Evidence map›Paper›PMID 28630071›Full record

ArticleInfection and immunity2017

Albumin Inhibits Pseudomonas aeruginosa Quorum Sensing and Alters Polymicrobial Interactions.

Allie Clinton Smith, Anne Rice, Bryan Sutton, Rebecca Gabrilska, Aimee K Wessel, Marvin Whiteley, Kendra P Rumbaugh

Open access · bronzeAbstract read
In one paragraph

Article in Infection and immunity, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 54 papers.

0numbers the graph read from it
0cells of the map it votes in
54citing papers in PubMed
3.0field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

54 citing papers in PubMed, 79 citations in OpenAlex.

  1. Article
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  5. Virulence · 2025
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  7. Journal of bacteriology · 2025
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  8. Calprotectin protectsmSystems · 2025
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  10. Frontiers in medicine · 2025
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  11. Host-mimicking conditions promoteFrontiers in microbiology · 2025
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  12. Article
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  14. Review
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  16. A bacterial pigment provides cross-species protection from HProceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  17. Co-culturing withFrontiers in cellular and infection microbiology · 2024
    Article
  18. Antibiotics (Basel, Switzerland) · 2023
    Review
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 2 countries.

Allie Clinton SmithDepartment of Honors Studies, Texas Tech University, Lubbock, Texas, USA.
Anne RiceDepartment of Cell Physiology and Molecular Biophysics, Texas Tech University Health Sciences Center, Lubbock, Texas, USA.
Bryan SuttonDepartment of Cell Physiology and Molecular Biophysics, Texas Tech University Health Sciences Center, Lubbock, Texas, USA.
Rebecca GabrilskaDepartment of Surgery, Texas Tech University Health Sciences Center, Lubbock, Texas, USA.
Aimee K WesselInstitut Pasteur, Unité de Génétique des Biofilms, Paris, France.
Marvin WhiteleyDepartment of Molecular Biosciences, Institute of Cellular and Molecular Biology, Center for Infectious Disease, The University of Texas at Austin, Austin, Texas, USA.
Kendra P RumbaughDepartment of Surgery, Texas Tech University Health Sciences Center, Lubbock, Texas, USA kendra.rumbaugh@ttuhsc.edu.
Texas Tech University · USTexas Tech University Health Sciences Center · USInstitut Pasteur · FRThe University of Texas at Austin · US

Funding

Mechanisms of Pseudomonas aeruginosa virulence in polymicrobial wound infectionsR01GM116547 · NIGMS · UNIVERSITY OF TEXAS AT AUSTIN · PI WHITELEY, MARVIN · 2016 to 2019
$1.2M
Pseudomonas aeruginosa and Staphylococcus aureus Interspecies Interactions in WouR15AI105763 · NIAID · TEXAS TECH UNIVERSITY HEALTH SCIS CENTER · PI RUMBAUGH, KENDRA P · 2014 to 2014
$448k
NIAID NIH HHS R15 AI105763NIGMS NIH HHS R01 GM116547
6 · The paper itself

Abstract

Polymicrobial interactions are complex and can influence the course of an infection, as is the case when two or more species exhibit a synergism that produces a disease state not seen with any of the individual species alone. Cell-to-cell signaling is key to many of these interactions, but little is understood about how the host environment influences polymicrobial interactions or signaling between bacteria. Chronic wounds are typically polymicrobial, with

Indexed as

4-ButyrolactoneAntibiosisHumansProtein BindingPseudomonas aeruginosaQuorum SensingSerum AlbuminStaphylococcus aureus4-Butyrolactonehomoserine lactoneSerum Albuminalbuminpolymicrobial infectionPseudomonas aeruginosaquorum sensingStaphylococcus aureuswound

Identifiers

PMID28630071
PMCPMC5563583
OpenAlexW2714474752

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.