Evidence map›Paper›PMID 28631080›Full record

ArticleEuropean radiology2017

Comparison of volumetric and functional parameters in simultaneous cardiac PET/MR: feasibility of volumetric assessment with residual activity from prior PET/CT.

C Lücke, B Oppolzer, P Werner, B Foldyna, P Lurz, T Jochimsen, B Brenneis, L Lehmkuhl, B Sattler, M Grothoff and 3 more

Open access · hybridAbstract readComparative Study
In one paragraph

Article in European radiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. Article
  3. Simultaneous assessment of left ventricular mechanical dyssynchrony using integratedJournal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2023
    Article
  4. Article
  5. Impact of ECG gating methods on the assessment of left ventricular cardiac function using PET/MRI.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2023
    Article
  6. Value of PET ECG gating in a cross-validation study of cardiac function assessment by PET/MR imaging.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2023
    Article
  7. Evaluation of left ventricular volumes and ejection fraction byJournal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2021
    Article
  8. Article
  9. Emerging Tracers for Nuclear Cardiac PET Imaging.Nuclear medicine and molecular imaging · 2018
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 2 countries.

C LückeDepartment of Diagnostic and Interventional Radiology, University Leipzig - Heart Center, Strümpellstr. 39, 04289, Leipzig, Germany. cluecke@gmx.de.
B OppolzerDepartment of Nuclear Medicine, University Hospital Leipzig, Leipzig, Germany.
P WernerDepartment of Nuclear Medicine, University Hospital Leipzig, Leipzig, Germany.
B FoldynaDepartment of Diagnostic and Interventional Radiology, University Leipzig - Heart Center, Strümpellstr. 39, 04289, Leipzig, Germany.
P LurzClinic for Internal Medicine/Cardiology, University Leipzig - Heart Center, Leipzig, Germany.
T JochimsenDepartment of Nuclear Medicine, University Hospital Leipzig, Leipzig, Germany.
B BrenneisDepartment of Diagnostic and Interventional Radiology, University Leipzig - Heart Center, Strümpellstr. 39, 04289, Leipzig, Germany.
L LehmkuhlRadiologische Klinik, Herz- und Gefäß-Klinik GmbH, Bad Neustadt, Germany.
B SattlerDepartment of Nuclear Medicine, University Hospital Leipzig, Leipzig, Germany.
M GrothoffDepartment of Diagnostic and Interventional Radiology, University Leipzig - Heart Center, Strümpellstr. 39, 04289, Leipzig, Germany.
H BarthelDepartment of Nuclear Medicine, University Hospital Leipzig, Leipzig, Germany.
O SabriDepartment of Nuclear Medicine, University Hospital Leipzig, Leipzig, Germany.
M GutberletDepartment of Diagnostic and Interventional Radiology, University Leipzig - Heart Center, Strümpellstr. 39, 04289, Leipzig, Germany.
Leipzig Heart Institute · DEUniversity Hospital Leipzig · DERhön-Klinikum · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo compare cardiac left ventricular (LV) parameters in simultaneously acquired hybrid fluorine-18-fluorodeoxyglucose ([18F] FDG) positron emission tomography/magnetic resonance imaging (PET/MRI) in patients with residual tracer activity of upstream PET/CT.

methodsTwenty-nine patients (23 men, age 58±17 years) underwent cardiac PET/MRI either directly after a non-cardiac PET/CT with homogenous cardiac [18F] FDG uptake (n=20) or for viability assessment (n=9). Gated cardiac [18F] FDG PET and cine MR sequences were acquired simultaneously and evaluated blinded to the cross-imaging results. Image quality (IQ), end-diastolic (LVEDV), end-systolic volume (LVESV), ejection fraction (LVEF) and myocardial mass (LVMM) were measured. Pearson correlation and intraclass correlation coefficient (ICC), regression and a Bland-Altman analysis were assessed.

resultsExcept LVMM, volumetric and functional LV parameters demonstrated high correlations (LVESV: r=0.97, LVEDV: r=0.95, LVEF: r=0.91, LVMM: r=0.87, each p<0.05), but wide limits of agreement (LOA) for LVEDV (-25.3-82.5ml); LVESV (-33.1-72.7ml); LVEF (-18.9-14.8%) and LVMM (-78.2-43.2g). Intra- and interobserver reliability were very high (ICC≥0.95) for all parameters, except for MR-LVEF (ICC=0.87). PET-IQ (0-3) was high (mean: 2.2±0.9) with significant influence on LVMM calculations only.

conclusionIn simultaneously acquired cardiac PET/MRI data, LVEDV, LVESV and LVEF show good agreement. However, the agreement seems to be limited if cardiac PET/MRI follows PET/CT and only the residual activity is used. KEY POINTS: • [

Indexed as

Positron Emission Tomography Computed TomographyStroke VolumeAdultAgedCoronary Artery DiseaseFemaleFluorodeoxyglucose F18Heart VentriclesHumansMagnetic Resonance ImagingMaleMiddle AgedPositron-Emission TomographyReproducibility of ResultsVentricular Function, LeftFluorodeoxyglucose F18Cardiac function testCardiac-gated imaging techniquesCardiac volumeMagnetic resonance imaging/methods*Positron emission tomography/methods*

Identifiers

PMID28631080
PMCPMC5674117
OpenAlexW2698221404

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.