Evidence map›Paper›PMID 28630952›Full record

Article... IEEE-EMBS International Conference on Biomedical and Health Informatics. IEEE-EMBS International Conference on Biomedical and Health Informatics2017

Estimating Patient's Health State Using Latent Structure Inferred from Clinical Time Series and Text.

Aaron Zalewski, William Long, Alistair E W Johnson, Roger G Mark, Li-Wei H Lehman

Abstract read
In one paragraph

Article in ... IEEE-EMBS International Conference on Biomedical and Health Informatics. IEEE-EMBS International Conference on Biomedical and Health Informatics, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Assessing the Readability of Freely Available ICU Notes.AMIA Joint Summits on Translational Science proceedings. AMIA Joint Summits on Translational Science · 2019
    Article
  3. Article
  4. Phenotyping Hypotensive Patients in Critical Care Using Hospital Discharge Summaries.... IEEE-EMBS International Conference on Biomedical and Health Informatics. IEEE-EMBS International Conference on Biomedical and Health Informatics · 2017
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Aaron ZalewskiInstitute for Medical Engineering and Science, Massachusetts Institute of Technology, Cambridge, MA.
William LongInstitute for Medical Engineering and Science, Massachusetts Institute of Technology, Cambridge, MA.
Alistair E W JohnsonInstitute for Medical Engineering and Science, Massachusetts Institute of Technology, Cambridge, MA.
Roger G MarkInstitute for Medical Engineering and Science, Massachusetts Institute of Technology, Cambridge, MA.
Li-Wei H LehmanInstitute for Medical Engineering and Science, Massachusetts Institute of Technology, Cambridge, MA.

Funding

Integrating Data, Models, and Reasoning in Critical CareR01EB001659 · NIBIB · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI MARK, ROGER GREENWOOD · 2003 to 2012
$9.8M
Research Resource for Complex Physiologic SignalsR01GM104987 · NIGMS · BETH ISRAEL DEACONESS MEDICAL CENTER · PI GOLDBERGER, ARY LOUIS, MARK, ROGER GREENWOOD · 2012 to 2019
$5.8M
Critical Care Informatics: Ethical considerations around the use and sharing of health-related dataR01EB017205 · NIBIB · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI CELI, LEO ANTHONY G, MARK, ROGER GREENWOOD · 2014 to 2021
$3.8M
NIBIB NIH HHS R01 EB001659NIBIB NIH HHS R01 EB017205NIGMS NIH HHS R01 GM104987
6 · The paper itself

Abstract

Modern intensive care units (ICUs) collect large volumes of data in monitoring critically ill patients. Clinicians in the ICUs face the challenge of interpreting large volumes of high-dimensional data to diagnose and treat patients. In this work, we explore the use of Hierarchical Dirichlet Processes (HDP) as a Bayesian nonparametric framework to infer patients' states of health by combining multiple sources of data. In particular, we employ HDP to combine clinical time series and text from the nursing progress notes in a probabilistic topic modeling framework for patient risk stratification. Given a patient cohort, we use HDP to infer latent "topics" shared across multimodal patient data from the entire cohort. Each topic is modeled as a multinomial distribution over a vocabulary of codewords, defined over heterogeneous data sources. We evaluate the clinical utility of the learned topic structure using the first 24-hour ICU data from over 17,000 adult patients in the MIMIC-II database to estimate patients' risks of in-hospital mortality. Our results demonstrate that our approach provides a viable framework for combining different data modalities to model patient's states of health, and can potentially be used to generate alerts to identify patients at high risk of hospital mortality.

Identifiers

PMID28630952
PMCPMC5473944

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.