journal of applied oral science : revista FOB · 2019Trial
- Article
- Probiotics as an adjunctive therapy in periodontitis treatment-reality or illusion-a clinical perspective.NPJ biofilms and microbiomes · 2024Review
- The impact of prebiotics and probiotics on the oral microbiome of individuals with periodontal disease: a scoping review.Canadian journal of dental hygiene : CJDH = Journal canadien de l'hygiene dentaire : JCHD · 2024Article
- UnderstandingFoods (Basel, Switzerland) · 2024Review
- Mouthwash Effects on the Oral Microbiome: Are They Good, Bad, or Balanced?International dental journal · 2023Review
- Mouthwashes: Alternatives and Future Directions.International dental journal · 2023Review
- The increasing importance of the oral microbiome in periodontal health and disease.Future science OA · 2023Review
- Enhanced antimicrobial activity of lactic acid bacteria through genome shuffling and genetic variability among shuffled strains.World journal of microbiology & biotechnology · 2023Article
- Novel Dietary Approach with Probiotics, Prebiotics, and Synbiotics to Mitigate Antimicrobial Resistance and Subsequent Out Marketplace of Antimicrobial Agents: A Review.Infection and drug resistance · 2023Review
- The rationale and potential for using Lactobacillus in the management of periodontitis.Journal of microbiology (Seoul, Korea) · 2022Review
- Probiotic Species in the Management of Periodontal Diseases: An Overview.Frontiers in cellular and infection microbiology · 2022Review
- Probiotics-Containing Mucoadhesive Gel for Targeting the Dysbiosis Associated with Periodontal Diseases.International journal of dentistry · 2022Article
- Probiotics During the Therapeutic Management of Periodontitis.Advances in experimental medicine and biology · 2022Review
- Pre and Probiotics Involved in the Modulation of Oral Bacterial Species: New Therapeutic Leads in Mental Disorders?Microorganisms · 2021Review
- Tapioca Starch Modulates Cellular Events in Oral Probiotic Streptococcus salivarius Strains.Probiotics and antimicrobial proteins · 2021Article
- The role of the oral microbiota in chronic non-communicable disease and its relevance to the Indigenous health gap in Australia.BMC oral health · 2020Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 4 institutions in 1 country.
Funding
Abstract
A specific strain of naturally occurring oral lactobacilli was isolated and identified based on morphological, biochemical, and 16S rRNA gene sequencing. The phylogenetic affiliation of the isolate confirmed that the NK02 strain had close association with the Lactobacillus salivarius. An effective mouthwash was developed for treatment of periodontitis and suppression of the indicator bacterium Aggregatibacter actinomycetemcomitans which is an obvious pathogen of periodontal disease. The mouthwash containing L. salivarius NK02 was tested at a dose level of 10
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.