Evidence map›Paper›PMID 28631109›Full record

ReviewForensic science, medicine, and pathology2017

Increasing the reach of forensic genetics with massively parallel sequencing.

Bruce Budowle, Sarah E Schmedes, Frank R Wendt

Abstract readReview
PubMed Publisher
In one paragraph

Review in Forensic science, medicine, and pathology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
4.2field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 34 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Application of Microbiome in Forensics.Genomics, proteomics & bioinformatics · 2023
    Review
  5. Article
  6. Article
  7. Review
  8. Review
  9. Article
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Bruce BudowleCenter for Human Identification, University of North Texas Health Science Center, 3500 Camp Bowie Blvd, CBH-250, Fort Worth, TX, 76107, USA. bruce.budowle@unthsc.edu.
Sarah E SchmedesCenter for Human Identification, University of North Texas Health Science Center, 3500 Camp Bowie Blvd, CBH-250, Fort Worth, TX, 76107, USA.
Frank R WendtCenter for Human Identification, University of North Texas Health Science Center, 3500 Camp Bowie Blvd, CBH-250, Fort Worth, TX, 76107, USA.
University of North Texas · USUniversity of North Texas Health Science Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The field of forensic genetics has made great strides in the analysis of biological evidence related to criminal and civil matters. More so, the discipline has set a standard of performance and quality in the forensic sciences. The advent of massively parallel sequencing will allow the field to expand its capabilities substantially. This review describes the salient features of massively parallel sequencing and how it can impact forensic genetics. The features of this technology offer increased number and types of genetic markers that can be analyzed, higher throughput of samples, and the capability of targeting different organisms, all by one unifying methodology. While there are many applications, three are described where massively parallel sequencing will have immediate impact: molecular autopsy, microbial forensics and differentiation of monozygotic twins. The intent of this review is to expose the forensic science community to the potential enhancements that have or are soon to arrive and demonstrate the continued expansion the field of forensic genetics and its service in the investigation of legal matters.

Indexed as

Forensic GeneticsHigh-Throughput Nucleotide SequencingSequence Analysis, DNABioterrorismCytochrome P-450 CYP2D6DNA, BacterialHumansMicrobiotaPharmacogenomic VariantsPolymorphism, Single NucleotideTwins, MonozygoticCytochrome P-450 CYP2D6DNA, BacterialForensic geneticsMassively parallel sequencingMicrobial forensicsMolecular autopsyMonozygotic twins

Identifiers

PMID28631109
OpenAlexW2711668435

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.