Evidence map›Paper›PMID 28630072›Full record

ArticleInfection and immunity2017

Pseudomonas Quinolone Signal Induces Oxidative Stress and Inhibits Heme Oxygenase-1 Expression in Lung Epithelial Cells.

Maher Y Abdalla, Traci Hoke, Javier Seravalli, Barbara L Switzer, Melissa Bavitz, Jill D Fliege, Peter J Murphy, Bradley E Britigan

Open access · bronzeAbstract read
In one paragraph

Article in Infection and immunity, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 45 citations in OpenAlex.

  1. Review
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  6. Kaempferol MitigatesPharmaceuticals (Basel, Switzerland) · 2025
    Article
  7. Review
  8. The role of cyano-phycocyanin as a quorum sensing inhibitor to attenuateFrontiers in cellular and infection microbiology · 2025
    Article
  9. Review
  10. Juglone as a Natural Quorum Sensing Inhibitor againstACS pharmacology & translational science · 2024
    Article
  11. PQS and pyochelin inMicrobiology spectrum · 2024
    Article
  12. Article
  13. Article
  14. Article
  15. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Maher Y AbdallaDepartment of Internal Medicine, University of Nebraska Medical Center, Omaha, Nebraska, USA maher.abdalla@unmc.edu.
Traci HokeDepartment of Internal Medicine, University of Nebraska Medical Center, Omaha, Nebraska, USA.
Javier SeravalliRedox Biology Center and Department of Biochemistry, University of Nebraska-Lincoln, Lincoln, Nebraska, USA.
Barbara L SwitzerDepartment of Internal Medicine, University of Nebraska Medical Center, Omaha, Nebraska, USA.
Melissa BavitzDepartment of Internal Medicine, University of Nebraska Medical Center, Omaha, Nebraska, USA.
Jill D FliegeDepartment of Pulmonary, Critical Care, Sleep and Allergy Medicine, University of Nebraska Medical Center, Omaha, Nebraska, USA.
Peter J MurphyDepartment of Pulmonary, Critical Care, Sleep and Allergy Medicine, University of Nebraska Medical Center, Omaha, Nebraska, USA.
Bradley E BritiganDepartment of Internal Medicine, University of Nebraska Medical Center, Omaha, Nebraska, USA.
University of Nebraska Medical Center · USOmaha VA Medical Center · USUniversity of Nebraska–Lincoln · US

Funding

Redox Biology CenterP30GM103335 · NIGMS · UNIVERSITY OF NEBRASKA LINCOLN · PI BECKER, DONALD F · 2012 to 2016
$4.3M
Development of Gallium-Based Therapies for Pulmonary Mycobacterial InfectionsI01BX002504 · VA · OMAHA VA MEDICAL CENTER · PI BRITIGAN, BRADLEY E · 2015 to 2018
–
Iron Acquisition by Mycobacterium tuberculosis Within PhagocytesI01CX000102 · VA · OMAHA VA MEDICAL CENTER · PI BRITIGAN, BRADLEY E · 2009 to 2013
–
BLRD VA I01 BX002504CSRD VA I01 CX000102NIGMS NIH HHS P30 GM103335
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Oxidative StressAnimalsCell LineEnzyme InhibitorsEpithelial CellsFlow CytometryHeme Oxygenase-1HumansMacrophagesMiceMicroscopy, ConfocalQuinolonesReactive Oxygen Species2-heptyl-3-hydroxy-4-quinoloneEnzyme InhibitorsHeme Oxygenase-1QuinolonesReactive Oxygen Speciescystic fibrosisheme oxygenase-1oxidative stressPQSPseudomonas quinolone signal

Identifiers

PMID28630072
PMCPMC5563587
OpenAlexW2657492197

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.