Evidence map›Paper›PMID 28629953›Full record

ArticleMagnetic resonance imaging2017

3D black blood MR angiography of the carotid arteries. A simple sequence for plaque hemorrhage and stenosis evaluation.

Monica Sigovan, Clément Bidet, Sébastien Bros, Loic Boussel, Laura Mechtouff, Philip M Robson, Zahi A Fayad, Antoine Millon, Philippe Douek

Open access · greenAbstract read
In one paragraph

Article in Magnetic resonance imaging, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
1.0field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 12 citations in OpenAlex.

  1. Pooled it
  2. Can Three-Dimensional T1-weighted MR Imaging Visualize the Vascular Lumen after Carotid Artery Stenting?Magnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine · 2025
    Article
  3. Article
  4. Article
  5. Review
  6. Review
  7. Article
  8. Frontiers in neurology · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 2 countries.

Monica SigovanCNRS UMR5220; CREATIS Laboratory, University of Lyon, Inserm U1044, INSA-Lyon, Université Lyon 1; Hospices Civils de Lyon, France. Electronic address: monica.sigovan@creatis.insa-lyon.fr.
Clément BidetUniversity of Lyon, Department of Radiology, Hospices Civils de Lyon, France.
Sébastien BrosUniversity of Lyon, Department of Radiology, Hospices Civils de Lyon, France.
Loic BousselCNRS UMR5220; CREATIS Laboratory, University of Lyon, Inserm U1044, INSA-Lyon, Université Lyon 1; Hospices Civils de Lyon, France; University of Lyon, Department of Radiology, Hospices Civils de Lyon, France.
Laura MechtouffUniversity of Lyon, Department of Vascular Neurology, Hospices Civils de Lyon, France.
Philip M RobsonTranslational and Molecular Imaging Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Zahi A FayadTranslational and Molecular Imaging Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Antoine MillonUniversity of Lyon, Department of Vascular Surgery, Hospices Civils de Lyon, France.
Philippe DouekCNRS UMR5220; CREATIS Laboratory, University of Lyon, Inserm U1044, INSA-Lyon, Université Lyon 1; Hospices Civils de Lyon, France; University of Lyon, Department of Radiology, Hospices Civils de Lyon, France.
Université Claude Bernard Lyon 1 · FRImaging Center · US

Funding

MR/PET Imaging of coronary atherosclerosisR01HL071021 · NHLBI · MOUNT SINAI SCHOOL OF MEDICINE OF NYU · PI FAYAD, ZAHI A. · 2002 to 2019
$7.8M
NHLBI NIH HHS R01 HL071021
6 · The paper itself

Abstract

objectivesTo evaluate the diagnostic performance of a new three-dimensional T1-weighted turbo-spin-echo sequence (3D T1-w TSE) compared to 3D contrast-enhanced angiography (CE-MRA) for stenosis measurement and compared to 2D T1-w TSE for intra-plaque hemorrhage (IPH) detection.

methodsEighty three patients underwent carotid MRI, using a new elliptic-centric phase encoding T1-weighted 3D TSE sequence in addition to the clinical protocol. Two observers evaluated image quality, presence of flow artifacts, and presence of intra-plaque hemorrhage, and computed the NASCET degree of stenosis for CE-MRA and for the new sequence. Inter-observer agreement and correlation between 3D TSE and CE-MRA for NASCET stenosis was estimated using Cohen's kappa, and correlation using linear regression and Bland-Altman plots. Histology was performed on endarterectomy samples for 18 patients. Sensitivity and specificity of 2D and 3D TSE for IPH diagnosis were computed.

results3D TSE showed better image quality than 2D TSE (p<0.05). Interobserver agreement was good (kappa≥0.86). Correlation between 3D TSE and CE-MRA was excellent (R=0.95) for NASCET stenosis. Sensitivity and specificity for IPH diagnosis was 50% and 100% for 2D TSE and 100% and 83% for the 3D TSE.

conclusionsThe new 3D T1-w TSE allows both reliable measures of carotid stenosis, with a slight overestimation compared to CE-MRA (5%), and improved IPH identification, compared to 2D TSE.

Indexed as

Magnetic Resonance AngiographyMagnetic Resonance ImagingAdultAgedArtifactsCarotid ArteriesCarotid StenosisColorConstriction, PathologicContrast MediaFemaleHemorrhageHumansImage Processing, Computer-AssistedImaging, Three-DimensionalMaleContrast Media3D MRIAtherosclerosisCarotid stenosisIntraplaque hemorrhage

Identifiers

PMID28629953
PMCPMC5581718
OpenAlexW2713524265

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.