Evidence map›Paper›PMID 28630175›Full record

ArticleCirculation. Arrhythmia and electrophysiology2017

Patient-Specific Induced Pluripotent Stem Cell-Based Disease Model for Pathogenesis Studies and Clinical Pharmacotherapy.

Yingxin Li, Karim Sallam, Peter J Schwartz, Joseph C Wu

Open access · bronzeAbstract readEditorialComment
PubMed Full text at PMC Publisher
In one paragraph

Article in Circulation. Arrhythmia and electrophysiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.7field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 14 citations in OpenAlex.

  1. Human cardiovascular organoids: Biomedical applications and ethical challenges.American heart journal plus : cardiology research and practice · 2026
    Review
  2. Article
  3. Review
  4. Article
  5. Article
  6. Atrial Fibrillation in Inherited Channelopathies.Cardiac electrophysiology clinics · 2021
    Review
  7. Article
  8. Review
  9. Article
  10. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Yingxin LiFrom the Stanford Cardiovascular Institute, Departments of Medicine and Radiology, Institute of Stem Cell Biology & Regenerative Medicine (Y.L., K.S., J.C.W.), Stanford University, School of Medicine, CA; and Center for Cardiac Arrhythmias of Genetic Origin, IRCCS Istituto Auxologico Italiano, Milano, Italy (P.J.S.).
Karim SallamFrom the Stanford Cardiovascular Institute, Departments of Medicine and Radiology, Institute of Stem Cell Biology & Regenerative Medicine (Y.L., K.S., J.C.W.), Stanford University, School of Medicine, CA; and Center for Cardiac Arrhythmias of Genetic Origin, IRCCS Istituto Auxologico Italiano, Milano, Italy (P.J.S.).
Peter J SchwartzFrom the Stanford Cardiovascular Institute, Departments of Medicine and Radiology, Institute of Stem Cell Biology & Regenerative Medicine (Y.L., K.S., J.C.W.), Stanford University, School of Medicine, CA; and Center for Cardiac Arrhythmias of Genetic Origin, IRCCS Istituto Auxologico Italiano, Milano, Italy (P.J.S.).
Joseph C WuFrom the Stanford Cardiovascular Institute, Departments of Medicine and Radiology, Institute of Stem Cell Biology & Regenerative Medicine (Y.L., K.S., J.C.W.), Stanford University, School of Medicine, CA; and Center for Cardiac Arrhythmias of Genetic Origin, IRCCS Istituto Auxologico Italiano, Milano, Italy (P.J.S.). joewu@stanford.edu.
IRCCS Istituto Auxologico Italiano · IT

Funding

Genome Editing of Human iPSCs to Study Inherited Hypertrophic CardiomyopathyR01HL126527 · NHLBI · STANFORD UNIVERSITY · PI QI, LEI STANLEY, WU, JOSEPH C. · 2015 to 2022
$5.4M
Training in Myocardial Biology at Stanford (TIMBS)T32HL094274 · NHLBI · STANFORD UNIVERSITY · PI Euan A Ashley, Daniel Bernstein · 2010 to 2026
$5.0M
Modeling Susceptibility to Chemotherapy-Induced Cardiotoxicity Using Human iPSCsR01HL123968 · NHLBI · STANFORD UNIVERSITY · PI QUERTERMOUS, THOMAS, WU, JOSEPH C. · 2014 to 2021
$4.8M
A Systems Biology Approach to Study Cardiac Arrhythmias: iPS Cells and In Silico ModelingR01HL128170 · NHLBI · STANFORD UNIVERSITY · PI ALTMAN, RUSS BIAGIO, CLANCY, COLLEEN E · 2015 to 2018
$3.0M
Molecular Imaging of Cardiac Pluripotent Stem CellsR01HL133272 · NHLBI · STANFORD UNIVERSITY · PI WU, JOSEPH C. · 2016 to 2020
$2.4M
NHLBI NIH HHS R01 HL123968NHLBI NIH HHS R01 HL126527NHLBI NIH HHS R01 HL128170NHLBI NIH HHS R01 HL133272NHLBI NIH HHS T32 HL094274Wellcome Trust
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Diabetes Mellitus, Type 2Induced Pluripotent Stem CellsTachycardia, VentricularDrug Evaluation, PreclinicalHumansPolymorphic Catecholaminergic Ventricular TachycardiaRyanodine Receptor Calcium Release ChannelRyanodine Receptor Calcium Release Channelcardiovascular diseasesEditorialsinduced pluripotent stem cellsmyocytes, cardiacryanodine receptor calcium release channelstem cells

Identifiers

PMID28630175
PMCPMC5517015
OpenAlexW2672431130

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.