ArticleAntimicrobial agents and chemotherapy2017
Loss of C-5 Sterol Desaturase Activity Results in Increased Resistance to Azole and Echinocandin Antifungals in a Clinical Isolate of Candida parapsilosis.
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Article in Antimicrobial agents and chemotherapy, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.
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0cells of the map it votes in
39citing papers in PubMed
2.6field-weighted citation impact, top 10% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
39 citing papers in PubMed, 57 citations in OpenAlex.
- Micafungin exposure drives multidrug resistance inbioRxiv : the preprint server for biology · 2026Article
- Azole Resistance in Candida parapsilosis From Patients With Burns in Mexico: A Genomic and Phylogenetic Analysis.Mycoses · 2026Article
- A Novel Erg3 T208Is Substitution Associated with Reduced Fluconazole and Voriconazole Susceptibility in ClinicalInfection and drug resistance · 2026Article
- Emerging antifungal resistance in Candida parapsilosis: the end of the innocence.npj antimicrobials and resistance · 2025Review
- Acquired amphotericin B resistance attributed to a mutatedAntimicrobial agents and chemotherapy · 2025Article
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- Acquired Amphotericin B Resistance Attributed to a MutatedbioRxiv : the preprint server for biology · 2025Article
- Threats from theMicrobiology and molecular biology reviews : MMBR · 2024Review
- A Comprehensive Analysis of the Lipidomic Signatures inJournal of fungi (Basel, Switzerland) · 2024Article
- Evolutionary dynamics in gut-colonizing Candida glabrata during caspofungin therapy: Emergence of clinically important mutations in sphingolipid biosynthesis.PLoS pathogens · 2024Article
- Article
- Erg251 has complex and pleiotropic effects on sterol composition, azole susceptibility, filamentation, and stress response phenotypes.PLoS pathogens · 2024Article
- Precise genome editing underlines the distinct contributions of mutations inAntimicrobial agents and chemotherapy · 2024Article
- Decreased echinocandin susceptibility inEmerging microbes & infections · 2023Article
- Rapid Evolution of Multidrug Resistance in a Candida lusitaniae Infection during Micafungin Monotherapy.Antimicrobial agents and chemotherapy · 2023Article
- Review
- Whole-genome sequencing confirms a persistent candidaemia clonal outbreak due to multidrug-resistant Candida parapsilosis.The Journal of antimicrobial chemotherapy · 2023Article
- Clinical Features and Outcomes of Persistent Candidemia Caused byMicroorganisms · 2023Article
- Caspofungin resistance in Candida albicans: genetic factors and synergistic compounds for combination therapies.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2022Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
17 authors at 4 institutions in 2 countries.
Jeffrey M RybakDepartment of Clinical Pharmacy, College of Pharmacy, University of Tennessee Health Science Center, Memphis, Tennessee, USA.
C Michael DickensW. Harry Feinstone Center for Genomic Research, University of Memphis, Memphis, Tennessee, USA.
Josie E ParkerInstitute of Life Science, Swansea University Medical School, Swansea, Wales, United Kingdom.
Kelly E CaudleDepartment of Clinical Pharmacy, College of Pharmacy, University of Tennessee Health Science Center, Memphis, Tennessee, USA.
Kayihura ManigabaDepartment of Clinical Pharmacy, College of Pharmacy, University of Tennessee Health Science Center, Memphis, Tennessee, USA.
Sarah G WhaleyDepartment of Clinical Pharmacy, College of Pharmacy, University of Tennessee Health Science Center, Memphis, Tennessee, USA.
Andrew T NishimotoDepartment of Clinical Pharmacy, College of Pharmacy, University of Tennessee Health Science Center, Memphis, Tennessee, USA.
Arturo Luna-TapiaDepartment of Clinical Pharmacy, College of Pharmacy, University of Tennessee Health Science Center, Memphis, Tennessee, USA.
Sujoy RoyFungus Testing Laboratory, University of Texas Health Science Center at San Antonio, San Antonio, Texas, USA.
Qing ZhangDepartment of Clinical Pharmacy, College of Pharmacy, University of Tennessee Health Science Center, Memphis, Tennessee, USA.
Katherine S BarkerDepartment of Clinical Pharmacy, College of Pharmacy, University of Tennessee Health Science Center, Memphis, Tennessee, USA.
Glen E PalmerDepartment of Clinical Pharmacy, College of Pharmacy, University of Tennessee Health Science Center, Memphis, Tennessee, USA.
Thomas R SutterW. Harry Feinstone Center for Genomic Research, University of Memphis, Memphis, Tennessee, USA.
Ramin HomayouniBioinformatics Program, University of Memphis, Memphis, Tennessee, USA.
Nathan P WiederholdFungus Testing Laboratory, University of Texas Health Science Center at San Antonio, San Antonio, Texas, USA.
Steven L KellyInstitute of Life Science, Swansea University Medical School, Swansea, Wales, United Kingdom.
P David RogersDepartment of Clinical Pharmacy, College of Pharmacy, University of Tennessee Health Science Center, Memphis, Tennessee, USA progers3@uthsc.edu.
University of Tennessee Health Science Center · USUniversity of Memphis · USSwansea University · GBThe University of Texas Health Science Center at San Antonio · US
Funding
Novel Azole Resistance Mechanisms in Candida albicansR01AI058145 · NIAID · UNIVERSITY OF TENNESSEE HEALTH SCI CTR · PI ROGERS, P. DAVID · 2005 to 2021
$5.8MNIAID NIH HHS R01 AI058145
Abstract
Among emerging non-
Indexed as
Antifungal AgentsAzolesCandida parapsilosisCross InfectionDrug Resistance, Multiple, FungalEchinocandinsErgosterolFungemiaGene DosageGenome, FungalHumansMicrobial Sensitivity TestsOxidoreductasesPolymorphism, Single NucleotideAntifungal AgentsAzolesEchinocandinsErgosterolOxidoreductasessterol delta-5 desaturaseantifungal resistanceantimicrobial activityantimicrobial agentsCandidaergosterolmolecular geneticsmycology
Identifiers
What OpenQuestion holds
Textmetadata
Read underepoch 390
Registered trials
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.