Evidence map›Paper›PMID 28630231›Full record

ReviewJournal of the American Society of Nephrology : JASN2017

Understanding Medication Nonadherence after Kidney Transplant.

Thomas E Nevins, Peter W Nickerson, Mary Amanda Dew

Abstract readReview
In one paragraph

Review in Journal of the American Society of Nephrology : JASN, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 55 papers.

0numbers the graph read from it
0cells of the map it votes in
55citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

55 citing papers in PubMed.

  1. Trial
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  4. Review
  5. Article
  6. Review
  7. Health psychology and behavioral medicine · 2026
    Article
  8. Article
  9. Population Health Management for Improving Kidney Health Outcomes.American journal of kidney diseases : the official journal of the National Kidney Foundation · 2025
    Article
  10. Review
  11. Article
  12. Article
  13. Frontiers in immunology · 2025
    Article
  14. Review
  15. Review
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Thomas E NevinsDepartment of Pediatrics, University of Minnesota, Minneapolis, Minnesota.
Peter W NickersonDepartment of Medicine, University of Manitoba, Winnipeg, Manitoba, Canada; and.
Mary Amanda DewDepartment of Psychiatry, University of Pittsburgh School of Medicine and Medical Center, Pittsburgh, Pennsylvania dewma@upmc.edu.

Funding

Epitope mismatch and medication nonadherenceR34AI118416 · NIAID · UNIVERSITY OF MINNESOTA · PI MATAS, ARTHUR J · 2016 to 2016
$245k
NIAID NIH HHS R34 AI118416
6 · The paper itself

Abstract

Alloimmunity remains a barrier to long-term graft survival that necessitates lifelong immunosuppressive therapy after renal transplant. Medication nonadherence has been increasingly recognized as a major impediment to achieving effective immunosuppression. Electronic medication monitoring further reveals that nonadherence manifests early after transplant, although the effect is delayed. The etiology of nonadherence is multifactorial, with the strongest risk factors including past nonadherence and being an adolescent or young adult. Other risk factors with smaller but consistently important effects include minority race/ethnicity, poor social supports, and poor perceived health. In children, risk factors related to parental and child psychologic and behavioral functioning and parental distress and burden are also important. Qualitative systematic reviews highlight the need to tailor interventions to each transplant recipient's unique needs, motivations, and barriers rather than offer a one size fits all approach. To date, relatively few interventions have been studied, and most studies conducted were underpowered to allow definitive conclusions. If the kidney transplant community's goal of "one transplant for life" is to become a reality, then solutions for medication nonadherence must be found and implemented.

Indexed as

Drug MonitoringKidney TransplantationMedication AdherenceHumansImmunosuppressive AgentsRisk FactorsImmunosuppressive Agentsrejectionrenal transplantationtransplant outcomes

Identifiers

PMID28630231
PMCPMC5533244

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.