ArticleEBioMedicine2017
Use of Underarm Cosmetic Products in Relation to Risk of Breast Cancer: A Case-Control Study.
Article in EBioMedicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed, 62 citations in OpenAlex.
- Therapeutic role of deferasirox loaded niosomes against aluminium-maltolate induced Alzheimer disease: A study in Swiss albino mice.The Indian journal of medical research · 2026Article
- Knowledge, attitudes, and practices regarding personal care products and their perceived link to breast cancer: a cross-sectional study.BMC women's health · 2025Article
- Association of diabetes mellitus and breast cancer in adult men and women: a cross-sectional survey.BMC cancer · 2025Article
- Review
- Exploring the Potential Link between Aluminum-Containing Deodorants/Antiperspirants and Breast Cancer: A Comprehensive Review.Current medicinal chemistry · 2025Review
- The Potential Metalloestrogenic Effect of Aluminum on Breast Cancer Risk for Antiperspirant Users.International journal of molecular sciences · 2024Review
- Use of personal care product mixtures and incident hormone-sensitive cancers in the Sister Study: A U.S.-wide prospective cohort.Environment international · 2024Article
- Biomineralogical signatures of breast microcalcifications.Science advances · 2023Article
- The postulated innocuity of lifetime exposure to aluminium should be reappraised.Frontiers in oncology · 2023Article
- Article
- Risk of breast cancer and prediagnostic urinary excretion of bisphenol A, triclosan and parabens: The Multiethnic Cohort Study.International journal of cancer · 2021Article
- Aluminum Enters Mammalian Cells and Destabilizes Chromosome Structure and Number.International journal of molecular sciences · 2021Article
- Genomic Instability Is an Early Event in Aluminium-Induced Tumorigenesis.International journal of molecular sciences · 2020Article
- Use of skincare products and risk of cancer of the breast and endometrium: a prospective cohort study.Environmental health : a global access science source · 2019Article
- Aluminium toxicosis: a review of toxic actions and effects.Interdisciplinary toxicology · 2019Review
- Urinary concentrations of environmental phenols and their associations with breast cancer incidence and mortality following breast cancer.Environment international · 2019Article
- A Case-control Study Adds a New Piece to the Aluminium/Breast Cancer Puzzle.EBioMedicine · 2017Article
Corrections and comments
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Authors and funding
10 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPrevious studies on breast cancer (BC), underarm cosmetic products (UCP) and aluminum salts have shown conflicting results. We conducted a 1:1 age-matched case-control study to investigate the risk for BC in relation to self-reported UCP application.
methodsSelf-reported history of UCP use was compared between 209 female BC patients (cases) and 209 healthy controls. Aluminum concentration in breast tissue was measured in 100 cases and 52 controls. Multivariable conditional logistic regression analysis was performed to estimate odds ratios (ORs) with 95% confidence intervals (CIs), adjusting for established BC risk factors.
findingsUse of UCP was significantly associated with risk of BC (p=0.036). The risk for BC increased by an OR of 3.88 (95% CI 1.03-14.66) in women who reported using UCP's several times daily starting at an age earlier than 30years. Aluminum in breast tissue was found in both cases and controls and was significantly associated to self-reported UCP use (p=0.009). Median (interquartile) aluminum concentrations were significantly higher (p=0.001) in cases than in controls (5.8, 2.3-12.9 versus 3.8, 2.5-5.8nmol/g).
interpretationFrequent use of UCPs may lead to an accumulation of aluminum in breast tissue. More than daily use of UCPs at younger ages may increase the risk of BC.
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