Evidence map›Paper›PMID 28630204›Full record

ArticleAntimicrobial agents and chemotherapy2017

A Low-Molecular-Weight Alginate Oligosaccharide Disrupts Pseudomonal Microcolony Formation and Enhances Antibiotic Effectiveness.

Manon F Pritchard, Lydia C Powell, Alison A Jack, Kate Powell, Konrad Beck, Hannah Florance, Julian Forton, Philip D Rye, Arne Dessen, Katja E Hill and 1 more

Open access · bronzeAbstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed
9.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 88 citations in OpenAlex.

  1. Role of cell-associated and secretion-independent virulence factors of Pseudomonas aeruginosa in microbial keratitis and anti-virulence therapeutic strategies.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2026
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  6. Degradation of NaturalMarine drugs · 2024
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  11. How Three Self-Secreted Biofilm Exopolysaccharides ofInternational journal of molecular sciences · 2023
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  18. Enhancing Colistin Activity against Colistin-ResistantPharmaceuticals (Basel, Switzerland) · 2022
    Article
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  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 2 countries.

Manon F PritchardAdvanced Therapies Group, Cardiff University School of Dentistry, Cardiff, United Kingdom pritchardmf@cardiff.ac.uk.
Lydia C PowellAdvanced Therapies Group, Cardiff University School of Dentistry, Cardiff, United Kingdom.
Alison A JackAdvanced Therapies Group, Cardiff University School of Dentistry, Cardiff, United Kingdom.
Kate PowellAdvanced Therapies Group, Cardiff University School of Dentistry, Cardiff, United Kingdom.
Konrad BeckAdvanced Therapies Group, Cardiff University School of Dentistry, Cardiff, United Kingdom.
Hannah FloranceDepartment of Biosciences, College of Life and Environmental Sciences, Exeter University, Exeter, United Kingdom.
Julian FortonChildrens Hospital of Wales, Paediatric Respiratory Medicine, Cardiff, United Kingdom.
Philip D RyeAlgiPharma AS, Sandvika, Norway.
Arne DessenAlgiPharma AS, Sandvika, Norway.
Katja E HillAdvanced Therapies Group, Cardiff University School of Dentistry, Cardiff, United Kingdom.
David W ThomasAdvanced Therapies Group, Cardiff University School of Dentistry, Cardiff, United Kingdom.
Cardiff University · GBAlgiPharma (Norway) · NONoah's Ark Children's Hospital for Wales · GBUniversity of Exeter · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In chronic respiratory disease, the formation of dense, 3-dimensional "microcolonies" by

Indexed as

AlginatesAnti-Bacterial AgentsBiofilmsColistinCystic FibrosisDrug Resistance, Multiple, BacterialDrug SynergismGlucuronic AcidHexuronic AcidsHumansMicrobial Sensitivity TestsOligosaccharidesPseudomonas aeruginosaPseudomonas InfectionsQuorum SensingRespiratory Tract InfectionsAlginatesAnti-Bacterial AgentsColistinGlucuronic AcidHexuronic AcidsOligosaccharidesalginatecolistincystic fibrosisOligoG CF-5/20Pseudomonas aeruginosa

Identifiers

PMID28630204
PMCPMC5571347
OpenAlexW2677486574

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.