Trial reportCirculation2017
Early Myocardial Strain Changes During Potentially Cardiotoxic Chemotherapy May Occur as a Result of Reductions in Left Ventricular End-Diastolic Volume: The Need to Interpret Left Ventricular Strain With Volumes.
Abstract readClinical TrialLetter
In one paragraph
Trial report in Circulation, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.
0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
39 citing papers in PubMed.
- Statins Do Not Significantly Affect Oxidative Nitrosative Stress Biomarkers in the PREVENT Randomized Clinical Trial.Clinical cancer research : an official journal of the American Association for Cancer Research · 2024Trial
- Long-Term Fatigue After Treatment for Breast Cancer.JAMA network open · 2026Article
- How to Use Multimodality Imaging in Cardio-Oncology.Journal of cardiovascular development and disease · 2026Review
- Prospective multicenter evaluation of 18F-FDG PET/CT and strain for early cardiotoxicity detection in lymphoma patients.Cardio-oncology (London, England) · 2025Article
- Cardiac magnetic resonance imaging in the assessment of cardiac injury and toxicity from cancer-related chemotherapy.Pediatric radiology · 2025Review
- Matters of the Heart: Cardiotoxicity Related to Target Therapy in Oncogene-Addicted Non-Small Cell Lung Cancer.International journal of molecular sciences · 2025Review
- Interdisciplinary Management of Cardiotoxicity in Outpatient Settings: A Survey on Practices, Perceptions and Potential for Improvement.European cardiology · 2025Article
- Assessment of myocardial deformation by CMR tissue tracking reveals left ventricular subclinical myocardial dysfunction in patients with gynecologic cancer undergoing chemotherapy.Frontiers in oncology · 2025Article
- Utilities and Limitations of Cardiac Magnetic Resonance Imaging in Dilated Cardiomyopathy.Korean journal of radiology · 2023Review
- Straining for More Evidence.JACC. CardioOncology · 2023Article
- Physical Activity During Breast Cancer Therapy Associates With Preserved Exercise Capacity and Cardiac Function (WF97415).JACC. CardioOncology · 2023Article
- Multimodality imaging in cardio-oncology: the added value of CMR and CCTA.The British journal of radiology · 2023Review
- Sex-Specific Evaluation of Arterial Stiffness and Left Ventricular Remodeling: Can We Rely on Dimensionless Ratios?JACC. Advances · 2023Article
- Global Longitudinal Strain in Cardio-Oncology: A Review.Cancers · 2023Review
- Diagnosis and Management of Cancer Treatment-Related Cardiac Dysfunction and Heart Failure in Children.Children (Basel, Switzerland) · 2023Review
- Heart Failure and Cardiomyopathies: CT and MR from Basics to Advanced Imaging.Diagnostics (Basel, Switzerland) · 2022Review
- Statins and Left Ventricular Ejection Fraction Following Doxorubicin Treatment.NEJM evidence · 2022Article
- Cardiotoxicity monitoring of pyrotinib in combination with nab-paclitaxel, doxorubicin, and cyclophosphamide in HER2-positive breast cancer: a single-armed clinical trial.Gland surgery · 2022Article
- Multimodality Advanced Cardiovascular and Molecular Imaging for Early Detection and Monitoring of Cancer Therapy-Associated Cardiotoxicity and the Role of Artificial Intelligence and Big Data.Frontiers in cardiovascular medicine · 2022Review
- Cardiac MRI assessment of anthracycline-induced cardiotoxicity.Frontiers in cardiovascular medicine · 2022Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Jennifer H JordanFrom Department of Internal Medicine, Section on Cardiovascular Medicine (J.H.J., B.S., G.C.M., W.G.H.), Department of Pathology, Section on Comparative Medicine (G.C.M.), Division of Public Health Sciences, Section on Biostatistical Sciences (R.B.D.), and Department of Radiological Sciences (W.G.H.), Wake Forest School of Medicine, Winston-Salem, NC; and Medical Imaging Technologies, Siemens Healthcare, Princeton, NJ (M.P.-J.).
