ArticleProceedings of the National Academy of Sciences of the United States of America2017
Virus-induced inflammasome activation is suppressed by prostaglandin D
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Article in Proceedings of the National Academy of Sciences of the United States of America, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers.
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45citing papers in PubMed
2.5field-weighted citation impact, top 10% of its field
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Who cites it
45 citing papers in PubMed, 65 citations in OpenAlex.
- Targeting the HPGDS-PGDSignal transduction and targeted therapy · 2026Article
- Prostaglandins: Key players in immunomodulation of the nervous system.Neural regeneration research · 2026Article
- Assessment of lipid mediators in the urine of patients with Lyme disease, tick-borne encephalitis and human granulocytic anaplasmosis.Scientific reports · 2026Article
- Prostaglandin D2 axis impairs immunity against melanoma via dendritic cells and γδ T cells in middle-aged mice.Journal of immunology (Baltimore, Md. : 1950) · 2026Article
- Heterologous expression of HCoV-HKU1 ORF 7b by mouse hepatitis virus protects against severe disease during murine infection.PLoS pathogens · 2025Article
- Article
- Molecular basis for ligand recognition and receptor activation of the prostaglandin D2 receptor DP1.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Sphingosine kinase 2 suppresses neutrophil responses to promote viral persistence while attenuating immune pathology.Frontiers in immunology · 2025Article
- Dual therapy with corticosteroid ablates the beneficial effect of DP2 antagonism in chronic experimental asthma.Nature communications · 2024Article
- Erdr1 Drives Macrophage Programming via Dynamic Interplay with YAP1 and Mid1.ImmunoHorizons · 2024Article
- Erdr1 orchestrates macrophage polarization and determines cell fate via dynamic interplay with YAP1 and Mid1.bioRxiv : the preprint server for biology · 2023Article
- Polyunsaturated Fatty Acid-Derived Lipid Mediators as Potential Biomarkers for Leprosy Among Individuals with AsymptomaticACS infectious diseases · 2023Article
- Possible Pathogenesis and Prevention of Long COVID: SARS-CoV-2-Induced Mitochondrial Disorder.International journal of molecular sciences · 2023Review
- Serum lipid mediator profiles in COVID-19 patients and lung disease severity: a pilot study.Scientific reports · 2023Article
- AIM2 sensors mediate immunity toProceedings of the National Academy of Sciences of the United States of America · 2023Article
- Role of epigenetics and the transcription factor Sp1 in the expression of the D prostanoid receptor 1 in human cartilage.Frontiers in cell and developmental biology · 2023Article
- Anti-inflammatory effects of the prostaglandin DVeterinary research · 2022Article
- Contribution of Lipid Mediators in Divergent Outcomes following Acute Bacterial and Viral Lung Infections in the Obese Host.Journal of immunology (Baltimore, Md. : 1950) · 2022Article
- Article
- Direct type I interferon signaling in hepatocytes controls malaria.Cell reports · 2022Article
Corrections and comments
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Authors and funding
12 authors at 2 institutions in 2 countries.
Rahul VijayInterdisciplinary Program in Immunology, University of Iowa, Iowa City, IA 52242.
Anthony R FehrDepartment of Microbiology, University of Iowa, Iowa City, IA 52242.
Ann M JanowskiInterdisciplinary Program in Immunology, University of Iowa, Iowa City, IA 52242.
Jeremiah AthmerDepartment of Microbiology, University of Iowa, Iowa City, IA 52242.
Dorthea L WheelerInterdisciplinary Program in Immunology, University of Iowa, Iowa City, IA 52242.
Matthew GrunewaldDepartment of Microbiology, University of Iowa, Iowa City, IA 52242.
Ramakrishna SompallaeIowa Institute of Human Genetics, University of Iowa, Iowa City, IA 52242.
Samarchith P KurupDepartment of Microbiology, University of Iowa, Iowa City, IA 52242.
David K MeyerholzDepartment of Pathology, University of Iowa, Iowa City, IA 52242.
Fayyaz S SutterwalaInterdisciplinary Program in Immunology, University of Iowa, Iowa City, IA 52242.
Shuh NarumiyaDepartment of Pharmacology, Kyoto University Faculty of Medicine, Tokyo, Japan 606-8501.
Stanley PerlmanInterdisciplinary Program in Immunology, University of Iowa, Iowa City, IA 52242; stanley-perlman@uiowa.edu.ORCID 0000-0003-4213-2354
University of Iowa · USKyoto University · JP
Funding
Viral VectorP30CA086862 · NCI · UNIVERSITY OF IOWA · PI Douglas Robert Spitz · 2000 to 2026
$70.0MVector Core-Core 2P30DK054759 · NIDDK · UNIVERSITY OF IOWA · PI Alejandro Antonio Pezzulo · 1998 to 2026
$30.5MMEDICAL SCIENTIST TRAINING PROGRAMT32GM007337 · NIGMS · UNIVERSITY OF IOWA · PI GEYER, PAMELA K., LENTZ, STEVEN R · 1985 to 2020
$15.9MTRAINING IN MECHANISMS OF PARASITISMT32AI007511 · NIAID · UNIVERSITY OF IOWA · PI BUTLER, NOAH SULLIVAN, WEBER, MARY · 1996 to 2025
$8.1MRole of microglia in MHV-induced demyelinationR01NS036592 · NINDS · UNIVERSITY OF IOWA · PI PERLMAN, STANLEY · 1997 to 2021
$6.0MPREDOCTORAL TRAINING PROGRAM IN IMMUNOLOGYT32AI007485 · NIAID · UNIVERSITY OF IOWA · PI Kevin L Legge · 1995 to 2026
$5.4MTraining in Molecular Virology, Viral Pathogenesis and Viral VectorsT32AI007533 · NIAID · UNIVERSITY OF IOWA · PI Stanley Perlman · 1998 to 2026
$2.5MTargeting the NLRP3 inflammasome to limit pathologic sterile inflammationR01AI118719 · NIAID · CEDARS-SINAI MEDICAL CENTER · PI SUTTERWALA, FAYYAZ S. · 2016 to 2020
$2.2MNCI NIH HHS P30 CA086862NIAID NIH HHS R01 AI118719NIAID NIH HHS T32 AI007485NIAID NIH HHS T32 AI007511NIAID NIH HHS T32 AI007533NIDDK NIH HHS P30 DK054759NIGMS NIH HHS T32 GM007337NINDS NIH HHS R01 NS036592
Abstract
Prostaglandin D2 (PGD
Indexed as
CoronavirusSignal TransductionAnimalsCyclic AMPCytokinesHumansInflammasomesInflammationInterferon Type IInterleukin-1betaMacrophagesMiceMice, Inbred C57BLOligonucleotide Array Sequence AnalysisProstaglandin D2Protein DomainsCyclic AMPCytokinesIL1B protein, humanIL1B protein, mouseInflammasomesInterferon Type IInterleukin-1betaProstaglandin D2prostanoid D receptor 1, humanprostanoid D receptor 1, mouseReceptors, Prostaglandincoronavirusencephalitisinflammasomesprostaglandin D2pyrin domain-only protein
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.