Evidence map›Paper›PMID 28630189›Full record

Trial reportAntimicrobial agents and chemotherapy2017

S McCurdy, L Lawrence, M Quintas, L Woosley, R Flamm, C Tseng, S Cammarata

Abstract readClinical Trial, Phase IIIMulticenter StudyRandomized Controlled Trial
In one paragraph

Trial report in Antimicrobial agents and chemotherapy, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
47citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

47 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Analysis of Pooled Phase III Efficacy Data for Delafloxacin in Acute Bacterial Skin and Skin Structure Infections.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2019
    Trial
  5. Trial
  6. Trial
  7. Evaluation of in vitro activity of delafloxacin against Staphylococcus aureus MSSA and MRSA isolated from a Brazilian tertiary hospital.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2026
    Article
  8. Delafloxacin: what does a new fluoroquinolone offer?Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia · 2026
    Review
  9. Article
  10. Microbiology spectrum · 2026
    Article
  11. Review
  12. Review
  13. Article
  14. Article
  15. Role ofAntibiotics (Basel, Switzerland) · 2024
    Article
  16. Review
  17. Review
  18. Review
  19. TheJAC-antimicrobial resistance · 2023
    Article
  20. Clinical Impact ofAntibiotics (Basel, Switzerland) · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

S McCurdyMelinta Therapeutics, New Haven, Connecticut, USA smccurdy@melinta.com.
L LawrenceMelinta Therapeutics, New Haven, Connecticut, USA.
M QuintasMelinta Therapeutics, New Haven, Connecticut, USA.
L WoosleyJMI Laboratories, North Liberty, Iowa, USA.
R FlammJMI Laboratories, North Liberty, Iowa, USA.
C TsengH20 Clinical, Hunt Valley, Maryland, USA.
S CammarataMelinta Therapeutics, New Haven, Connecticut, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Delafloxacin is an investigational anionic fluoroquinolone antibiotic with broad-spectrum

Indexed as

Anti-Bacterial AgentsAsiaDouble-Blind MethodEuropeFluoroquinolonesHumansLevofloxacinMethicillin ResistanceMicrobial Sensitivity TestsSkinSouth AmericaStaphylococcal Skin InfectionsStaphylococcus aureusAnti-Bacterial AgentsdelafloxacinFluoroquinolonesLevofloxacinABSSSIdelafloxacinfluoroquinoloneStaphylococcus aureussusceptibility

Identifiers

PMID28630189
PMCPMC5571289

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.