Evidence map›Paper›PMID 28630633›Full record

ArticleEvidence-based complementary and alternative medicine : eCAM2017

DJC Suppresses Advanced Glycation End Products-Induced JAK-STAT Signaling and ROS in Mesangial Cells.

Min Sun, Yan Li, Wenjie Bu, Jindong Zhao, Jianliang Zhu, Lingling Gu, Pingping Zhang, Zhaohui Fang

Open access · hybridAbstract read
In one paragraph

Article in Evidence-based complementary and alternative medicine : eCAM, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.9field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 18 citations in OpenAlex.

  1. Inflammation in glomerular diseases.Frontiers in immunology · 2025
    Review
  2. Review
  3. Article
  4. JAK/STAT signaling in diabetic kidney disease.Frontiers in cell and developmental biology · 2023
    Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Min SunAnhui Province Key Laboratory of R&D of Chinese Medicine, School of Life Science, Anhui University, Hefei, Anhui 230601, China.
Yan LiAnhui Province Key Laboratory of R&D of Chinese Medicine, School of Life Science, Anhui University, Hefei, Anhui 230601, China.
Wenjie BuAnhui Province Key Laboratory of R&D of Chinese Medicine, School of Life Science, Anhui University, Hefei, Anhui 230601, China.
Jindong ZhaoDepartment of Endocrinology, The First Affiliated Hospital of Anhui University of TCM, Hefei, Anhui 230031, China.
Jianliang ZhuAnhui Province Key Laboratory of R&D of Chinese Medicine, School of Life Science, Anhui University, Hefei, Anhui 230601, China.
Lingling GuAnhui Province Key Laboratory of R&D of Chinese Medicine, School of Life Science, Anhui University, Hefei, Anhui 230601, China.
Pingping ZhangAnhui Province Key Laboratory of R&D of Chinese Medicine, School of Life Science, Anhui University, Hefei, Anhui 230601, China.
Zhaohui FangDepartment of Endocrinology, The First Affiliated Hospital of Anhui University of TCM, Hefei, Anhui 230031, China.ORCID 0000-0003-0258-7696
Anhui University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The antidiabetic properties and anti-inflammatory effects of Danzhi Jiangtang Capsules (DJC) have been demonstrated in clinical and laboratory experiments. In this study, we explored whether DJC can ameliorate advanced glycation end products- (AGEs-) mediated cell injury and the precise mechanisms of DJC in treating diabetic nephropathy (DN). Western blot analysis was employed to assess the expressions of iNOS, COX2, and SOCS and the phosphorylation of JAK2, STAT1, and STAT3 in glomerular mesangial cells (GMCs) after treatment with DJC. TNF-

Identifiers

PMID28630633
PMCPMC5467335
OpenAlexW2617929023

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.