Evidence map›Paper›PMID 28630290›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2017

Childhood social class and cognitive aging in the Swedish Adoption/Twin Study of Aging.

Malin Ericsson, Cecilia Lundholm, Stefan Fors, Anna K Dahl Aslan, Catalina Zavala, Chandra A Reynolds, Nancy L Pedersen

Abstract readTwin Study
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed.

  1. The Interplay of Genes and Environment Across Multiple Studies (IGEMS) Consortium After Fifteen Years.Twin research and human genetics : the official journal of the International Society for Twin Studies · 2026
    Article
  2. Article
  3. Article
  4. Early-Life Maternal Relationship Quality and Cognitive Function in Later Life: Mediating Role of Social Resources?The journals of gerontology. Series B, Psychological sciences and social sciences · 2025
    Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Drivers of Frailty from Adulthood into Old Age: Results from a 27-Year Longitudinal Population-Based Study in Sweden.The journals of gerontology. Series A, Biological sciences and medical sciences · 2020
    Article
  15. Early-Life Conditions and Cognitive Function in Middle-and Old-Aged Chinese Adults: A Longitudinal Study.International journal of environmental research and public health · 2020
    Article
  16. Article
  17. Article
  18. Article
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Malin EricssonDepartment of Medical Epidemiology and Biostatistics, Karolinska Institutet, 171 77 Stockholm, Sweden; malin.ericsson@ki.se.ORCID 0000-0002-0647-0148
Cecilia LundholmDepartment of Medical Epidemiology and Biostatistics, Karolinska Institutet, 171 77 Stockholm, Sweden.
Stefan ForsAging Research Center, Karolinska Institutet & Stockholm University, 171 77 Stockholm, Sweden.
Anna K Dahl AslanDepartment of Medical Epidemiology and Biostatistics, Karolinska Institutet, 171 77 Stockholm, Sweden.
Catalina ZavalaDepartment of Medical Epidemiology and Biostatistics, Karolinska Institutet, 171 77 Stockholm, Sweden.
Chandra A ReynoldsDepartment of Psychology, University of California, Riverside, CA 92521.
Nancy L PedersenDepartment of Medical Epidemiology and Biostatistics, Karolinska Institutet, 171 77 Stockholm, Sweden.

Funding

Gene-Environment Interplay of Social Contexts and Aging-Related OutcomesR01AG037985 · NIA · UNIVERSITY OF SOUTHERN CALIFORNIA · PI PEDERSEN, NANCY L · 2010 to 2014
$3.2M
Gene-Environment Interplay of Social Contexts and Aging-Related OutcomesR56AG037985 · NIA · UNIVERSITY OF SOUTHERN CALIFORNIA · PI GATZ, MARGARET, PEDERSEN, NANCY L · 2016 to 2016
$818k
NIA NIH HHS R01 AG037985NIA NIH HHS R56 AG037985
6 · The paper itself

Abstract

In this report we analyzed genetically informative data to investigate within-person change and between-person differences in late-life cognitive abilities as a function of childhood social class. We used data from nine testing occasions spanning 28 y in the Swedish Adoption/Twin Study of Aging and parental social class based on the Swedish socioeconomic index. Cognitive ability included a general factor and the four domains of verbal, fluid, memory, and perceptual speed. Latent growth curve models of the longitudinal data tested whether level and change in cognitive performance differed as a function of childhood social class. Between-within twin-pair analyses were performed on twins reared apart to assess familial confounding. Childhood social class was significantly associated with mean-level cognitive performance at age 65 y, but not with rate of cognitive change. The association decreased in magnitude but remained significant after adjustments for level of education and the degree to which the rearing family was supportive toward education. A between-pair effect of childhood social class was significant in all cognitive domains, whereas within-pair estimates were attenuated, indicating genetic confounding. Thus, childhood social class is important for cognitive performance in adulthood on a population level, but the association is largely attributable to genetic influences.

Indexed as

AdoptionCognitive AgingSocial ClassAgedAged, 80 and overCognitionFemaleHumansIndividualityLongitudinal StudiesMaleMiddle AgedNeuropsychological TestsPhenotypeSocial EnvironmentSwedenadoptionchildhood social classcognitive agingtwins

Identifiers

PMID28630290
PMCPMC5502597

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.