ArticleBMC complementary and alternative medicine2017
Antibacterial activity of crude extracts of some South African medicinal plants against multidrug resistant etiological agents of diarrhoea.
Article in BMC complementary and alternative medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.
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Who cites it
17 citing papers in PubMed, 1 synthesis or guideline pooled it, 63 citations in OpenAlex.
- Ethnobotany, phytochemistry, and biological activities ofFrontiers in pharmacology · 2024Pooled it
- A Review of the Properties of Clinically Evaluated Plant-Derived Agents in the Treatment of Respiratory Infections.Nutrients · 2026Review
- Unlocking the therapeutic potential ofHeliyon · 2024Article
- Mitigation Potential of Herbal Extracts and Constituent Bioactive Compounds onAnimals : an open access journal from MDPI · 2024Review
- A scoping review on efficacy and safety of medicinal plants used for the treatment of diarrhea in sub-Saharan Africa.Tropical medicine and health · 2024Article
- Chemical Profile, Antioxidant and Antibacterial Activities, Mechanisms of Action of the Leaf Extract ofPlants (Basel, Switzerland) · 2023Article
- Phytochemicals: potential alternative strategy to fightFrontiers in veterinary science · 2023Review
- Ethnobotany, Ethnopharmacology, and Phytochemistry of Medicinal Plants Used for Treating Human Diarrheal Cases in Rwanda: A Review.Antibiotics (Basel, Switzerland) · 2021Review
- Antibacterial, Antihemolytic, Cytotoxic, Anticancer, and Antileishmanial Effects ofPlants (Basel, Switzerland) · 2021Article
- An Evolving Technology That Integrates Classical Methods with Continuous Technological Developments: Thin-Layer Chromatography Bioautography.Molecules (Basel, Switzerland) · 2021Review
- Antioxidant-rich Clove Extract, A Strong Antimicrobial Agent against Urinary Tract Infections-causing BacteriaTropical life sciences research · 2021Article
- Understanding the Ethnobotany, Chemistry, Pharmacology, and Distribution of GenusPlants (Basel, Switzerland) · 2021Review
- Isolation of endophytic bacteria from the leaves of Anredera cordifolia CIX1 for metabolites and their biological activities.BMC complementary medicine and therapies · 2020Article
- A Systematic Review of Plants With Antibacterial Activities: A Taxonomic and Phylogenetic Perspective.Frontiers in pharmacology · 2020Review
- Review
- Hindering the formation and promoting the dispersion of medical biofilms: non-lethal effects of seagrass extracts.BMC complementary and alternative medicine · 2018Article
- Evaluation of Antioxidant Activity and Growth Control Properties of Nonoscale Structure Produced from Aloe vera var. littoralis Extract on Clinical Isolates of Salmonella.Scientia pharmaceutica · 2017Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThis study evaluated the antibacterial activity of some plants used in folklore medicine to treat diarrhoea in the Eastern Cape Province, South Africa.
methodsThe acetone extracts of Acacia mearnsii De Wild., Aloe arborescens Mill., A. striata Haw., Cyathula uncinulata (Schrad.) Schinz, Eucomis autumnalis (Mill.) Chitt., E. comosa (Houtt.) Wehrh., Hermbstaedtia odorata (Burch. ex Moq.) T.Cooke, Hydnora africana Thunb, Hypoxis latifolia Wight, Pelargonium sidoides DC, Psidium guajava L and Schizocarphus nervosus (Burch.) van der Merwe were screened against Staphylococcus aureus, Escherichia coli, Enterococcus faecalis, multi-resistant Salmonella enterica serovar Isangi, S. typhi, S. enterica serovar Typhimurium, Shigella flexneri type 1b and Sh. sonnei phase II. A qualitative phytochemical screening of the plants extracts was by thin layer chromatography. Plants extracts were screened for antibacterial activity using serial dilution microplate technique and bioautography.
resultsThe TLC fingerprint indicated the presence of terpenoids and flavonoids in the herbs. Most of the tested organisms were sensitive to the crude acetone extracts with minimum inhibitory concentration (MIC) values ranging from 0.018-2.5 mg/mℓ. Extracts of A. striata, C. uncinulata, E. autumnalis and P. guajava were more active against enteropathogens. S. aureus and Sh. flexneri were the most sensitive isolates to the crude extracts but of significance is the antibacterial activity of A. arborescens and P. guajava against a confirmed extended spectrum betalactamase positive S. enterica serovar Typhimurium.
conclusionThe presence of bioactive compounds and the antibacterial activity of some of the selected herbs against multidrug resistant enteric agents corroborate assertions by traditional healers on their efficacies.
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