Evidence map›Paper›PMID 28629461›Full record

SynthesisBMC health services research2017

Cost-effectiveness of lung cancer screening and treatment methods: a systematic review of systematic reviews.

Farbod Ebadifard Azar, Saber Azami-Aghdash, Fatemeh Pournaghi-Azar, Alireza Mazdaki, Aziz Rezapour, Parvin Ebrahimi, Negar Yousefzadeh

Abstract readSystematic Review
In one paragraph

Synthesis in BMC health services research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
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  5. Impacts of accreditation on the performance of primary health care centres: A systematic review.Malaysian family physician : the official journal of the Academy of Family Physicians of Malaysia · 2023
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  18. Sensors for detecting pulmonary diseases from exhaled breath.European respiratory review : an official journal of the European Respiratory Society · 2019
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Farbod Ebadifard AzarHealth Promotion Research Center, Iran University of Medical Sciences, Tehran, Iran.
Saber Azami-AghdashRoad Traffic Injury Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
Fatemeh Pournaghi-AzarDental and Periodental Research Centre, Tabriz University of Medical Sciences, Tabriz, Iran.
Alireza MazdakiHealth Management and Economics Research Center, Iran University of Medical Sciences, Tehran, Iran.
Aziz RezapourHealth Management and Economics Research Center, Iran University of Medical Sciences, Tehran, Iran. rezapoor_a57@yahoo.com.
Parvin EbrahimiDepartment of Health service Management, School of Health Management and Information Sciences & Health Management and Economics Research Center, Iran University of Medical Sciences, Tehran, Iran.
Negar YousefzadehHealth Management and Economics Research Center, Iran University of Medical Sciences, Tehran, Iran.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDue to extensive literature in the field of lung cancer and their heterogeneous results, the aim of this study was to systematically review of systematic reviews studies which reviewed the cost-effectiveness of various lung cancer screening and treatment methods.

methodsIn this systematic review of systematic reviews study, required data were collected searching the following key words which selected from Mesh: "lung cancer", "lung oncology", "lung Carcinoma", "lung neoplasm", "lung tumors", "cost- effectiveness", "systematic review" and "Meta-analysis". The following databases were searched: PubMed, Cochrane Library electronic databases, Google Scholar, and Scopus. Two reviewers (RA and A-AS) evaluated the articles according to the checklist of "assessment of multiple systematic reviews" (AMSTAR) tool.

resultsOverall, information of 110 papers was discussed in eight systematic reviews. Authors focused on cost-effectiveness of lung cancer treatments in five systematic reviews. Targeted therapy options (bevacizumab, Erlotinib and Crizotinib) show an acceptable cost-effectiveness. Results of three studies failed to show cost-effectiveness of screening methods. None of the studies had used the meta-analysis method. The Quality of Health Economic Studies (QHES) tool and Drummond checklist were mostly used in assessing the quality of articles. Most perspective was related to the Payer (64 times) and the lowest was related to Social (11times). Most cases referred to Incremental analysis (82%) and also the lowest point of referral was related to Discounting (in 49% of the cases). The average quality score of included studies was calculated 9.2% from 11.

conclusionsTargeted therapy can be an option for the treatment of lung cancer. Evaluation of the cost-effectiveness of computerized tomographic colonography (CTC) in lung cancer screening is recommended. The perspective of the community should be more taken into consideration in studies of cost-effectiveness. Paying more attention to the topic of Discounting will be necessary in the studies.

Indexed as

Antineoplastic AgentsEarly Detection of CancerLung NeoplasmsCost-Benefit AnalysisHumansMeta-Analysis as TopicSystematic Reviews as TopicTomography, X-Ray ComputedAntineoplastic AgentsCost-effectivenessLung cancerScreeningSystematic reviewTreatment

Identifiers

PMID28629461
PMCPMC5477275

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.