Evidence map›Paper›PMID 28630311›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2017

A prokaryotic viral sequence is expressed and conserved in mammalian brain.

Yang-Hui Yeh, Vignesh Gunasekharan, Laura Manuelidis

Open access · bronzeAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.8field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 13 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Yang-Hui YehSection of Neuropathology, Yale University Medical School, New Haven, CT 06510.
Vignesh GunasekharanSection of Neuropathology, Yale University Medical School, New Haven, CT 06510.
Laura ManuelidisSection of Neuropathology, Yale University Medical School, New Haven, CT 06510 laura.manuelidis@yale.edu.
Yale University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A natural and permanent transfer of prokaryotic viral sequences to mammals has not been reported by others. Circular "SPHINX" DNAs <5 kb were previously isolated from nuclease-protected cytoplasmic particles in rodent neuronal cell lines and brain. Two of these DNAs were sequenced after Φ29 polymerase amplification, and they revealed significant but imperfect homology to segments of commensal

Indexed as

AcinetobacterAnimalsBacteriophagesBrainCell DifferentiationCytoplasmDNA, CircularEvolution, MolecularHumansMiceMicrobiotaOpen Reading FramesPrionsRabbitsSequence Analysis, DNASynapsesDNA, CircularPrionscircular viral DNAevolutionmaternal inheritancemicrobiomesynaptic boutons

Identifiers

PMID28630311
PMCPMC5502646
OpenAlexW2658736527

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.