Evidence map›Paper›PMID 28630333›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2017

Boosting CNS axon regeneration by harnessing antagonistic effects of GSK3 activity.

Marco Leibinger, Anastasia Andreadaki, Renate Golla, Evgeny Levin, Alexander M Hilla, Heike Diekmann, Dietmar Fischer

Open access · bronzeAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers.

0numbers the graph read from it
0cells of the map it votes in
45citing papers in PubMed
4.3field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

45 citing papers in PubMed, 73 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Marco LeibingerDivision of Experimental Neurology, Department of Neurology, Heinrich Heine University of Düsseldorf, 40225 Duesseldorf, Germany.
Anastasia AndreadakiDivision of Experimental Neurology, Department of Neurology, Heinrich Heine University of Düsseldorf, 40225 Duesseldorf, Germany.
Renate GollaDivision of Experimental Neurology, Department of Neurology, Heinrich Heine University of Düsseldorf, 40225 Duesseldorf, Germany.
Evgeny LevinDivision of Experimental Neurology, Department of Neurology, Heinrich Heine University of Düsseldorf, 40225 Duesseldorf, Germany.
Alexander M HillaDivision of Experimental Neurology, Department of Neurology, Heinrich Heine University of Düsseldorf, 40225 Duesseldorf, Germany.
Heike DiekmannDivision of Experimental Neurology, Department of Neurology, Heinrich Heine University of Düsseldorf, 40225 Duesseldorf, Germany.
Dietmar FischerDivision of Experimental Neurology, Department of Neurology, Heinrich Heine University of Düsseldorf, 40225 Duesseldorf, Germany dietmar.fischer@uni-duesseldorf.de.
Heinrich Heine University Düsseldorf · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Implications of GSK3 activity for axon regeneration are often inconsistent, if not controversial. Sustained GSK3 activity in GSK3

Indexed as

RegenerationAnimalsAxonsCentral Nervous SystemFemaleGlycogen Synthase Kinase 3Intercellular Signaling Peptides and ProteinsMaleMiceMice, Inbred C57BLMice, KnockoutMice, TransgenicMicrotubule-Associated ProteinsMyelin SheathNerve RegenerationNerve Tissue Proteinscollapsin response mediator protein-2Glycogen Synthase Kinase 3Intercellular Signaling Peptides and Proteinsmicrotubule-associated protein 1BMicrotubule-Associated ProteinsNerve Tissue Proteinsaxon regenerationCNSCRMP2GSK3MAP1B

Identifiers

PMID28630333
PMCPMC5502600
OpenAlexW2671029578

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.