Evidence map›Paper›PMID 28629732›Full record

ArticleJournal of immunological methods2017

Impact of granulocyte contamination on PBMC integrity of shipped blood samples: Implications for multi-center studies monitoring regulatory T cells.

Charuta Agashe, David Chiang, Alexander Grishin, Madhan Masilamani, Stacie M Jones, Robert A Wood, Scott H Sicherer, A Wesley Burks, Donald Y M Leung, Peter Dawson and 2 more

Abstract read
In one paragraph

Article in Journal of immunological methods, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.3field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
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  9. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 6 institutions in 1 country.

Charuta AgashePediatric Allergy and Immunology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
David ChiangGraduate School of Biological Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Alexander GrishinPediatric Allergy and Immunology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Madhan MasilamaniPediatric Allergy and Immunology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Stacie M JonesDepartment of Pediatrics, University of Arkansas for Medical Sciences and Arkansas Children's Hospital, Little Rock, AR, USA.
Robert A WoodDepartment of Pediatrics, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Scott H SichererPediatric Allergy and Immunology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
A Wesley BurksDepartment of Pediatrics, University of North Carolina, Chapel Hill, NC, USA.
Donald Y M LeungDepartment of Pediatrics, National Jewish Health, Denver, CO, USA.
Peter DawsonThe EMMES Corporation, Rockville, MD 20850, USA.
Hugh A SampsonPediatric Allergy and Immunology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
M Cecilia BerinPediatric Allergy and Immunology, Icahn School of Medicine at Mount Sinai, New York, NY, USA. Electronic address: cecilia.berin@mssm.edu.
Icahn School of Medicine at Mount Sinai · USArkansas Children's Hospital · USEmmes (United States) · USJohns Hopkins University · USNational Jewish Health · USUniversity of North Carolina at Chapel Hill · US

Funding

Mechanistic CoreU19AI066738 · NIAID · MOUNT SINAI SCHOOL OF MEDICINE OF NYU · PI SAMPSON, HUGH A · 2005 to 2016
$43.6M
Food Allergy Research Consortium and Statistical CenterU01AI066560 · NIAID · THE EMMES COMPANY, LLC · PI DAWSON, PETER RUSSELL, LINDBLAD, ROBERT · 2005 to 2016
$12.8M
Novel tools to maximize profiling of tissue and antigen specific immune dysregulation in allergy and inflammatory bowel disesaseU24AI118644 · NIAID · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI BERIN, CECILIA, MERAD, MIRIAM · 2015 to 2020
$2.4M
Arkansas Center for Food Allergy Research (ArCOFAR)UM1AI130781 · NIAID · ARKANSAS CHILDREN'S HOSPITAL RES INST · PI JONES, STACIE M · 2017 to 2023
$1.6M
Arkansas Center for Food Allergy Research (ArCOFAR)U01AI181962 · NIAID · ARKANSAS CHILDREN'S HOSPITAL RES INST · PI Stacie M Jones · 2024 to 2026
$1.6M
NIAID NIH HHS U01 AI066560NIAID NIH HHS U01 AI181962NIAID NIH HHS U19 AI066738NIAID NIH HHS U24 AI118644NIAID NIH HHS UM1 AI130781
6 · The paper itself

Abstract

In centralized immune monitoring for a multi-center allergen immunotherapy trial, we observed frequent loss of CD4

Indexed as

Blood CellsCD4-Positive T-LymphocytesCell SurvivalFlow CytometryForkhead Transcription FactorsGranulocytesHumansLeukocytes, MononuclearMulticenter Studies as TopicSpecimen HandlingStaining and LabelingT-Lymphocytes, RegulatoryForkhead Transcription FactorsFOXP3 protein, human

Identifiers

PMID28629732
PMCPMC5573627
OpenAlexW2626464084

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.