Evidence map›Paper›PMID 28631147›Full record

ArticleExperimental brain research2017

The motor cortical representation of a muscle is not homogeneous in brain connectivity.

Jo Armour Smith, Alaa Albishi, Sarine Babikian, Skulpan Asavasopon, Beth E Fisher, Jason J Kutch

Abstract read
PubMed Publisher
In one paragraph

Article in Experimental brain research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.5field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 11 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 2 countries.

Jo Armour SmithDivision of Biokinesiology and Physical Therapy, University of Southern California, Los Angeles, CA, USA.
Alaa AlbishiDivision of Biokinesiology and Physical Therapy, University of Southern California, Los Angeles, CA, USA.
Sarine BabikianDepartment of Mechanical Engineering, University of Southern California, Los Angeles, CA, USA.
Skulpan AsavasoponDivision of Biokinesiology and Physical Therapy, University of Southern California, Los Angeles, CA, USA.
Beth E FisherDivision of Biokinesiology and Physical Therapy, University of Southern California, Los Angeles, CA, USA.
Jason J KutchDivision of Biokinesiology and Physical Therapy, University of Southern California, Los Angeles, CA, USA. kutch@usc.edu.ORCID 0000-0002-2417-4879
University of Southern California · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Functional connectivity patterns of the motor cortical representational area of single muscles have not been extensively mapped in humans, particularly for the axial musculature. Functional connectivity may provide a neural substrate for adaptation of muscle activity in axial muscles that have both voluntary and postural functions. The purpose of this study was to combine brain stimulation and neuroimaging to both map the cortical representation of the external oblique (EO) in primary motor cortex (M1) and supplementary motor area (SMA), and to establish the resting-state functional connectivity associated with this representation. Motor-evoked potentials were elicited from the EO muscle in stimulation locations encompassing M1 and SMA. The coordinates of locations with the largest motor-evoked potentials were confirmed with task-based fMRI imaging during EO activation. The M1 and SMA components of the EO representation demonstrated significantly different resting-state functional connectivity with other brain regions: the SMA representation of the EO muscle was significantly more connected to the putamen and cerebellum, and the M1 representation of the EO muscle was significantly more connected to somatosensory cortex and the superior parietal lobule. This study confirms the representation of a human axial muscle in M1 and SMA, and demonstrates for the first time that different parts of the cortical representation of a human axial muscle have resting-state functional connectivity with distinct brain regions. Future studies can use the brain regions of interest we have identified here to test the association between resting-state functional connectivity and control of the axial muscles.

Indexed as

Abdominal Oblique MusclesAdultBrain MappingEvoked Potentials, MotorFemaleHumansMagnetic Resonance ImagingMaleMotor CortexTranscranial Magnetic StimulationYoung AdultFunctional connectivityPrimary motor cortexSupplementary motor areaTranscranial magnetic stimulation

Identifiers

PMID28631147
OpenAlexW2696652523

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.