Bunyapon SukpraphruteFrom Department of Internal Medicine, Section on Cardiovascular Medicine (J.H.J., B.S., G.C.M., W.G.H.), Department of Pathology, Section on Comparative Medicine (G.C.M.), Division of Public Health Sciences, Section on Biostatistical Sciences (R.B.D.), and Department of Radiological Sciences (W.G.H.), Wake Forest School of Medicine, Winston-Salem, NC; and Medical Imaging Technologies, Siemens Healthcare, Princeton, NJ (M.P.-J.).
Giselle C MeléndezFrom Department of Internal Medicine, Section on Cardiovascular Medicine (J.H.J., B.S., G.C.M., W.G.H.), Department of Pathology, Section on Comparative Medicine (G.C.M.), Division of Public Health Sciences, Section on Biostatistical Sciences (R.B.D.), and Department of Radiological Sciences (W.G.H.), Wake Forest School of Medicine, Winston-Salem, NC; and Medical Imaging Technologies, Siemens Healthcare, Princeton, NJ (M.P.-J.).
Marie-Pierre JollyFrom Department of Internal Medicine, Section on Cardiovascular Medicine (J.H.J., B.S., G.C.M., W.G.H.), Department of Pathology, Section on Comparative Medicine (G.C.M.), Division of Public Health Sciences, Section on Biostatistical Sciences (R.B.D.), and Department of Radiological Sciences (W.G.H.), Wake Forest School of Medicine, Winston-Salem, NC; and Medical Imaging Technologies, Siemens Healthcare, Princeton, NJ (M.P.-J.).
Ralph B D'AgostinoFrom Department of Internal Medicine, Section on Cardiovascular Medicine (J.H.J., B.S., G.C.M., W.G.H.), Department of Pathology, Section on Comparative Medicine (G.C.M.), Division of Public Health Sciences, Section on Biostatistical Sciences (R.B.D.), and Department of Radiological Sciences (W.G.H.), Wake Forest School of Medicine, Winston-Salem, NC; and Medical Imaging Technologies, Siemens Healthcare, Princeton, NJ (M.P.-J.).
W Gregory HundleyFrom Department of Internal Medicine, Section on Cardiovascular Medicine (J.H.J., B.S., G.C.M., W.G.H.), Department of Pathology, Section on Comparative Medicine (G.C.M.), Division of Public Health Sciences, Section on Biostatistical Sciences (R.B.D.), and Department of Radiological Sciences (W.G.H.), Wake Forest School of Medicine, Winston-Salem, NC; and Medical Imaging Technologies, Siemens Healthcare, Princeton, NJ (M.P.-J.). ghundley@wakehealth.edu.
Funding
Tumor Tissue CoreP30CA012197 · NCI · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI Ruben A. Mesa · 1985 to 2026
$55.4MPreventing Anthracycline Cardiovascular Toxicity with StatinsR01HL118740 · NHLBI · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI HUNDLEY, WILLIAM GREGORY · 2013 to 2018
$4.2MUnderstanding and Predicting Fatigue, CV Decline & Events After Breast CA TreatmentR01CA199167 · NCI · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI HUNDLEY, WILLIAM GREGORY · 2015 to 2022
$3.2MEarly Imaging Detection of CV Injury after CancerR01CA167821 · NCI · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI HUNDLEY, WILLIAM GREGORY, JOLLY, MARIE-PIERRE · 2012 to 2016
$2.5MOptimized CMR imaging of chemotherapy cardiotoxicityR33CA121296 · NCI · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI HUNDLEY, WILLIAM GREGORY · 2007 to 2009
$716kNCI NIH HHS P30 CA012197NCI NIH HHS R01 CA167821NCI NIH HHS R01 CA199167NCI NIH HHS R33 CA121296NHLBI NIH HHS R01 HL118740
Abstract
PubMed holds no abstract for this paper.
Indexed as
CardiotoxinsMagnetic Resonance ImagingMyocardiumNeoplasmsAdultAgedHumansMaleMiddle AgedStroke VolumeVentricular Function, LeftCardiotoxinscardiotoxicitymagnetic resonance imagingventricular dysfunction, left
Identifiers
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.