Evidence map›Paper›PMID 28629608›Full record

ArticleAmerican journal of surgery2018

Laparotomy and intraoperative enteroscopy for obscure gastrointestinal bleeding before and after the era of video capsule endoscopy and deep enteroscopy: A tertiary center experience.

Wuttiporn Manatsathit, Usah Khrucharoen, Dennis M Jensen, O Joe Hines, Thomas Kovacs, Gordon Ohning, Rome Jutabha, Kevin Ghassemi, Gareth S Dulai, Gustavo Machicado

Abstract read
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Article in American journal of surgery, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

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2citing papers in PubMed
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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

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2 citing papers in PubMed.

  1. Observational
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors.

Wuttiporn ManatsathitDepartment of Gastroenterology and Hepatology, University of Nebraska Medical Center, Omaha, NE, United States; CURE Digestive Diseases Research Center (DDRC) - GI Hemostasis Unit, Los Angeles, CA, United States.
Usah KhrucharoenCURE Digestive Diseases Research Center (DDRC) - GI Hemostasis Unit, Los Angeles, CA, United States; David Geffen School of Medicine at UCLA, Los Angeles, CA, United States; VA Greater Los Angeles Healthcare System, Los Angeles, CA, United States.
Dennis M JensenCURE Digestive Diseases Research Center (DDRC) - GI Hemostasis Unit, Los Angeles, CA, United States; David Geffen School of Medicine at UCLA, Los Angeles, CA, United States; VA Greater Los Angeles Healthcare System, Los Angeles, CA, United States. Electronic address: djensen@mednet.ucla.edu.
O Joe HinesCURE Digestive Diseases Research Center (DDRC) - GI Hemostasis Unit, Los Angeles, CA, United States; David Geffen School of Medicine at UCLA, Los Angeles, CA, United States; Department of Surgery, Ronald Reagan UCLA Medical Center, Los Angeles, CA, United States.
Thomas KovacsCURE Digestive Diseases Research Center (DDRC) - GI Hemostasis Unit, Los Angeles, CA, United States; David Geffen School of Medicine at UCLA, Los Angeles, CA, United States; VA Greater Los Angeles Healthcare System, Los Angeles, CA, United States.
Gordon OhningCURE Digestive Diseases Research Center (DDRC) - GI Hemostasis Unit, Los Angeles, CA, United States; David Geffen School of Medicine at UCLA, Los Angeles, CA, United States; VA Greater Los Angeles Healthcare System, Los Angeles, CA, United States.
Rome JutabhaCURE Digestive Diseases Research Center (DDRC) - GI Hemostasis Unit, Los Angeles, CA, United States; David Geffen School of Medicine at UCLA, Los Angeles, CA, United States.
Kevin GhassemiCURE Digestive Diseases Research Center (DDRC) - GI Hemostasis Unit, Los Angeles, CA, United States; David Geffen School of Medicine at UCLA, Los Angeles, CA, United States.
Gareth S DulaiCURE Digestive Diseases Research Center (DDRC) - GI Hemostasis Unit, Los Angeles, CA, United States; David Geffen School of Medicine at UCLA, Los Angeles, CA, United States; VA Greater Los Angeles Healthcare System, Los Angeles, CA, United States.
Gustavo MachicadoCURE Digestive Diseases Research Center (DDRC) - GI Hemostasis Unit, Los Angeles, CA, United States; David Geffen School of Medicine at UCLA, Los Angeles, CA, United States; VA Greater Los Angeles Healthcare System, Los Angeles, CA, United States.

Funding

Pilot and Feasibility ProgramP30DK041301 · NIDDK · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI ROZENGURT, JUAN ENRIQUE · 1990 to 2019
$18.0M
CSRD VA CLIN-013-07FNIDDK NIH HHS P30 DK041301
6 · The paper itself

Abstract

backgroundTo evaluate roles of intraoperative endoscopy (IOE) in management of severe obscure GI bleeding (OGIB) before vs. after introduction of video capsule endoscopy (VCE) and deep enteroscopy (DE).

methodsWe retrospectively reviewed prospectively collected data of patients undergoing IOE for severe OGIB in a tertiary referral center.

results52 patients had laparotomy/IOE for OGIB, 11 pre and 41 post VCE/DE eras. In the pre VCE/DE era, 36.4% (4/11) had preoperative presumptive diagnoses while in the post VCE/DE era presumptive diagnoses were made in 48.8% (20/41) (p = 0.18). Preoperative evaluation led to correct diagnoses in 18.2% (2/11) in the pre and 51.2% (21/41) in the post VCE/DE era (p = 0.09). Vascular lesions and ulcers were the most common diagnoses, but rebleeding was common. No rebleeding was found among patients with tumors, Meckel's diverticulum, and aortoenteric fistula.

conclusionsPresumptive diagnoses in the post VCE/DE era were usually accurate. If VCE or DE are negative, the probability of negative IOE is high. Patients with tumors and Meckel's diverticulum were the best candidates for IOE.

Indexed as

Capsule EndoscopyEndoscopy, GastrointestinalFemaleGastrointestinal HemorrhageHemostasis, EndoscopicHumansIntraoperative CareMaleMiddle AgedRetrospective StudiesRisk FactorsTreatment OutcomeDeep enteroscopyExploratory laparotomyIntraoperative enteroscopyObscure gastrointestinal bleedingVideo capsule endoscopy

Identifiers

PMID28629608
PMCPMC5732903

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.