Evidence map›Paper›PMID 28630144›Full record

ArticleThe Journal of cell biology2017

CRMP-1 enhances EVL-mediated actin elongation to build lamellipodia and the actin cortex.

Hui-Chia Yu-Kemp, James P Kemp, William M Brieher

Open access · bronzeAbstract read
In one paragraph

Article in The Journal of cell biology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.1field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 26 citations in OpenAlex.

  1. Article
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  7. Cadherin puncta are interdigitated dynamic actin protrusions necessary for stable cadherin adhesion.Proceedings of the National Academy of Sciences of the United States of America · 2021
    Article
  8. Article
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  10. Actin protrusions push at apical junctions to maintain E-cadherin adhesion.Proceedings of the National Academy of Sciences of the United States of America · 2020
    Article
  11. Article
  12. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Hui-Chia Yu-KempDepartment of Cell and Developmental Biology, University of Illinois, Urbana-Champaign, IL.ORCID 0000-0002-4590-0892
James P KempDepartment of Cell and Developmental Biology, University of Illinois, Urbana-Champaign, IL.
William M BrieherDepartment of Cell and Developmental Biology, University of Illinois, Urbana-Champaign, IL wbrieher@illinois.edu.ORCID 0000-0002-3168-6688
University of Illinois Urbana-Champaign · US

Funding

Actin Assembly at Cadherin Dependent Adherens JunctionsR01GM106106 · NIGMS · UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN · PI BRIEHER, WILLIAM · 2013 to 2022
$2.6M
NIGMS NIH HHS R01 GM106106
6 · The paper itself

Abstract

Cells can control actin polymerization by nucleating new filaments or elongating existing ones. We recently identified CRMP-1 as a factor that stimulates the formation of

Indexed as

Cell MovementActin CytoskeletonActin-Related Protein 2-3 ComplexActinsAnimalsCell Adhesion MoleculesCollapsin Response Mediator Protein 1DogsEpithelial CellsMadin Darby Canine Kidney CellsMicrofilament ProteinsMicroscopy, FluorescenceMicroscopy, VideoNerve Tissue ProteinsPhosphoproteinsProtein BindingActin-Related Protein 2-3 ComplexActinsCell Adhesion MoleculesCollapsin Response Mediator Protein 1CRMP1 protein, humanEnah protein, humanEVL protein, humanMicrofilament ProteinsNerve Tissue ProteinsPhosphoproteinsVasodilator-Stimulated PhosphoproteinWasf2 protein, mouseWiskott-Aldrich Syndrome Protein Family

Identifiers

PMID28630144
PMCPMC5551698
OpenAlexW2655146467

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.